Antiphospholipid Syndrome: Insights into Molecular Mechanisms and Clinical Manifestations
Alessandra Ida Celia,
Mattia Galli,
Silvia Mancuso
et al.
Abstract:Antiphospholipid syndrome (APS) is a complex systemic autoimmune disorder characterized by a hypercoagulable state, leading to severe vascular thrombosis and obstetric complications. The 2023 ACR/EULAR guidelines have revolutionized the classification and understanding of APS, introducing broader diagnostic criteria that encompass previously overlooked cardiac, renal, and hematologic manifestations. Despite these advancements, diagnosing APS remains particularly challenging in seronegative patients, where trad… Show more
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