Antiplatelet agents for preventing thrombosis after peripheral arterial bypass surgery

Dörffler‐Melly, Janine; Büller, HR; Koopman, MM; Prins, MH

doi:10.1002/14651858.cd000535

Cited by 25 publications

(22 citation statements)

References 24 publications

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“…Venous bypass grafts have high rates (25 to 30%) of stenosis within the first year. Antiplatelet agents, particularly aspirin, are the only therapy that has been shown to improve graft patency (69,70).…”

Section: Therapymentioning

confidence: 99%

Peripheral Arterial Disease

DeLoach

Mohler

2007

Clinical Journal of the American Society of Nephrology

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Cardiovascular disease is a major source of morbidity and mortality for patients with chronic kidney disease (CKD). Peripheral arterial disease (PAD) is a strong predictor of coronary artery disease and a risk factor for mortality in the general population. This is of particular interest to nephrologists because the risk for PAD is increased in CKD. Often, PAD is overlooked as a source of morbidity and as a cardiovascular risk factor in this population. This review serves as an overview of the epidemiology, screening, diagnosis, and treatment of PAD with an emphasis on CKD.

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Section: Therapymentioning

confidence: 99%

Peripheral Arterial Disease

DeLoach

Mohler

2007

Clinical Journal of the American Society of Nephrology

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“…Consistently, the tcPO 2 values were remarkably improved in the CO 2 group, but remained unchanged in the control group. These results strongly suggest that CO 2 immersion is effective against ulcer exacerbation, presumably due to the elevation of tcPO 2 .…”

Section: Discussionmentioning

confidence: 56%

“…Accordingly, after 3 months, tcPO 2 became significantly higher in the CO 2 group than in the control group. However the mean tcPCO 2 and SBF did not change in both groups ( Table 3 ). Other parameters, AP, ABI, TP, TBI, also did not change significantly.…”

Section: Effect Of Co 2 Immersion On the Tissue Oxygen Pressurementioning

confidence: 91%

“…1) Adjunctive treatments should prevent postoperative problems such as amputation, ulcer exacerbation and graft occlusion. Although recent studies have focused on the effects of medication, 2,3) a number of alternatives including spinal cord stimulation, 4) hyperbaric therapy, 5) and an intra-muscular injection of autologous bone-marrow mononuclear cells, 6) which may be also beneficial in revascularized limbs. However, the efficacy as adjunctive treatments for revascularized limbs remains unclear.…”

Section: Introductionmentioning

confidence: 99%

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Immersing Feet in Carbon Dioxide-enriched Water Prevents Expansion and Formation of Ischemic Ulcers after Surgical Revascularization in Diabetic Patients with Critical Limb Ischemia

Hayashi

Yamada

Kumada

et al. 2008

Annals of Vascular Diseases

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Objective:We investigated the effect of immersion of feet in CO 2 -enriched water for preventing expansion and formation of ischemic ulcer in critical limb ischemia of diabetic patients after surgical revascularization. Materials and methods: Eligible patients were allocated CO 2 group (CO 2 immersion plus standard care) or control group (standard care alone) and were followed up for 3 months after surgical revascularization. The end point is defined as an expansion of a target ulcer (more than 101% of original size) or the formation of new ulcers during the follow-up period. Results: Fifty-nine patients out of originally enrolled 66 patients with type II diabetes were included in intention-to-treat population. The cumulative prevention rate for ischemic ulcer after 3 months was 97.1% in the CO 2 group, while, in the control group, it was 77.8%, i.e., significantly lower than the CO 2 group ( P = 0.012, log-rank test). The transcutaneous oxygen pressure increased significantly only in the CO 2 group, from 56 Ȁ 14 to 63 Ȁ 15 mmHg ( P < 0.01, Wilcoxon signed rank test), in 3 months. Conclusion: These results suggest that addition of CO 2 immersion to standard care of critical limb ischemia in diabetic patients improves early postoperative outcome after vascular surgery.

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“…[45] In a Cochrane review, 41% reduced risk of graft occlusion was found (12 months of follow-up) in patients treated with acetylsalicylic acid following revascularization surgery. [46,47] Although in patients with coronary disease double anti-aggregation is often used in accordance with the results obtained. However, no conclusive information is available regarding its usefulness in PAD.…”

Section: Shahid Alam Et Almentioning

confidence: 97%

Current Trends and outcomes: Endovascular Management in Arteriosclerosis Obliterans (ASO) of Lower Limb Vessels

2016

ARC Journal of Surgery

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Antiplatelet agents for preventing thrombosis after peripheral arterial bypass surgery

Cited by 25 publications

References 24 publications

Peripheral Arterial Disease

Peripheral Arterial Disease

Immersing Feet in Carbon Dioxide-enriched Water Prevents Expansion and Formation of Ischemic Ulcers after Surgical Revascularization in Diabetic Patients with Critical Limb Ischemia

Current Trends and outcomes: Endovascular Management in Arteriosclerosis Obliterans (ASO) of Lower Limb Vessels

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