Antiviral activity of 1-methylascorbigen in experimental arbovirus infections

Berezina, L. K.; Posevaya, T. A.; Баринский, И Ф; Королев, А. М.; Zakharov, V. E.; Preobrazhenskaya, M. N.

doi:10.1007/bf00772857

Cited by 1 publication

(1 citation statement)

References 1 publication

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Asc and some of its synthetic derivatives have a variety of biological activity. The most active derivative, MeAsc, inhibits tumour growth in animals [11 14], protects animals from some bacterial and viral infections [14,15] and also has immunostimulant activity [ 13] and a pronounced apoprotic effect [16]. The special biological activity of MeAsc, study of the metabolism of the compound, and the hope of eventually obtaining Asc, MeAsc, and other MeAsc-like substances from plant material has motivated the development of efficient 0% NH…”

Section: Introductionmentioning

confidence: 99%

Critical evaluation of experimental conditions influencing the surface-enhanced Raman spectroscopic (SERS) detection of substances separated by layer liquid chromatographic techniques

et al. 2000

View full text Add to dashboard Cite

SummarySurface-enhanced Raman spectra (SERS) of p-dimethylaminobenzylidenerhodanine have been recorded on silica gel 60 F254 and Si60 F254 Raman TLC plates. Spectra were enhanced by use of a silver sol prepared according to the modified Lee-Meisel procedure. The standard deviations of the intensities and the band ratios for the seven most intense peaks were calculated for 30 parallel measurements. Although the Raman plate gives more reproducible results, several experimental difficulties are encountered in the development of chromatograms. SERS detection ofascorbigen and 1 '-methylascorbigen was performed after chromatography on silica gel 60 F254 TLC and HPTLC plates and on Si60 F254 Raman TLC plates. Traditional development was used for the silica gel 60 F254 TLC plates and Si60 F254 Raman plates, and the personal OPLC technique for the silica gel 60 F254 HPTLC plates. It was found that the SERS spectrum gave information about the indole ring only. Because bonding of the analyte to the stationary phase results in a change in molecular conformation-in contrast with the behaviour of rhodanine-the type of the plate used and the development procedure employed can significantly influence the quality of the SERS spectrum.

show abstract

Section: Introductionmentioning

confidence: 99%