Antispasmodic activity of essential oil from Lippia dulcis Trev.

Chemical composition and pharmacological properties of the essential oils obtained seasonally fromLippia thymoides

“…Furthermore, the sesquiterpene b-caryophyllene present in L. thymoides also appears as the main compound in other species at 11% in Lippia americana2 (Bueno et al, 2011), 15-16% in L. graveolens (Rivero-Cruz et al, 2011, 13% in Lippia multiflora Moldenke (Bassolé et al, 2010), and 18% in L. dulcis (Moreno-Murillo et al, 2010). Minor compounds present in the essential oils from L. thymoides are also in other species of the same genus, as camphor at 33% in L. dulcis (Görnemann et al, 2008), borneol at 9% in Lippia integrifolia Griseb. Hieron.…”

“…The majority of the Lippia species are found in Brazil, with about 150 species present especially in the Cerrado and rocky fields (Salimena, 2002). Economical interest have induced studies on the essential oils of these species (Lampasona & Catalan, 2002) that have shown great variation in the chemical composition; the components that were found in the highest frequency were limonene, b-caryophyllene, p-cymene, camphor, linalool, a-pinene, and thymol (Pascual et al, 2001), as well as biological activities such antihelmintic (Camurça-Vasconcelos et al, 2007, antimicrobial (Albuquerque et al, 2006;Botelho et al, 2007;Pessoa et al, 2005), antioxidant (Arana-Sánchez et al, 2010;RochaGuzmán et al, 2007), antispasmodic (Görnemann et al, 2008), vasorelaxant (Maynard et al, 2011), analgesic, antiinflammatory (Abena et al, 2003;Mendes et al, 2010), and larvicidal against Aedes aegypti (Cavalcanti et al, 2004;Carvalho et al, 2003). Despite the potential demonstrated by this genus, studies are concentrated in few species, for instance Lippia sidoides Cham., Lippia alba (Mill.)…”

Supercritical Fluid Extraction of Bioactive Compounds: Fundamentals, Applications and Economic Perspectives

“…D 1 , D 2 , D 3 depressurization step (10 min). C continuous extraction step (120 min) (Zaidul et al 2007) (Pereira et al 2004) as antiviral, antibacterial, anti-inflammatory, antioxidant, anti-spasmodic, and others (Chao et al 2005;Gornemann et al 2008;Kim et al 1995;Jirovetz et al 2006;MimicaDukic et al 2004;Sivropoulou et al 1997;Tuberoso et al 2005). Due to these properties, essential oils have been used as ingredients of cosmetics, food, and pharmaceutical products.…”

Antioxidant activity of supercritical carbon dioxide extracts of Salvia desoleana on two human endothelial cell models

“…Several pharmacological properties have been attributed to essential oils (Chao et al, 2005;Gornemann, Nayal, Pertz, & Melzig, 2008;Jirovetz et al, 2006;Kim, Marshall, & Wei, 1995;Mimica-Dukic, Bozin, Sokovic, & Simin, 2004;Sivropoulou et al, 1997;Tuberoso et al, 2005) and it is therefore important not to confuse the pharmacological activity of plant-derived volatiles with pharmacological activity of the isolated compounds. For instance, the volatile oil of rosmarinus is antibacterial, while the infusion of the plant is used for the treatment of digestive diseases (Simões, Schenkel, Gosmann, Auler Mentz, & Petrovick, 1999).…”