Introduction:The Present article is an empirical investigation of the traditional health seeking practice among the tribal people of North Chhattisgarh of India. It is an attempt to explore the traditional healing practice and traditional knowledge system of the medicinal plant species utilized by traditional healers of North Chhattisgarh for the treatment of chronic fever. Objective: The objective of the present research is to discover and analyses the traditional medicinal practice to cure chronic fever and to find out the phytochemical and medicinal properties of traditional medicine among the tribal of North Chhattisgarh, India for curing chronic fever. Methodology: The traditional healers among the various tribes of North Chhattisgarh were chosen as key informants by using purposive sampling techniques from Raigarh and Korba district of Chhattisgarh, India. The intensive interview was taken to the selected traditional healer by using the interview guide and focused group discussion (FGD). Result: Total 25 medicinal plants and 11 type of medicine are being used for the treatment of chronic fever by the tribal healers of North Chhattisgarh. The quantum of used herbs, method of preparation, direction of use of medicine, and prohibition during medication are discussed in present article. The medico-religious practices are also described in this article which is used to treat chronic fever. The phytochemical and medicinal properties of the medicinal plants which are used for curing chronic fever are find out with the help of earlier published sources. Most of the medicinal plants which have been used for curing of chronic fever are showed appropriate phytochemical and medicinal properties. Conclusion: Present article explores abundance of traditional knowledge on medicinal plants and magico-religious belief which are responsible in treating chronic fever among the tribal and it also shows the trust and relation between nature and tribal hence it can be concluded that knowledge of medicine related with plants and spiritual practice is a part of folk medicine or ethno-medicine, on the basis of above mentioned data described in present article, it can infer that folk medicinal knowledge among tribal of North Chhattisgarh is eventually rich and commendable even though considered as backward socio-economic ethnic groups, hence medicinal plants represented in present article should be given a scientific recognition by executing phytochemical, pharmacological and molecular test and with those results it should be introduced as a drug to cure chronic fever and accompanying with this, royalty should be given to the tribal of these medicine and therefore further studies in this topic appear necessary.