Antitissue Transglutaminase and Antithyroid Autoantibodies in Children with Down Syndrome and Celiac Disease
Tony Hansson,
Ingrid Dahlbom,
Siv Rogberg
et al.
Abstract:Objectives:We measured circulating autoantibodies and evaluated the potential of circulating antitissue transglutaminase (tTG) antibodies to determine the presence of celiac disease (CD) in children with Down syndrome.Methods:An ELISA based on recombinant human tTG was used to measure the levels of immunoglobulin A and immunoglobulin G antibodies in serum samples from 72 children with Down syndrome, 52 children with biopsy‐verified CD, 21 disease controls with a normal small intestinal mucosa and 23 healthy co… Show more
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