Antistress Activity of Tinospora Cordifolia with Application of Yoga

Abstract

Aim: Mental stress can lead to various biochemicals, physiological and psychological changes in human body. The present study was designed to evaluate the antistress activities of Tinospora cordifolia (wild) Miers associated with yogaMethods: A randomized double blind placebo control 8 weeks study was conducted. The mental stress patients were diagnosed clinically by using different validated psychological rating scales. A total of 63 patients with mental stress were randomized into four groups. The antistress activities of the treatments were measured by different psychological rating scales as well as various biochemical parameters i.e. lipid profile, serum glucose concentration.Results: The serum glucose, lipid like triglyceride, cholesterol, ldl –cholesterol and psychological parameters like anxiety, depression were significantly increases in patients with chronic mental stress. However following treatment with Tinospora cordifolia associated with practice of yoga significantly reduced various stress induced psychological and biochemical parameters (P< 0.001)Conclusion: The findings of the clinical study suggested that Tinospora cordifolia and practice of yoga have significant anti stress activities as shown by its mitigating effects on chronic stress induced psychological and biochemical perturbation comparable to that induced by well known adaptogenic agent diazepam.Â

Amelioration of AlCl3-induced Memory Loss in the Rats by an Aqueous Extract of Guduchi, a Medhya Rasayana

“…48 A randomized, double-blind placebo control study has shown that Tinospora cordifolia treatment in combination with yoga helps to reduce mental stress in patients. 49 A decrease in catalase, SOD, GSH, and an increase in MDA/LPO level, as well as neuronal damage in the cortex and hippocampus regions of the brain, were all signs indicating a considerable increase in oxidative stress in the brain following aluminium chloride therapy in the current study. According to earlier research, aluminium stimulates and activates LPO when there is iron present in the brain.…”

“…48 A randomized, double-blind placebo control study has shown that Tinospora cordifolia treatment in combination with yoga helps to reduce mental stress in patients. 49…”