Antioxidant potential of Salicornia arabica lipid extract and their protective effect against cadmium induced oxidative stress in erythrocytes isolated from rats

Hammami, Nadia; Athmouni, Khaled; Lahmar, Imen Ben; Abdallah, Ferjani Ben; Belghith, Karima

doi:10.1007/s11694-019-00191-8

Cited by 6 publications

(2 citation statements)

References 33 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Salicornia arabica ( S. arabica ) lipid extract was reported to induce a protective effect against cadmium-induced erythrocyte damage. In vitro, the antioxidant properties of S. arabica polysaccharides and lipid extracts were also examined [ 26 , 27 ], whereas the potential in vivo protective effect of antioxidants in the decocted extract of S. arabica is not yet explored. Psammomys obesus ( P. obesus ), Muridae , Gerbillidae is a desert gerbil of particular interest because, in its native habitat, P. obesus feeds on low-caloric vegetation remains healthy when in captivity and is subjected to nutritional stress induced by a high-calorie laboratory diet, resulting in the development of obesity, dyslipidemia, diabetes [ 28 ], and diabetic retinopathy [ 29 ].…”

Section: Introductionmentioning

confidence: 99%

Anti-Obesity and Anti-Dyslipidemic Effects of Salicornia arabica Decocted Extract in Tunisian Psammomys obesus Fed a High-Calorie Diet

Chrigui

Taieb

Jemai

et al. 2023

Foods

View full text Add to dashboard Cite

Salicornia is a halophyte plant that has been used in traditional medicine for the treatment of scurvy, goiter, and hypertension. It is commercialized in Europe and Asia as fresh salads, pickled vegetables, green salt, or tea powder. This work is the first to assess the potential anti-obesity and anti-dyslipidemic effects of Salicornia arabica decocted extract (SADE). SADE was characterized by its significant in vitro radical scavenging activity (using DPPH and ABTS assays). The effect of SADE on food intake, weight loss, serum biochemical parameters, liver and kidney weights, adiposity index and on liver histology was investigated in the Tunisian gerbil Psammomys obesus (P. obesus), which is recognized as a relevant animal model of human obesity and diabetes. P. obesus animals were firstly randomly divided into two groups: the first received a natural low-calorie chow diet (LCD), and the second group received a high-calorie diet (HCD) over 12 weeks. On day 90, animals were divided into four groups receiving or not receiving SADE (LCD, LCD + SADE, HCD, and HCD + SADE). If compared to the HCD group, SADE oral administration (300 mg/kg per day during 4 weeks) in HCD + SADE group showed on day 120 a significant decrease in body weight (−34%), blood glucose (−47.85%), serum levels of total cholesterol (−54.92%), LDL cholesterol (−60%), triglycerides (−48.03%), and of the levels of hepatic enzymes: ASAT (−66.28%) and ALAT (−31.87%). Oral administration of SADE restored the relative liver weight and adiposity index and significantly limited HCD-induced hepatic injury in P. obesus. SADE seems to have promising in vivo anti-obesity and anti-dyslipidemic effects.

show abstract

Section: Introductionmentioning

confidence: 99%

Anti-Obesity and Anti-Dyslipidemic Effects of Salicornia arabica Decocted Extract in Tunisian Psammomys obesus Fed a High-Calorie Diet

Chrigui

Taieb

Jemai

et al. 2023

Foods

View full text Add to dashboard Cite

show abstract

“…RBCs are nucleated in birds, reptiles, fish, and amphibians. These blood cells have been used in environmental studies stress [24][25][26][27][28][29][30], and to evaluate the response of xenobiotics in mammals [31][32][33]. However, hardly any studies have been published where environmental pollutants have been quantified in sea turtles [34,35].…”

Section: Introductionmentioning

confidence: 99%

Oxidative Stress Biomarkers in Erythrocytes of Captive Pre-Juvenile Loggerhead Turtles Following Acute Exposure to Methylmercury

et al. 2020

View full text Add to dashboard Cite

This study describes the use of erythrocytes (RBCs) of loggerhead turtles as in vitro models for evaluating their toxicity to methylmercury. Blood samples of loggerhead turtles that were born in the Colombian Caribbean were used. The LC50 of RBCs to methylmercury was determined at 96 h using methylmercury concentrations of 0.5–100 mg L−1. Next, the viability of the RBCs and the activity of the enzymes superoxide dismutase (SOD), glutathione S-transferase (GST), and lipid peroxidation by malondialdehyde (MDA) at 6 and 12 h of exposure to acute concentrations of 0, 1, and 5 mg L−1 were evaluated. The LC50 for loggerhead turtle RBCs was 8.32 mg L−1. The cell viability bioassay of RBCs exposed for 12 h only showed 100% cell viability. Increasing in vitro MeHg concentrations caused a corresponding increase in MDA concentration as well as decreases in the activities of SOD and GST. The RBCs represent an excellent model for ecotoxicological studies and SOD, GST, and MDA are biomarkers of environmental pollution and oxidative stress in loggerhead turtles. This was the first study conducted on loggerhead turtle where the response of RBCs to MeHg-induced oxidative stress is evaluated.

show abstract

Health risk assessment of heavy metals exposure via consumption of crops grown in phosphogypsum-contaminated soils

Chabchoubi

Bouguerra

Ksibi

et al. 2020

Environ Geochem Health

View full text Add to dashboard Cite

Antioxidant potential of Salicornia arabica lipid extract and their protective effect against cadmium induced oxidative stress in erythrocytes isolated from rats

Cited by 6 publications

References 33 publications

Anti-Obesity and Anti-Dyslipidemic Effects of Salicornia arabica Decocted Extract in Tunisian Psammomys obesus Fed a High-Calorie Diet

Anti-Obesity and Anti-Dyslipidemic Effects of Salicornia arabica Decocted Extract in Tunisian Psammomys obesus Fed a High-Calorie Diet

Oxidative Stress Biomarkers in Erythrocytes of Captive Pre-Juvenile Loggerhead Turtles Following Acute Exposure to Methylmercury

Health risk assessment of heavy metals exposure via consumption of crops grown in phosphogypsum-contaminated soils

Contact Info

Product

Resources

About