Antitumor activity of genetically engineered NK-cells in non-hematological solid tumor: a comprehensive review
Chinmayee Priyadarsini Dash,
Dhruba Sonowal,
Prachi Dhaka
et al.
Abstract:Recent advancements in genetic engineering have made it possible to modify Natural Killer (NK) cells to enhance their ability to fight against various cancers, including solid tumors. This comprehensive overview discusses the current status of genetically engineered chimeric antigen receptor NK-cell therapies and their potential for treating solid tumors. We explore the inherent characteristics of NK cells and their role in immune regulation and tumor surveillance. Moreover, we examine the strategies used to g… Show more
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