Antioxidative and cytotoxic activity of essential oils and extracts of Satureja montana L., Coriandrum sativum L. and Ocimum basilicum L. obtained by supercritical fluid extraction

Abstract

Antioxidative and cytotoxic activity of essential oils and extracts of Satureja montana L., Coriandrum sativum L. and Ocimum basilicum L. obtained by supercritical fluid extraction

Modification of DC polarographic antioxidant assay—Application to aromatic plants and their active principles

“…The superior AO capacity of both essentials oils and extracts of Lamiaceae species in comparison to Apiaceae observed was found to be in good agreement with literature data . Based on the results presented in Table , it can be concluded that 70% ethanol is more efficient solvent in both types of extraction.…”

“…The Lamiaceae species were reported to possess a wide range of biological activity and wide diversity of phytochemicals . Ocimum basilicum L. (basil) and Satureja montana L. (winter savory) are well known aromatic plants from Lamiaceae family with proven AO capacity . These aromatic plants are commonly used as flavouring agents in cosmetic industry and as culinary herbs in traditional cuisine.…”

“…These aromatic plants are commonly used as flavouring agents in cosmetic industry and as culinary herbs in traditional cuisine. Pimpinella anisum L. (anise) and Carum carvi L. (caraway), members of Apiaceae family, are widely used as spices but they also have significant applications in cosmetic industry, pharmacology and in food industry where extracts and essential oils of these plants found application as natural food additives …”

Coriander essential oil and linalool - interactions with antibiotics against Gram-positive and Gram-negative bacteria

“…Synergistic and also additive interactions between coriander essential oil/linalool and selected antibiotics might be attributed, to a great extent, to the membrane permeabilization activity of the former which facilitates the penetration of antibiotics and consequently their action inside bacterial cell (inhibition of cell wall biosynthesis for b-lactam antibiotics, inhibition of protein synthesis for erythromycin, clindamycin, tetracycline and gentamicin, inhibition of DNA replication for ciprofloxacin) (Kohanski et al 2010). Furthermore, it is worth mentioning that the MICs of coriander essential oil and linalool reported in the present study (5Á44 and 5Á36 lg ml À1 respectively) are significantly lower than the concentrations found to be cytotoxic against human cells: IC 50 = 751 and 1253 lg ml À1 for coriander essential oil and linalool against MRC-5 and GM07492A normal human lung fibroblasts respectively (Souza et al 2016;Elgndi et al 2017), IC 50 = 81Á5, 72Á7 and 64Á7 lg ml À1 at 24, 48 and 72 h, respectively, for linalool against human hepatoma G2 cells (Erdogan and Ozkan 2017). According to Park et al 2012, the concentrations of linalool should be kept below 0Á4 mg ml À1 when used in oral hygiene products.…”

“…; Elgndi et al . ), IC 50 = 81·5, 72·7 and 64·7 μ g ml −1 at 24, 48 and 72 h, respectively, for linalool against human hepatoma G2 cells (Erdogan and Ozkan ). According to Park et al .…”