Antral follicles develop in xenografted cryopreserved african elephant (Loxodonta africana) ovarian tissue

Gunasena, Karen T.; Lakey, Jonathan R. T.; Villines, P.M.; Bush, M.; Raath, C; Critser, E.S.; McGann, Locksley E.; Critser, John K.

doi:10.1016/s0378-4320(98)00132-8

Cited by 66 publications

(28 citation statements)

References 16 publications

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“…1). Xenogenetic transplantation of the ovarian cortex into several mouse strains carrying mutation with immunodeficiency has been employed and established to determine the potential of gonadal function and fertility of cryopreserved ovaries from mice [18], cats [19], marsupials [20], sheep [18], marmoset monkeys [21], elephants [22], and humans [23,24]. Immunodeficient mice are p r o m i s i n g r e s e a r c h m o d e l s f o r o v a r i a n xenografting.…”

Section: Discussionmentioning

confidence: 99%

Cryopreservation of Canine Ovaries by Vitrification

Ishijima

Kobayashi

Lee

et al. 2006

Journal of Reproduction and Development

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Abstract. The cryopreservation of ovarian tissues is a technology with significant potential for the preservation of the genetic resource materials of working dogs, including guide dogs for the blind. However, no attempt has been reported on cryopreservation of the canine ovary. Thus, we evaluated a vitrification method for cryopreservation of canine ovaries and determined the potential functionality of vitrified-warmed canine ovaries by means of transplantation into non-obese diabeticsevere combined immunodeficiency (NOD-SCID) mice. All ovarian tissues cryopreserved by vitrification were morphologically normal in terms of histology. Cryopreserved ovaries were transplanted into the ovarian bursa of the NOD-SCID mice, and the xenografts were recovered from 23 of 23 mice (100%) 4 weeks after the operation. The transplanted canine tissue was tightly adhered to the mouse ovary. Although antral follicle formation did not occur after grafting, proliferating cell nuclear antigen immunoreactivity was detectable in many of the granulosa cells in the primary follicles of the grafts. These results indicate that cryopreservation of the canine ovary by vitrification appears to have the potential to restore endocrine function and ovulation potential.

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Section: Discussionmentioning

confidence: 99%

Cryopreservation of Canine Ovaries by Vitrification

Ishijima

Kobayashi

Lee

et al. 2006

Journal of Reproduction and Development

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“…Moreover, gonad rescuing techniques (preantral follicle culture) have already been tested in non-domestic felids [33]. Finally, antral follicle development in xenografted cryopreserved elephant ovarian tissue [24] or spermatogonial sperm cell transplantation after thawing in mice followed by restoration of spermatogenesis [13] could be future reproductive biotechnologies for endangered species.…”

Section: Other Biotechnologies and Future Applicationsmentioning

confidence: 99%

Reproductive biotechnologies for endangered mammalian species

2000

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-Assisted reproductive techniques (gamete cryopreservation, artificial insemination, embryo transfer, and in vitro fertilization) allow to propagate small fragmented populations of wild endangered species or domestic breeds. There are the best way for producing several offspring from selected genitors in order to avoid inbreeding depression. However, few mammalian species have been well studied for their reproductive biology whereas huge differences have been observed between these species. Furthermore, materials, methods and experimental designs have to be adapted for each case and each limiting factor (wildness, poor quantity of biological material, disparate locations). Genome resource banking is currently arising and the most applied reproductive biotechnology remains artificial insemination. Assisted reproductive techniques currently developed in domestic species (intracytoplasmic sperm injection, nuclear transfer) may offer new opportunities for the propagation of endangered species. endangered species / artificial insemination / cryopreservation / in vitro fertilization / embryo Résumé -Biotechnologies de la reproduction appliquées aux mammifères en voie de disparition. Les techniques de reproduction assistée (cryoconservation des gamètes, insémination artificielle, transfert embryonnaire, fécondation in vitro) permettent d'accroître des populations, parfois dispersées géographiquement, d'espèces sauvages ou domestiques en voie de disparition. Ces méthodes sont le meilleur moyen pour produire plusieurs descendants à partir de géniteurs sélectionnés de façon à éviter la consanguinité. La biologie de la reproduction est connue pour peu d'espèces de mammifères alors que de grandes différences ont pourtant été mises en évidence entre ces espèces. En outre, les matériels, les méthodes, ainsi que les schémas expérimentaux doivent être adaptés à chaque cas et pour chaque facteur limitant (animaux sauvages, peu de matériel biologique, populations dispersées). Des banques génétiques sont actuellement en voie de constitution mais la technique la plus utilisée reste l'insémination artificielle. Cependant, des biotechnologies de la reproduction en cours de mise au point chez les animaux domestiques (injection intra-cytoplasmique de spermatozoïde, transfert nucléaire) pourraient offrir de nouvelles possibilités pour l'accroissement de populations menacées. espèces menacées / insémination artificielle / congélation / fécondation in vitro / embryon Reprod. Nutr. Dev. 40 (2000)

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“…This has been attempted once when cryopreserved African elephant ovarian tissue slices were transplanted into nude mice (Gunasena et al 1998 ). These mice supported the development of antral follicles but oocytes were generally of poor quality.…”

Section: "Canonical" Interspecifi C Somatic Cells Nuclear Transfer (Imentioning

confidence: 99%

Cloning the Mammoth: A Complicated Task or Just a Dream?

Loi

Saragusty

Ptak

2014

Advances in Experimental Medicine and Biology

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Recently there has been growing interest in applying the most advanced embryological tools, particularly cloning, to bring extinct species back to life, with a particular focus on the woolly mammoth (Mammuthus primigenius). Mammoth's bodies found in the permafrost are relatively well preserved, with identifiable nuclei in their tissues. The purpose of this chapter is to review the literature published on the topic, and to present the strategies potentially suitable for a mammoth cloning project, with a frank assessment of their feasibility and the ethical issues involved.

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Antral follicles develop in xenografted cryopreserved african elephant (Loxodonta africana) ovarian tissue

Cited by 66 publications

References 16 publications

Cryopreservation of Canine Ovaries by Vitrification

Cryopreservation of Canine Ovaries by Vitrification

Reproductive biotechnologies for endangered mammalian species

Cloning the Mammoth: A Complicated Task or Just a Dream?

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