Antioxidant potential of hydrolysate-derived seahorse (Hippocampus abdominalis) peptide: Protective effects against AAPH-induced oxidative damage in vitro and in vivo

Lee, Hyo-Geun; Nagahawatta, D.P.; Yang, Fengqi; Jayawardhana, H.H.A.C.K.; Liyanage, N.M.; Lee, Daesung; Lee, Jeong Min; Yim, Mi‐Jin; Ko, Seok‐Chun; Kim, Ji-Yul; An, Hye Suck; Baek, Kwang Hyun; Jeon, You‐Jin; Kim, Hyunsoo

doi:10.1016/j.foodchem.2022.135130

Cited by 4 publications

(2 citation statements)

References 22 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Previous research has shown that AAPH exposure inhibits crucial cellular antioxidant enzymes such as catalase and superoxide dismutase (SOD), known for reducing ROS generation. Conversely, in Vero cells, the administration of hydrolysate‐derived seahorse peptide remarkably upregulated the expression levels of these enzymes, thereby effectively restoring the imbalanced antioxidant system 44 …”

Section: Resultsmentioning

confidence: 99%

See 1 more Smart Citation

Improving functional properties of rice protein isolates by hydrolysis using alcalase enzyme and assessing bioactivities of hydrolysates

Issac,

Banerjee,

Jamdar

2023

JSFA Reports

View full text Add to dashboard Cite

Background: Developing value-added products from rice grains is becoming increasingly significant to enhance productivity from excess rice grains. Therefore, the objective of this study was to improve the functional properties of rice protein from four rice varieties, namely, RRF-127, RRF-105, Swarna, and Protezin by enzymatic hydrolysis, and also to evaluate bioactivities like antioxidant, ACE, and DPP-IV inhibitory activities of the hydrolysates. Results:The alcalase hydrolysis increased protein solubility to >80% in the pH range of 4-10. The foaming capacity and stability of rice protein hydrolysates (RPHs) improved with the increase in pH. The hydrolysis significantly improved the emulsification activity index (EAI) in the pH range of 5-9. The hydrolysates showed antioxidant activity, namely, ABTS •+ radical scavenging, reducing power, and metal ion chelation. RRF-105 was found to possess the most potent antioxidant capacity among the hydrolysates.RPH could alleviate oxidative damage in erythrocytes, and their protective effects were concentration-dependent. The hydrolysates had stronger inhibition of ACE and DPP-IV enzymes. Protezin exhibited the highest ACE inhibition (63%), while Swarna demonstrated the most effective DPP-IV inhibition (66%). Conclusion:Hydrolysis with alcalase improved the functional and bioactive properties of rice proteins, indicating that RPH could serve as a source of bioactive peptides or as a functional ingredient with potential properties.

show abstract

Section: Resultsmentioning

confidence: 99%

“…Conversely, in Vero cells, the administration of hydrolysate-derived seahorse peptide remarkably upregulated the expression levels of these enzymes, thereby effectively restoring the imbalanced antioxidant system. 44…”

Section: Influence Of Protein Hydrolysates On Aaph-induced Hemolysis ...mentioning

confidence: 99%

Improving functional properties of rice protein isolates by hydrolysis using alcalase enzyme and assessing bioactivities of hydrolysates

Issac,

Banerjee,

Jamdar

2023

JSFA Reports

View full text Add to dashboard Cite

show abstract

Characterization and functional properties of umami peptides from douchi: Taste mechanism and antioxidant activity

Zhang,

Chen,

et al. 2024

Food Bioscience

View full text Add to dashboard Cite

Effect of ethanol treatment on the structural, techno-functional, and antioxidant properties of edible insect protein obtained from Tenebrio molitor larvae

Hoon Lee,

Kim,

Kim

et al. 2024

Food Chemistry

View full text Add to dashboard Cite

Antioxidant potential of hydrolysate-derived seahorse (Hippocampus abdominalis) peptide: Protective effects against AAPH-induced oxidative damage in vitro and in vivo

Cited by 4 publications

References 22 publications

Improving functional properties of rice protein isolates by hydrolysis using alcalase enzyme and assessing bioactivities of hydrolysates

Improving functional properties of rice protein isolates by hydrolysis using alcalase enzyme and assessing bioactivities of hydrolysates

Characterization and functional properties of umami peptides from douchi: Taste mechanism and antioxidant activity

Effect of ethanol treatment on the structural, techno-functional, and antioxidant properties of edible insect protein obtained from Tenebrio molitor larvae

Contact Info

Product

Resources

About