Antiphospholipid antibodies in women at risk for preeclampsia

Branch, D. Ware; Porter, T. Flint; Rittenhouse, Linda; Caritis, Steve N.; Sibai, Bahaeddine M; Hogg, Barbara B.; Lindheimer, Marshall D.; Klebanoff, Mark A.; MacPherson, Cora; VanDorsten, J. Peter; Landon, Mark B.; Paul, Richard H.; Miodovnik, Menachem; Meis, Paul J.; Thurnau, Gary R.

doi:10.1067/mob.2001.113846

Cited by 96 publications

(39 citation statements)

References 22 publications

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“…The rates of antiphospholipid antibodies reported in these studies were between 2% and 7%, a variation which might be the result of selection bias of the population and differences in laboratory methods. The antiphospholipid antibody status in patients with systemic lupus erythomatodes, in patients with recurrent miscarriages (3 or more) [93], and in patients with a history of preeclampsia [94] does not appear to predict the development of preeclampsia. Therefore antiphospholipid antibodies should be tested only when antiphospholipid syndrome is suspected.…”

Section: Systemic Lupus Erythomatosis and Antiphospholipid Syndromementioning

confidence: 92%

Clinical risk factors for preeclampsia

Gaugler-Senden

Roes

Groot

et al. 2005

Eur Clinics Obstet Gynecol

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Preeclampsia, diagnosed by increased blood pressure and de novo proteinuria, is a pregnancy-specific disease associated with a high incidence of maternal and fetal morbidity and mortality. Identification of women at risk for this potential life threatening disease might enable the clinician to identify and counsel patients adequately. A major concern in the identification of clinical risk factors for the development of preeclampsia is confusion over the clinical classification of this syndrome which has resulted from using different definitions. For this in-depth review and meta-analysis only well defined reports were selected. Maternal constitutional and environmental factors as well as pregnancy-specific changes as risk factors for the development of preeclampsia were studied. This review describes both dependent and the following independent risk factors for the development of preeclampsia: chronic hypertension, renal disease, diabetes, nulliparity, and long pregnancy interval.

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Section: Systemic Lupus Erythomatosis and Antiphospholipid Syndromementioning

confidence: 92%

Clinical risk factors for preeclampsia

Gaugler-Senden

Roes

Groot

et al. 2005

Eur Clinics Obstet Gynecol

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“…Tampoco ha aparecido asociación entre PE tardía y antecedente de PE previa, HTAC, DM pregestacional, trombofilias y TRA con respecto a lo publicado en que se demuestra la asociación de estas condiciones preexistentes con la aparición de PE precoz y no tardía 17,19,[20][21][22]23 . La literatura demuestra asociación de trombofilias con la aparición de PE precoz o severa 24 dato que puede explicar la ausencia de asociación con nuestros casos de PE tardía.…”

Section: Discussionunclassified

Screening de primer trimestre de preeclampsia tardía en gestantes de bajo riesgo en un centro de bajo volumen obstétrico: validación externa de un modelo predictivo

Cobos

Laparte

Ruiz-Zambrana

et al. 2015

Anales Sis San Navarra

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“…Many earlier studies reported risk factors for PIH like history of PIH in previous pregnancy, family history of PIH, thrombophilic disorder, obesity, dyslipidaemia [Eskenazi et al 1991, 9 Cincotta RB et al 1998, 16 Gonzalez et al 2000, 17 Ros HS et al 2000, 18 Sibai BM et al 1997, 19 Branch DW et al 2001 20 ]. Similar results were observed in our study except incidence of family history was less in the present study, may be due to exclusion of patients with chronic hypertension and other medical disorders.…”

Section: Discussionmentioning

confidence: 99%