Antioxidant potential and content of the polyphenolic secondary metabolites of white rot macrofungi; Flavodon flavus (Klotzsch.) and Xylaria feejeensis (Berk.)

Fernando, M. D.; Wijesundera, R. C.; Soysa, S.S.S.B.D.P.; Silva, ED de; Nanayakkara, C.M.

doi:10.25177/jps.1.1.2

Cited by 3 publications

(4 citation statements)

References 5 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…versicolor culture filtrate particularly active in inhibiting aflatoxins (fraction A), [ 36 ]. Fungal secretome is essentially composed of polysaccharides, proteins (glycosylated and not, with enzymatic or different activities), polyphenols and small metabolites [ 37 – 40 ]. In relation to this, considering the fraction A as essentially free from polyphenols, small metabolites and small peptides [ 36 ], we separated fractions enriched with polysaccharides or proteins.…”

Section: Resultsmentioning

confidence: 99%

Tramesan, a novel polysaccharide from Trametes versicolor. Structural characterization and biological effects

et al. 2017

View full text Add to dashboard Cite

Mushrooms represent a formidable source of bioactive compounds. Some of these may be considered as biological response modifiers; these include compounds with a specific biological function: antibiotics (e.g. plectasin), immune system stimulator (e,g, lentinan), antitumor agents (e.g. krestin, PSK) and hypolipidemic agents (e.g. lovastatin) inter alia. In this study, we focused on the Chinese medicinal mushroom “yun zhi”, Trametes versicolor, traditionally used for (cit.) “replenish essence and qi (vital energy)”. Previous studies indicated the potential activity of extracts from culture filtrate of asexual mycelia of T. versicolor in controlling the growth and secondary metabolism (e.g. mycotoxins) of plant pathogenic fungi. The quest of active principles produced by T. versicolor, allowed us characterising an exo-polysaccharide released in its culture filtrate and naming it Tramesan. Herein we evaluate the biological activity of Tramesan in different organisms: plants, mammals and plant pathogenic fungi. We suggest that the bioactivity of Tramesan relies mostly on its ability to act as pro antioxidant molecule regardless the biological system on which it was applied.

show abstract

Section: Resultsmentioning

confidence: 99%

Tramesan, a novel polysaccharide from Trametes versicolor. Structural characterization and biological effects

et al. 2017

View full text Add to dashboard Cite

show abstract

“…The antioxidant properties of terrestrial Flavodon flavus ( F. flavus ) and Xylaria feejeensis ( X. feejeensis ), harvested from the dry zone forest from Sri Lanka were investigated by Fernando et al (2016) . The study also aimed to determine the contribution of phenolic and flavonoid substances to the antioxidant capabilities of these white rot fungi.…”

Section: Biologically Active Secondary Metabolites Produced By White-...mentioning

confidence: 99%

“…White rot fungi possess a significant capacity to produce numerous enzymes and secondary metabolites, exhibiting potential in the fields of nutrition, medicine, and degradation. These secondary metabolites, including terpenoids, polyphenols, sterols, flavonoids, alkaloids, derivatives of benzoic acid, quinolones, anthraquinones, and lactones possess bioactive characteristics ( Jaszek et al, 2013 ; Jaszek et al, 2014 ; Fernando et al, 2016 ; Bogale, 2020 ; Kundu and Khan, 2021 ; Mahuri et al, 2023 ). Moreover, considering the economic significance and the intention of applications based on biologically active secondary metabolites, there has been a rising global interest in these compounds produced by white rot fungi.…”

Section: Introductionmentioning

confidence: 99%

Biologically active secondary metabolites from white-rot fungi

Pinar,

Rodríguez-Couto

2024

Front. Chem.

View full text Add to dashboard Cite

In recent years, there has been a considerable rise in the production of novel metabolites derived from fungi compared to the ones originating from bacteria. These organic substances are utilized in various sectors such as farming, healthcare, and pharmaceutical. Since all dividing living cells contain primary metabolites, secondary metabolites are synthesized by utilizing intermediate compounds or by-products generated from the primary metabolic pathways. Secondary metabolites are not critical for the growth and development of an organism; however, they exhibit a variety of distinct biological characteristics. White-rot fungi are the only microorganisms able to decompose all wood components. Hence, they play an important role in both the carbon and nitrogen cycles by decomposing non-living organic substrates. They are ubiquitous in nature, particularly in hardwood (e.g., birch and aspen) forests. White-rot fungi, besides ligninolytic enzymes, produce different bioactive substances during their secondary metabolism including some compounds with antimicrobial and anticancer properties. Such properties could be of potential interest for the pharmaceutical industries. Considering the importance of the untapped biologically active secondary metabolites from white-rot fungi, the present paper reviews the secondary metabolites produced by white-rot fungi with different interesting bioactivities.

show abstract

“…: Armillaria mellea, Bjerkandera adusta, Botrytis [64,65], a także nieliczne workowce (Ascomycota), m.in. Daldinia concentrica, Xylaria polymorpha [66], Xylaria feejeensis [67], Xylaria hypoxylon [68].…”

Section: Ogólna Charakterystykaunclassified

Pozostałości Substancji Farmakologicznie Czynnych Jako Zanieczyszczenie Środowiska I Rola Grzybów Białej Zgnilizny W Ich Usuwaniu

Kózka¹,

Bębas²

2021

pps

View full text Add to dashboard Cite

Obecność substancji czynnych leków w środowisku stanowi poważny problem dotyczący całego świata. Wśród związków o zastosowaniu terapeutycznym zanieczyszczających otoczenie można znaleźć przedstawicieli różnych grup substancji farmakologicznych, a w szczególności: niesteroidowych leków przeciwzapalnych, antybiotyków i innych związków biobójczych, steroidów oraz związków stosowanych w terapii schorzeń ośrodkowego układu nerwowego lub układu krwionośnego. Zanieczyszczenie takimi substancjami wynika z nieprzystosowania konwencjonalnych oczyszczalni ścieków do ich usuwania. Związki te wraz z oczyszczonymi ściekami trafiają do środowiska, gdzie stanowią zagrożenie dla organizmów (w tym człowieka), zaburzając jednocześnie ekosystemy. Z tego powodu poszukiwane są nowe metody usuwania substancji czynnych leków ze ścieków komunalnych. Jednym z nich jest zastosowanie nietaksonomicznej grupy grzybów białej zgnilizny, których zdolności do rozkładu różnych związków zostały potwierdzone w licznych badaniach. Niniejsza praca stanowi przegląd przyczyn obecności substancji czynnych leków w środowisku, związków obecnych w ściekach, ich toksycznego wpływu na organizmy, regulacji prawnych dotyczących obecności związków farmakologicznych w środowisku oraz zdolności grzybów białej zgnilizny do rozkładu substancji o znaczeniu terapeutycznym.

show abstract

Antioxidant potential and content of the polyphenolic secondary metabolites of white rot macrofungi; Flavodon flavus (Klotzsch.) and Xylaria feejeensis (Berk.)

Cited by 3 publications

References 5 publications

Tramesan, a novel polysaccharide from Trametes versicolor. Structural characterization and biological effects

Tramesan, a novel polysaccharide from Trametes versicolor. Structural characterization and biological effects

Biologically active secondary metabolites from white-rot fungi

Pozostałości Substancji Farmakologicznie Czynnych Jako Zanieczyszczenie Środowiska I Rola Grzybów Białej Zgnilizny W Ich Usuwaniu

Contact Info

Product

Resources

About