Antioxidant status of South Indian patients undergoing coronary artery bypass graft surgery: A role of intra operative magnesium supplementation

Changes in serum zinc and copper concentrations in patients with cardiovascular disease following cardiac surgery

“…These results were in accordance with other studies, observing that the serum Zn levels after CABG with CPB decreased significantly (Al-Bader et al, 1998;Fraser et al, 1989;Gormus et al, 2005;Yan et al, 2013). Kurian et al (2008) also observed decreased Zn levels during the ischemic stage of CABG surgery. In the early revascularization period, the concentrations of Zn in the serum were elevated, and they were observed to be decreased once more in the late revascularization stage (Kurian & Paddikkala, 2007).…”

“…Kurian et al (2008) also observed decreased Zn levels during the ischemic stage of CABG surgery. In the early revascularization period, the concentrations of Zn in the serum were elevated, and they were observed to be decreased once more in the late revascularization stage (Kurian & Paddikkala, 2007). This depletion in serum Zn might have resulted in the depletion of essential enzymes, which protect cell membranes from damage by free radicals.…”

“…This immediate postoperative decrease of Cu in CABG patients was parallel to other studies (Antila et al, 1990 ; Fraser et al, 1989 ; Gormus et al, 2005 ; Jeremy et al, 2002 ; Yan et al, 2013 ). Kurian et al ( 2008 ) observed increased Cu levels during the ischemic stage of CABG surgery and in the early revascularization period, although afterward, Cu levels were observed to be decreased in the late revascularization stage (Kurian et al, 2008 ). Other studies on patients undergoing valve replacement surgery also reported reduced postoperative concentrations of Cu (Nuutinen et al, 1981 ; Yan et al, 2013 ).…”