Antioxidant, larvicidal and antiacetylcholinesterase activities of cashew nut shell liquid constituents

Oliveira, Micheline Soares Costa; Morais, Selene Maia de; Magalhães, Davi Varela; Batista, Williams Pereira; Vieira, Ícaro Gusmão Pinto; Craveiro, A. A.; Manezes, Jane Eire Silva Alencar de; Carvalho, Ana Fontenele Urano; Lima, Glauber Pacelli Gomes de

doi:10.1016/j.actatropica.2010.08.003

Cited by 87 publications

(65 citation statements)

References 28 publications

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“…The solvent used can contribute to the variation between the fractions since it has been reported that the extraction of active biochemical compounds from plants depends upon the polarity of the solvents used [8]. A number of studies have reported the larvicidal potential of A. occidentale supporting the results gathered in the study [14,15].…”

Section: Thin-layer Chromatographic (Tlc) Fingerprinting/profilingsupporting

confidence: 76%

“…A study was conducted on the antioxidant, larvicidal and anti-acetylcholinesterase activities of cashew nut shell liquid constituents namely, cardol, cardanol and anacardic acid. Results of study indicated that these constituents showed good larvicidal activity against A. aegypti [15]. Another study reported that the A. aegypti was found to be highly susceptible to cashew nut shell liquid against the immature stages of two mosquitos, A. aegypti and Anopheles subpictus.…”

Section: Resultsmentioning

confidence: 91%

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Larvicidal and ovicidal activities, characterization and stability of Anacardium occidentale (Cashew) shell wastes

Torres¹,

Garbo²,

Walde³

2017

Virol Res Rev

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Dengue and zika continue to be the most rapidly emerging febrile diseases and pose a negative impact on social and economic activity of the country. Despite of recent innovation in dengue vaccine, eradication of the vector, Aedes aegypti, is still the best way to inhibit dengue and zika outbreaks. In this study, we evaluated the larvicidal and ovicidal activities and characterized the shell wastes of Anacardium occidentale including its stability for a period of two (2) years. The shell wastes were extracted using 95% EtOH and n-hexane and were bio-assayed for larvicidal and ovicidal activities against A. aegypti following the WHO standard bioassay method. The mortality was observed 24 and 48 hours after treatment and data were subjected to probit analysis to determine lethal concentrations (LC 50 and LC 90 ). The ethanol extract was characterized by thin-layer chromatography (TLC) and phytochemical analysis.

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Section: Thin-layer Chromatographic (Tlc) Fingerprinting/profilingsupporting

confidence: 76%

Section: Resultsmentioning

confidence: 91%

Larvicidal and ovicidal activities, characterization and stability of Anacardium occidentale (Cashew) shell wastes

Torres¹,

Garbo²,

Walde³

2017

Virol Res Rev

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“…The chemical composition found in this study was different from the earlier reported in literatures [16,19]. There may be effects due to extraction processes, climate conditions and the origin of the nuts.…”

Section: Discussioncontrasting

confidence: 55%

“…CNSL has been already reported in some literature as: natural anti-inflammatory [18], antioxidant [19], antifungal [20], larvicidal [16], antitumor [21,22], anticholinesterase [23], non-mutagenic in mice [24] lipoxygenase [25] and xanthine oxidase inhibitory [19,26] activities.…”

Section: Introductionmentioning

confidence: 99%

“…The CNSL may be classified according to the methodology of obtaining, in: CNSL in nature (iCNSL) and technical CNSL (tCNSL) [15]. According to Oliveira et al [16], the iCNSL comprises anacardic acid (62.9%); cardol (23.98%) and cardanol (6.99%), while tCNSL, extracted at 80-200º C comprises of cardanol by 52-60%, cardol and polymeric materials by 10% and 30%, respectively [17].…”

Section: Introductionmentioning

confidence: 99%

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Net effects of cashew nuts in Saccharomyces cerevisiae front to damage induced by hydrogen peroxide

