Antiproliferative activity of biomass extract from Pseudomonas cedrina

Sánchez-Tafolla, Leonardo; Padrón, José M.; Mendoza, Guillermo; Luna-Rodríguez, Mauricio; Fernández, José J.; Norte, Manuel; Trigos, Ángel

doi:10.1016/j.ejbt.2019.03.010

Cited by 5 publications

(2 citation statements)

References 38 publications

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“…Pseudomonas lurida is a fluorescent species which on the one hand causes bacterial leaf spot [ 48 ] and on the other hand positively influences the growth and nutrient uptake parameters of seedlings [ 49 ]. Similar, P. cedrina strains has antiproliferative activity against human tumor cell lines [ 50 ] but also is recognised as bacterium-induced oxidative foliar photo-necrosis [ 51 ]. Additionally, P. gessardii was recently reported to improve plants' response to Pb-toxicity soils [ 52 ].…”

Section: Discussionmentioning

confidence: 99%

Stigmas of holoparasitic Phelipanche arenaria (Orobanchaceae) – a suitable ephemeric flower habitat for development unique microbiome

Ruraż,

Przemieniecki,

Błaszak

et al. 2023

BMC Plant Biol

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Background Microbial communities have occasionally been observed in part of the ephemeric reproductive structure of floral stigmas, but their prevalence, phylogenetic diversity and ecological roles are understudied. This report describes the first study of bacterial and fungal communities in immature and mature stigma tissue of the endangered holoparasitic plant Phelipanche arenaria. Culture-dependent methods coupled with next-generation sequencing indicated that a small surface of the flower stigma was an unexpectedly rich and diverse microhabitat for colonization of microbial. We also compared the enzymatic activity of the bacterial communities between immature and mature stigmas samples. Results Using high-throughput sequencing methods, we identified and classified 39 to over 51 OTUs per sample for bacterial OTUs represented by Pantoea agglomerans and P. ananatis, comprising 50.6%, followed by Pseudomonas, Luteibacter spp., Sphingomonas spp. with 17% of total frequency. The bacterial profile of immature stigmas of P. arenaria contained unique microorganisms (21 of the most numerous OTUs) that were not confirmed in mature stigmas. However, the enzymatic activity of bacteria in mature stigmas of P. arenaria showed more activity than observed in immature stigmas. In the fungal profile, we recorded even 80 OTUs in mature stigmas, consisting of Capnodiales 45.03% of the total abundance with 28.27% of frequency was created by Alternaria eichhorniae (10.55%), Mycosphaerella tassiana (9.69%), and Aureobasidium pullulans (8.03%). Additionally, numerous putative plant growth-promoting bacteria, fungal pathogens and pathogen-antagonistic yeasts were also detected. Conclusions Our study uncovered that P. arenaria stigmas host diverse bacterial and fungal communities. These microorganisms are well known and have been described as beneficial for biotechnological and environmental applications (e.g., production of different enzymes and antimicrobial compounds). This research provided valuable insight into the parasitic plant–microbe interactions.

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Section: Discussionmentioning

confidence: 99%

Stigmas of holoparasitic Phelipanche arenaria (Orobanchaceae) – a suitable ephemeric flower habitat for development unique microbiome

Ruraż,

Przemieniecki,

Błaszak

et al. 2023

BMC Plant Biol

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“…K. michiganensis is an emerging multidrug-resistant human pathogen [76]. However, P. cedrina, a bio-pesticide against Plutella xylostella [77] and reported as antiproliferative against human cervical carcinoma cell lines Hela Lung A-549 (HBL-100) [78]. The present findings corroborate the bacterial characterization in betel quid chewer and non-chewer by Deepak et al [34], poor oral hygiene and chronic periodontitis in betel nut chewers [79], microbial association with dysbiosis and increased risk of oral cancer [35].…”

Section: Plos Onementioning

confidence: 99%

Bacteria in the oral cavity of individuals consuming intoxicating substances

et al. 2023

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Food habits and oral hygiene are critical attributes for physiochemical environment of the oral cavity. Consumption of intoxicating substances such as betel nut (’Tamul’), alcohol, smoking and chewing tobacco may strongly influence the oral ecosystem including commensal microbes. Therefore, a comparative assessment of microbes in the oral cavity between individuals consuming intoxicating substances and non-consumers may indicate the influence of these substances. Oral swabs were collected from consumers of intoxicating substances and non- consumers of Assam, India, microbes were isolated by culturing on Nutrient agar and identified by phylogenetic analysis of their 16S rRNA gene sequences. The risks of consumption of intoxicating substance on occurrence of microbes and health conditions were estimated using binary logistic regression. Mostly pathogens and opportunistic pathogens were found in the oral cavity of consumers and oral cancer patients which included Pseudomonas aeruginosa, Serratia marcescens, Rhodococcus antrifimi, Paenibacillus dendritiformis, Bacillus cereus, Staphylococcus carnosus, Klebsiella michiganensis and Pseudomonas cedrina. Enterobacter hormaechei was found in the oral cavity of cancer patients but not in other cases. Pseudomonas sp. were found to be widely distributed. The risk of occurrence of these organisms were found in between 0.01 and 2.963 odds and health conditions between 0.088 and 10.148 odds on exposure to different intoxicating substances. When exposed to microbes, the risk of varying health conditions ranged between 0.108 and 2.306 odds. Chewing tobacco showed a higher risk for oral cancer (10.148 odds). Prolonged exposure to intoxicating substances conduce a favorable environment for the pathogens and opportunistic pathogens to colonize in the oral cavity of individuals consuming intoxicating substances.

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Application of Alternative Technologies for the Recovery of Bioactive Compounds from Microbial Sources

Ochoa,

Osorio-Tobón

2023

Microbial Bioactive Compounds

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Antiproliferative activity of biomass extract from Pseudomonas cedrina

Cited by 5 publications

References 38 publications

Stigmas of holoparasitic Phelipanche arenaria (Orobanchaceae) – a suitable ephemeric flower habitat for development unique microbiome

Stigmas of holoparasitic Phelipanche arenaria (Orobanchaceae) – a suitable ephemeric flower habitat for development unique microbiome

Bacteria in the oral cavity of individuals consuming intoxicating substances

Application of Alternative Technologies for the Recovery of Bioactive Compounds from Microbial Sources

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