Antioxidative and Antiinflammatory Activities of the Chloroform Extract of Ganoderma lucidum Found in South India

Joseph, Soniamol

doi:10.3797/scipharm.0808-17

Cited by 55 publications

(23 citation statements)

References 29 publications

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“…The scavenging of the NO generated from sodium nitroprusside in vitro indicates the possibility of preventing the peroxynitrite formation in the cell in vivo [34]. Reducing the nitric oxide generation in the digestive tract was reported to be effective in preventing the reactions of nitrate with amines and amides to form carcinogenic nitrosamines and nitrosamides [35,36].…”

Section: Nitric Oxide Scavenging Assaymentioning

confidence: 99%

Ethnopharmacological investigations of methanolic extract of Pouzolzia Zeylanica (L.) Benn

et al. 2016

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Section: Nitric Oxide Scavenging Assaymentioning

confidence: 99%

Ethnopharmacological investigations of methanolic extract of Pouzolzia Zeylanica (L.) Benn

et al. 2016

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“…Joseph et al, [84] showed anti-inflammatory activity of the chloroform extract of G. lucidum in carrageenan induced acute and formalin induced chronic inflammatory models in mice. The extract showed remarkable anti-inflammatory activity in both models, comparable to the standard reference drug diclofenac.…”

Section: Anti-inflammatory Propertymentioning

confidence: 98%

“…Studies on fungal biomolecules as potential natural antioxidants are scanty and G. lucidum was shown to possess marked free radical scavenging and lipid peroxidation inhibition properties [84,100]. The MeOH and chloroform extracts of G. lucidum exhibited antioxidative activities.…”

Section: Anti-oxidant Propertymentioning

confidence: 99%

Ganoderma lucidum: A Potent Pharmacological Macrofungus

Sanodiya¹,

Thakur²,

Baghel³

et al. 2009

CPB

369

250

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Ganoderma lucidum (Ling Zhi) is a basidiomycete white rot macrofungus which has been used extensively as "the mushroom of immortality" in China, Japan, Korea and other Asian countries for 2000 years. A great deal of work has been carried out on therapeutic potential of Ganoderma lucidum. The basidiocarp, mycelia and spores of Ganoderma lucidum contain approximately 400 different bioactive compounds, which mainly include triterpenoids, polysaccharides, nucleotides, sterols, steroids, fatty acids, proteins/peptides and trace elements which has been reported to have a number of pharmacological effects including immunomodulation, anti-atherosclerotic, anti-inflammatory, analgesic, chemo-preventive, antitumor, chemo and radio protective, sleep promoting, antibacterial, antiviral (including anti-HIV), hypolipidemic, anti-fibrotic, hepatoprotective, anti-diabetic, anti-androgenic, anti-angiogenic, anti-herpetic, antioxidative and radical-scavenging, anti-aging, hypoglycemic, estrogenic activity and anti-ulcer properties. Ganoderma lucidum has now become recognized as an alternative adjuvant in the treatment of leukemia, carcinoma, hepatitis and diabetes. The macrofungus is very rare in nature rather not sufficient for commercial exploitation for vital therapeutic emergencies, therefore, the cultivation on solid substrates, stationary liquid medium or by submerged cultivation has become an essential aspect to meet the driving force towards the increasing demands in the international market. Present review focuses on the pharmacological aspects, cultivation methods and bioactive metabolites playing a significant role in various therapeutic applications.

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“…Since it absolutely was antecedently mentioned the role of reductants [12], in reducing ability by donating atom to interrupt the radical chain [13]. Therefore, it absolutely was speculated that the presence of reductants (i.e.…”

Section: Contentsmentioning

confidence: 99%

Estimations of Pistia stratiotes L. by using Chromatographic Methods

Ansar¹

2014

J Bioproces Biotechniq

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The leaf methanolic extract scavenged each gas NO and DPPH radical with a dose dependent manner. However the pet ether fraction of root was found to possess highest effectuality in Fe 3+ reducing power assay. Flavonoid was found to contain highest within the pet ether fraction of root in terms of quercetin equivalent, equally highest quantity of total phenolic resin compounds (assayed as acid equivalents) were found to contain within the same fraction. The methanol fractions appeared less cytotoxic compared to pet ether extracts. The plant extracts caused a dose dependent decrease in soiled BM in each cathartic and atomic number 12 sulfate induced looseness of the bowels, wherever as leaf extracts in every solvent appeared only. Also, the plant extracts showed anthelmintic activity in oligochaete worm by causing palsy and death in an exceedingly dose dependent manner. At highest doses all fractions were nearly effective because the positive management helminthic citrate. Conclusion:Thus, besides this cytotoxic effect its traditional claim for therapeutic use can never be overlooked.

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Antioxidative and Antiinflammatory Activities of the Chloroform Extract of Ganoderma lucidum Found in South India

Cited by 55 publications

References 29 publications

Ethnopharmacological investigations of methanolic extract of Pouzolzia Zeylanica (L.) Benn

Ethnopharmacological investigations of methanolic extract of Pouzolzia Zeylanica (L.) Benn

Ganoderma lucidum: A Potent Pharmacological Macrofungus

Estimations of Pistia stratiotes L. by using Chromatographic Methods

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