2002
DOI: 10.1179/135100002125000370
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Antioxidant properties of aTinospora cordifoliapolysaccharide against iron-mediated lipid damage and γ-ray induced protein damage

Abstract: The antioxidant activity of an arabinogalactan polysaccharide (TSP) isolated from Tinospora cordifolia, an Indian medicinal plant, was studied. The polysaccharide showed good protection against iron-mediated lipid peroxidation of rat brain homogenate as revealed by the thiobarbituric acid reactive substances (TBARS) and lipid hydroperoxide (LOOH) assays. TSP also provided significant protection to protein against gamma-ray induced damage. The protective action can possibly be explained by its very high reactiv… Show more

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Cited by 83 publications
(48 citation statements)
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References 23 publications
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“…Correa ex, [18][19] Bacopa monnieri, 20 Solanum nigrum Linn., 21 Plumbago zeylanica L., [22][23][24] Coriandrum sativum Linn., 25 Leucas aspera (Willd.) Link, 26 Tinospora cordifolia (Wild) Meirs., [27][28][29][30][31][32][33][34][35][36][37][38][39][40] Terminalia chebula Retz., 41 Premna integrifolia Linn., 42 Carum carvi L., 43 Piper longum L., [44][45][46][47][48][49] Centella asiatica Linn., [50][51] Cyperus rotundus L., 52 Vitex nirgundo L., 53 Nelumbo nucifera Gaertn., [54][55] Moringa oleifera Lam., [56][57] Cedrus deodara (Roxb.) Loud., 58 Acorus calamus L., 2 Boerhavia diffusa Linn., 59 Embelia ribes Burn F., 2 Citrullus colocynthis Schrad., 60 Terminalia bellerica (Gaertn.)…”
Section: Discussionunclassified
“…Correa ex, [18][19] Bacopa monnieri, 20 Solanum nigrum Linn., 21 Plumbago zeylanica L., [22][23][24] Coriandrum sativum Linn., 25 Leucas aspera (Willd.) Link, 26 Tinospora cordifolia (Wild) Meirs., [27][28][29][30][31][32][33][34][35][36][37][38][39][40] Terminalia chebula Retz., 41 Premna integrifolia Linn., 42 Carum carvi L., 43 Piper longum L., [44][45][46][47][48][49] Centella asiatica Linn., [50][51] Cyperus rotundus L., 52 Vitex nirgundo L., 53 Nelumbo nucifera Gaertn., [54][55] Moringa oleifera Lam., [56][57] Cedrus deodara (Roxb.) Loud., 58 Acorus calamus L., 2 Boerhavia diffusa Linn., 59 Embelia ribes Burn F., 2 Citrullus colocynthis Schrad., 60 Terminalia bellerica (Gaertn.)…”
Section: Discussionunclassified
“…(RC) is considered to be traditionally useful as an external application in inflammations, ulcers and skin diseases, to relieve the symptoms of pruritis, burning and exudation from skin (Jorapurkar et al, 2003a,b). The antioxidant, anti-inflammatory and immuno-modulatory properties of TC and RC has also been well documented (Tripathi et al, 1997;Kasture et al, 2001;Bishayi et al, 2002;Subramanian et al, 2002). In light of the aforementioned antiinflammatory properties of TC and RC, it is hypothesized that these herbs may be helpful in reducing the antigen-induced conjunctivitis in rats via anti-histaminic activities since inflammatory mediators like histamine is also involved in allergy.…”
Section: Introductionmentioning
confidence: 99%
“…People have isolated a series of active ingredients from natural anti-radiation substances, such as polysaccharides (Subramanian et al, 2002;Song et al, 2003;Il´in et al, 2004;Fan et al, 2005) (Devi et al, 1998;Liu et al, 2002;Zielonka et al, 2003;, polyphenols (Hibasami et al, 2000;Lv et al, 2004), saponins (Chen et al, 1999;Kim et al, 2001;Li et al, 2001;Kuinar et al, 2003), alkaloids (Liang et al, 2002;Makarchenko and Utkina 2006 ), and peptides compounds (Zhu and Zhong 2004;Yang 2007), etc. Rosa roxburghii Tratt (Figure 1) is the fruit of jiao-si flower or unicuspid jiao-si flower from rosaceae, which was firstly recorded in the "ben-cao-gang-mu-shi-yi".…”
Section: Introductionmentioning
confidence: 99%