Antioxidant Potential of Centella asiatica-Associated Endophytic Bacteria

Rafat, Arash; Philip, Koshy; Muniandy, Sekaran

doi:10.1016/j.jbiotec.2010.09.870

Cited by 7 publications

(11 citation statements)

References 0 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…This is evident in the simultaneous presence of dihydroxyl and carboxyl groups in their aromatic rings 64 . Natural plant antioxidants can be classified into several main classes: phenolics (including flavonoids, anthocyanins, tannins, and phenolic acids), vitamins (such as tocopherols), ascorbic acid, and carotenoids 65 . Among these, phenolic acids (like rosmarinic, caffeic, chlorogenic, ferulic, p -coumaric, and vanillic acids) are known as natural antioxidants extensively present in medicinal plants.…”

Section: Resultsmentioning

confidence: 99%

Screening of 20 species from Lamiaceae family based on phytochemical analysis, antioxidant activity and HPLC profiling

Moshari-Nasirkandi,

Alirezalu,

Alipour

et al. 2023

Sci Rep

View full text Add to dashboard Cite

The Lamiaceae family encompasses numerous species highly valued for their applications in medicine, food, and cosmetics. In order to screen the Lamiaceae family and discover new sources of phytochemicals and antioxidants, we comprehensively evaluated 20 species from this family, including Phlomis herba-venti, P. tuberosa, P. olivieri, P. kurdica, Nepeta sp., N. cataria, N. saccharata, Stachys sp., S. inflata, Scutellaria albida, Marrubium parviflora, Mentha pulegium, Thymus kotschyanus, Lamium album, Salvia officinalis, S. multicaulis, S. macrochlamys, S. candidissima, S. verticillata, and S. nemorosa. The aerial parts of these species were analyzed to determine their total phenolic (TPC) and flavonoid (TFC) contents, total tannin content (TTC), ascorbic acid content (AAC), antioxidant capacity (assessed by FRAP and DPPH assays), and polyphenolic components (by HPLC). The phytochemical compounds and antioxidant properties varied widely among different species. The highest concentrations of TPC (70.93 mg GAE/g DW), TFC (17.89 mg Que/g DW), TTC (6.49 mg TAE/100 g), and AAC (1.15 mg AA/g DW), as well as the greatest antioxidant activity, were observed in different Salvia species. Additionally, chlorogenic and rosmarinic acids were the primary phenolic compounds identified in the extracts from the investigated Lamiaceae family. According to Hierarchical Cluster Analysis (HCA) and Principal Component Analysis (PCA), three groups of species were identified, characterized by variations in phytochemical composition and antioxidant capacity. The results obtained can provide new natural sources of phytochemicals and antioxidant agents, particularly from Salvia species, for the advancement of new products in the food, agricultural, cosmetics and health industries.

show abstract

Section: Resultsmentioning

confidence: 99%

Screening of 20 species from Lamiaceae family based on phytochemical analysis, antioxidant activity and HPLC profiling

Moshari-Nasirkandi,

Alirezalu,

Alipour

et al. 2023

Sci Rep

View full text Add to dashboard Cite

show abstract

“…This will allow identification of locally available vegetables that has antioxidant capability and developed into value added food. DPPH• scavenging assay is widely used in measuring antioxidant capacity due to its simplicity, rapid and sensitivity (Prior et al, 2005;Rafat et al, 2010). The DDPH assay shows that although the some vegetable samples shared the same genus but the performance in DPPH• scavenging is different (Table 1).…”

Section: Resultsmentioning

confidence: 99%

In Vitro Bioactivities and Phytochemicals Content of Vegetables From Sabah, Malaysia

