2018
DOI: 10.1111/joic.12529
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Antiplatelet and anticoagulation therapy during percutaneous coronary interventions: A review for the interventionalist

Abstract: Pharmacotherapy for percutaneous coronary interventions is essential to optimize the balance between thrombosis and bleeding. Currently, choices abound for the selection of antiplatelet and anticoagulation therapies during percutaneous intervention (PCI). This review article discusses the mechanisms, pharmacokinetics/dynamics, and clinical data behind the various pharmacotherapies including; aspirin, thienopyridines, glycoprotein IIb/IIIa inhibitors, vorapaxar, heparin, direct thrombin inhibitors, and factor X… Show more

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Cited by 2 publications
(2 citation statements)
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“…The basis of the pathogenesis of many cardiovascular deceases (CVD) is atherothrombosis representing adhesion and platelet aggregation at the site of an unstable atherosclerotic plaque with an intravascular thrombus and often causes fatal complications [1]. Platelet activation is a key point in the pathogenesis of cardiovascular complications; therefore, the most complete suppression of platelets functions is the most important task in the treatment and prevention of complications.…”
Section: Introductionmentioning
confidence: 99%
“…The basis of the pathogenesis of many cardiovascular deceases (CVD) is atherothrombosis representing adhesion and platelet aggregation at the site of an unstable atherosclerotic plaque with an intravascular thrombus and often causes fatal complications [1]. Platelet activation is a key point in the pathogenesis of cardiovascular complications; therefore, the most complete suppression of platelets functions is the most important task in the treatment and prevention of complications.…”
Section: Introductionmentioning
confidence: 99%
“…/www.nucleodoconhecimento.com.br 16 RC: 122227 Disponível em: https://www.nucleodoconhecimento.com.br/saude/intervencao-coronariana hemorrágicos, é de suma importância que seja indispensável o conhecimento a respeito dos benefícios e limitações que as medicações podem apresentar(BASMAN et al, 2018).…”
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