Antitumor activity of tatariside F isolated from roots of Fagopyrum tataricum (L.) Gaertn against H22 hepatocellular carcinoma via up-regulation of p53

Inhibitory effects of total saponins from Ilex pubescens Hook against hydrogen peroxide-induced cardiomyocyte apoptosis

“…In addition, oxidative stress leads to over-production of oxygen free radicals, which can induce cell apoptosis by damaging cell membrane and enzymes [2] MDA, one of the main end products of lipid peroxidation, is reported to be used as an indicator of tissue damages. CAT and SOD are the important anti-oxidative enzymes, and commonly considered as the antioxidant defense system in body which plays crucial roles in suppression of oxidative stress [17]. The present results demonstrated that LPTS could increase the CAT and SOD levels in H 2 O 2 induced H9c2 cell, whereas the MDA level decreased.…”

Inhibitory Effects of Various Ratios of Polysaccharides/Alkaloids from Rhizome of <i>Coptis chinensis</i> Franch on α-Glucosidase

“…Increasingly, investigations have indicated that natural monomers/extracts isolated from plants or herbs are a potential resource for developing novel effective candidate drugs with low toxicity [17][18][19]. Here we have presented, to the best of our knowledge, the first report on the optimum ratio of polysaccharides and alkaloids (3:1) isolated from the rhizome of Coptis chinensis for inhibiting α-glucosidase.…”

Effect of acetone extract of <i>Rumex japonicas</i> Houtt on hydrogen peroxide-induced apoptosis in rat myocardial cells

“…The results demonstrate that AER can alleviate the myocardial apoptosis induced by H 2 O 2 ; furthermore, AER can also alleviate the leakages of CK and LDH from the cytoplasm due to H 2 O 2 induced cell membrane damage. In oxidative stress, MDA is a major end-product of lipid peroxidation, and is considered as an indicator of tissue damage [23]. In contrast, GAT and SOD, the crucial anti-oxidative enzymes, are considered as antioxidant defense system in body which plays crucial roles in suppressing oxidative stress [24].…”