Antiplatelet therapy in acute coronary syndrome

Abstract

Unstable angina and myocardial infarction, without or with ST elevation, are entities of acute coronary syndrome (ACS). Main pathophysiologic mechanism of ACS is rupture of atherosclerotic plaque leading to thrombus formation in coronary arteries. Different groups of medications are given for treatment of this life-threatening condition. Acetylsalicylic acid is base of therapy and choice of other medications depends on risk factors for thrombosis and bleeding, comorbidities and the ability to transfer patient to the center where coronary stent can be implanted.