Antipsychotic treatment dosing profile in patients with schizophrenia evaluated with electronic monitoring (MEMS®)

Artiles, Francisco Javier Acosta; Ramallo-Fariña, Yolanda; Bosch, Esperanza; Mayans, Teresa; Rodríguez, Carlos Javier Rincón; Caravaca, Ana

doi:10.1016/j.schres.2013.02.016

Cited by 18 publications

(12 citation statements)

References 26 publications

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“…Relapse in patients with schizophrenia is closely related to medication adherence, 1 2 3 which itself has many influences. 4 5 To date, numerous reports have considered different ways of checking medication adherence, including patient questioning, relative questioning, medication adherence rating, electronic monitoring using MEMS (Medication Event Monitoring System), 6 7 8 pill counting, and injection counting. 9 10 …”

Section: Introductionmentioning

confidence: 99%

Association between Medication Adherence and Duration of Outpatient Treatment in Patients with Schizophrenia

Tarutani

Kikuyama

Ohta

et al. 2016

Psychiatry Investig

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ObjectiveMedication adherence is important in the treatment of schizophrenia, and critical periods during treatment may be associated with relapse. However, the relationship between adherence and duration of outpatient treatment (DOT) remains unclear. The authors aimed to clarify the relationship between adherence and DOT at a psychiatric hospital in Japan.MethodsFor outpatients with schizophrenia who regularly visit Shin-Abuyama hospital, the authors conducted a single questionnaire survey (five questions covering gender, age, DOT, medication shortages, and residual medication) over one month period. Participants were divided into two groups whether DOT were from more than one year to within five years or not. Mantel-Haenszel analysis and logistic regression analysis were performed on the data regarding the medication adherence.ResultsEffective answers were received for 328 patients. The residual medication rate was significantly higher among those receiving outpatient treatment from more than one year to within five years than five years than those receiving outpatient treatment for more than five years or less than one year (p=0.016).ConclusionThis survey suggests that there are critical periods during which patients are most prone to poor adherence. Because poor adherence increases the risk of relapse, specific measures must be taken to improve adherence during these periods.

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Section: Introductionmentioning

confidence: 99%

Association between Medication Adherence and Duration of Outpatient Treatment in Patients with Schizophrenia

Tarutani

Kikuyama

Ohta

et al. 2016

Psychiatry Investig

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“…Other administrative claims-based studies have reported that 43-62.5% of individuals are adherent with antipsychotic medications 19,35,36 . Methods using the more sophisticated Medication Event Monitoring System (MEMS) that electronically monitor the opening of pill bottles have also reported poor adherence with antipsychotic medication [37][38][39] . While studies using selfreport or clinicians' estimates are more common 34,40 , they tend to over-estimate adherence, and have been found to have poor agreement with objective methods such as MEMS 39 or pharmacy claims 36 .…”

Section: Discussionmentioning

confidence: 99%

Examining quality of care for individuals treated for mental health using the HEDIS mental health quality measures

Ng-Mak

Rajagopalan

2018

Current Medical Research and Opinion

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Objective: This descriptive study examined the quality of care received by individuals with serious mental illness observed in clinical care using established Healthcare Effectiveness Data and Information Set (HEDIS) measures for individuals with serious mental illness. Methods: Administrative claims (Medicaid, Medicare, and commercial) from a national health and well-being company were used to identify adults with schizophrenia or bipolar disorder. Performance rates for five HEDIS mental health quality measures were computed. Sub-group analyses examined each HEDIS measure by those who were medication adherent vs non-adherent, and by typical vs atypical antipsychotics. Results: Eighty-nine percent of the Medicaid population received a diabetes screening (vs 79% for national benchmark Medicaid rates), 81% (vs 69%) received monitoring for diabetes, 88% (vs 79%) received monitoring for cardiovascular disease, 63% (vs 60%) were adherent with antipsychotic medication, and 34% (vs 61%) had a follow-up visit with a mental health practitioner within 30 days of a discharge. The rates for individuals with Medicare coverage were similar or marginally higher than those reported for those with Medicaid coverage, while rates for the commercially insured population were lower than the other groups. Conclusions: Most (>65%) individuals with serious mental illness received the recommended screening and monitoring for diabetes and cardiovascular disease. Barriers to and reasons for lack of followup should be investigated to guide future interventions to improve follow-up after hospitalization for individuals with serious mental illness. ARTICLE HISTORY

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“…Since no studies had previously analyzed MedTracker data like those yielded from this naturalistic study, few guidelines were available to inform operationalization of study variables. We, therefore, referred to studies utilizing MEMS (Acosta et al 2013), as follows.…”

Section: Medication Adherencementioning

confidence: 99%

Medication Adherence Among Adolescents with Bipolar Disorder

Goldstein

Krantz

Merranko

et al. 2016

Journal of Child and Adolescent Psychopharmacology

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Antipsychotic treatment dosing profile in patients with schizophrenia evaluated with electronic monitoring (MEMS®)

Cited by 18 publications

References 26 publications

Association between Medication Adherence and Duration of Outpatient Treatment in Patients with Schizophrenia

Association between Medication Adherence and Duration of Outpatient Treatment in Patients with Schizophrenia

Examining quality of care for individuals treated for mental health using the HEDIS mental health quality measures

Medication Adherence Among Adolescents with Bipolar Disorder

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