A. G.,

E.,

How

2016

BSJ

View full text Add to dashboard Cite

This study aims to investigate potential of vegetables from Sabah with value-added benefits in nutraceuticals. Fifty-five samples of vegetables were collected from local market and tested for antioxidant activity using DPPH assay. Four species with high DPPH scavenging activity (>80%) which are Cosmos caudatus, Eryngium foetidum, Ipomoea batatas and Manihot esculenta Crantz were selected and subjected to different solvents extraction and tested to different scavenging assays (DPPH, O2 and NO), protein kinase-phosphatase assay (GSK-3β, MKK1, and MSG5) and antibacterial tests. Ethanol extract of I. batatas (90.56%), boiled water extract of M. esculenta Crantz (62.77%) and extractable polyphenol extract of E. foetidum (50.93%) exhibits comparable scavenging activities to catechin for DPPH, O2 and NO, respectively. Polyphenols, phenolic acids, flavonoids and proanthocynidins are detected in all extracts at concentration between 0.001 mg/g to 0.52 mg/g. The highest total polyphenols content (0.40±0.01 mg GAE/g), total phenolics content (0.52±0.01 mg GAE/g), total flavonoids content (0.13±0.01 mg CE/g) and total proanthocyanidins content (0.12±0 mg CE/g) were obtained in extractable polyphenols of Cosmos caudatus. No extracts were observed as inhibitor for GSK-3β, MKK1 and MSG5. Inhibition of Pseudomonas aeruginosa (8.0 mm to 12.3 mm) was only obtained in extractable polyphenols and ethanol extracts. Extractable polyphenols of E. foetidum exhibit the largest inhibition of Pseudomonas aeruginosa (12.3 mm).

show abstract

“…In most plant extracts, there is a positive correlation between antioxidant activity and the amount of polyphenolic compounds [76,77]. However, some studies have reported that there is no positive relationship between the polyphenolic compounds and their antioxidant activities [78,79]. Te total phenolic and favonoid content of the DCM stem bark extract of F. sycomorus was lower than that of the leaf extract of S. henningsii at all the tested concentrations.…”

Section: Discussionmentioning

confidence: 99%

Phytochemical Screening and In Vitro Evaluation of the Antioxidant Potential of Dichloromethane Extracts of Strychnos henningsii Gilg. and Ficus sycomorus L.

Wafula

Mworia

Ngugi

2023

The Scientific World Journal

View full text Add to dashboard Cite

Medicinal plants are a rich source of antioxidants such as flavonoids, phenols, tannins, and alkaloids among others and are currently used as alternative and complementary drugs in the management of stress-related disorders. Strychnos henningsii and Ficus sycomorus have been traditionally used by the people of Mbeere, Embu county, Kenya, as medicine for the treatment of various oxidative stress-related disorders such as diabetes and rheumatism; however, no empirical data are available to authenticate the said claim. The aim of this study was to evaluate preliminary phytochemical screening and in vitro antioxidant activity of dichloromethane (DCM) leaf extract of S. henningsii and stem bark extract of F. sycomorus using DPPH, hydrogen peroxide, and ferric reducing power assays; total flavonoids and phenolic compounds were also determined by colorimetric assay and Folin–Ciocalteu reaction, respectively. Phytochemical screening showed that both extracts possessed saponins, flavonoids, phenols, steroids, alkaloids, and cardiac glycosides; however, terpenoids were found to be absent in S. henningsii. The total phenolic and flavonoid content of the DCM stem bark extract of F. sycomorus was lower than that of the leaf extract of S. henningsii. These extracts significantly exhibited strong antioxidant activities at different concentrations tested. The IC50 values of S. henningsii and F. sycomorus were 0.325 mg/ml and 0.330 mg/ml for hydrogen peroxide and 0.068 mg/ml and 0.062 mg/ml for DPPH, respectively. Both DCM leaf and stem bark extracts of S. henningsii and F. sycomorus were found to have strong ferric reducing power. Therefore, both extracts showed significant nonenzyme-based antioxidant activities. The two plants possess phytochemicals that have significant antioxidant properties.

show abstract

Antioxidant Potential of Centella asiatica-Associated Endophytic Bacteria

Cited by 7 publications

References 0 publications

Screening of 20 species from Lamiaceae family based on phytochemical analysis, antioxidant activity and HPLC profiling

Screening of 20 species from Lamiaceae family based on phytochemical analysis, antioxidant activity and HPLC profiling

In Vitro Bioactivities and Phytochemicals Content of Vegetables From Sabah, Malaysia

Phytochemical Screening and In Vitro Evaluation of the Antioxidant Potential of Dichloromethane Extracts of Strychnos henningsii Gilg. and Ficus sycomorus L.

Contact Info

Product

Resources

About