Leite¹,

Gomes²,

Oliveira³

et al. 2016

Int Arch Med

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Cellular injury associated with oxidative stress has been related in the etiology and progression of many diseases, including neurodegenerative diseases and cancer. Shell of cashew nut releases the alkylphenols oil, known as cashew nut shell liquid (CNSL), which can be characterized according to the method of production such as technical (tCNSL) and in natural (iCNSL) types. This study aimed to characterize the chemical constituents in both liquids by gas chromatography coupled to mass spectrometry (GC-MS), and to evaluate the net effect of them in proficient (SODWT) and deficient (Sod1∆, Sod2∆, Cat1∆, Sod1∆Sod2∆, Sod1∆Cat1∆) Saccharomyces cerevisiae oxidative damaged induced by hydrogen peroxide (H 2 O 2 (10 mM); stressor) at concentrations of 17.37, 34.7 and 69.5 µg/ml in pre-, co-and post-treatment. Both iCNSL and tCNSL produced no oxidizing effect to the tested yeast strains, otherwise they protected against damage induced by stressor (STR). However, tCNSL was found more prominent than the iCNSL in restorative activity. In conclusion, CNSLs (iCNSL/tCNSL) exhibited excellent protective, antioxidant and repair capabilities compared to the damage induced by STR in S. cerevisiae cells, thus may be a suggestion for its biotechnological production especially for pharmaceutical account.

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Phytochemical profiling, antioxidant activities, enzymatic activities and insecticidal potential of aqueous extracts of four plants on the larvae of Helicoverpa armigera (Lepidoptera: Noctuidae), the main pest of cotton plant in Ivory Coast

Bini

Kobenan

Kouakou

et al. 2023

Arch Insect Biochem Physiol

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In the context of climate change, the Ivorian cotton industry is facing with the loss of sensitivity of pests (Helicoverpa armigera) and the appearance of new so‐called emerging insects. Faced with this situation, cotton producers tend to use insecticide products in high doses, in excess of the norm. However, the misuse of chemical products poses many health risks. Therefore, to limit the use of chemicals, aqueous extracts of local plants with insecticidal properties were examined in the laboratory and in the field. Four local plant species were selected [Anacardium occidentale (Anarcardier); Azadirachta indica (Neem); Hyptis suaveolens (Hyptis) and Tephrosia vogelii (Tephrosia)]. After determining the chemical profiles of the four extracts by high performance liquid chromatography (HPLC)‐mass spectrometry, their inhibitory activities were assessed in cholinesterase and tyrosinase. The sensitivity of Helicoverpa armigera larvae was evaluated by ingesting the aqueous extracts at several concentrations ranging from 2% to 64% in an artificial nutrient substrate. Then, the mortality rates of the larvae during 72 h were evaluated and the lethal concentrations were determined. The results of chemical analyses (HPLC) showed that the richest aqueous extract in phytochemicals with 54 elements detected was that of cashew (A. occidentale). T. vogelii, A. indica and H. suaveolens presented 44, 45, and 39 chemical compounds, respectively. In addition, the total phenolic content was higher in A. occidentale (110.67 mg gallic acid equivalents/g) followed by A. indica (42.43 mg gallic acid equivalents/g). The highest antioxidant ability was observed with the aqueous extract of cashew (A. occidentale). Anti‐enzymatic activities such as acetylcholinesterase, butyrylcholinesterase and tyrosinase inhibition were most pronounced in A. occidentale (2.35 ± 0.02 mg galanthamine equivalent/g, 3.77 ± 0.01 mg galanthamine equivalent/g and 71.28 ± 0.07 mg kojic acid equivalent/g, respectively). The most toxic aqueous extract for H. armigera larvae was that of cashew with a lethal concentration LC50 = 11.68%. Moreover, the principal component analysis performed showed that the insecticidal activity is strongly correlated with the antioxidant and enzymatic activities of the aqueous extracts. Then, the hierarchical ascending classification showed cashew as the best plant. For the sustainability of cotton production, it would be necessary to limit the use of chemical‐synthetic insecticides through the use of plant extracts, especially from cashew leaves.

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Antioxidant, larvicidal and antiacetylcholinesterase activities of cashew nut shell liquid constituents

Cited by 87 publications

References 28 publications

Larvicidal and ovicidal activities, characterization and stability of Anacardium occidentale (Cashew) shell wastes

Larvicidal and ovicidal activities, characterization and stability of Anacardium occidentale (Cashew) shell wastes

Net effects of cashew nuts in Saccharomyces cerevisiae front to damage induced by hydrogen peroxide

Phytochemical profiling, antioxidant activities, enzymatic activities and insecticidal potential of aqueous extracts of four plants on the larvae of Helicoverpa armigera (Lepidoptera: Noctuidae), the main pest of cotton plant in Ivory Coast

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