Antioxidant effects of ovotransferrin and its hydrolysates

Kim, J.; Moon, Sang-Ho; Ahn, Dong U.; Paik, Hyun‐Dong; Park, E.

doi:10.3382/ps.2012-02150

Cited by 40 publications

(39 citation statements)

References 48 publications

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“…A comparative examination of the antioxidant characteristics of hen's otrf (and its hydrolysed peptides) and superoxide anion scavenging activity revealed the former to be around 3.2–13.5 times greater [35]. Moreover, otrf-derived peptides displayed synergistic antioxidant impacts associated with vitamin C, epigallocatechin gallate, and caffeic acid [36].…”

Section: Characteristics Of Ovotransferrinmentioning

confidence: 99%

The Utility of Ovotransferrin and Ovotransferrin‐Derived Peptides as Possible Candidates in the Clinical Treatment of Cardiovascular Diseases

Chen

Jiang

Peng

et al. 2017

Oxidative Medicine and Cellular Longevity

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Several of the most prevalent etiological factors which contribute towards global death rates are associated with cardiovascular diseases (CVDs), which include a range of conditions such as angina, rheumatic heart disease, and venous thrombosis. Extensive research has been conducted into the role played by oxidative stress and inflammation in the functional transformations associated with the progression of CVDs, while the research findings from these investigations have been both fruitful and informative. In view of the adverse secondary effects that result from the clinical administration of many synthetic medications, research which explored the treatment of severe and long-lasting conditions, including CVDs, has primarily centered on the potential benefits displayed by natural agents, one of which is food protein-based bioactive peptides. Most importantly, previous research has revealed the possible benefits associated with these products' anti-inflammatory and antioxidant characteristics. In light of these considerations, this paper aims to review the degree to which ovotransferrin (otrf, also referred to as conalbumin) and otrf-derived peptides, including IRW, IQW, and KVREGT, are, by virtue of their anti-inflammatory and antioxidant characteristics, viable treatment agents for endothelial dysfunction and the prevention of CVD.

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Section: Characteristics Of Ovotransferrinmentioning

confidence: 99%

The Utility of Ovotransferrin and Ovotransferrin‐Derived Peptides as Possible Candidates in the Clinical Treatment of Cardiovascular Diseases

Chen

Jiang

Peng

et al. 2017

Oxidative Medicine and Cellular Longevity

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“…Kim and coworkers [ 51 ] demonstrated that the antioxidant effects of hen’s ovotransferrin and of its hydrolyzed peptides is approximately 3.2–13.5 times higher than superoxide anion scavenging activity than Otrf, with the maximum activity displayed by octapeptides. Similar results were obtained for oxygen radical absorbance capacity assay and against the oxidative stress-induced DNA damage in human leukocytes [ 51 ]. In addition, Otrf-derived peptides showed synergistic antioxidant effects with Vitamin C, epigallocatechin gallate (EGCG), and caffeic acid [ 52 ].…”

Section: Antioxidant Activity Of Ovotransferrin and Its Peptidesmentioning

confidence: 99%

The Nutraceutical Properties of Ovotransferrin and Its Potential Utilization as a Functional Food

et al. 2015

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Ovotransferrin or conalbumin belong to the transferrin protein family and is endowed with both iron-transfer and protective activities. In addition to its well-known antibacterial properties, ovotransferrin displays other protective roles similar to those already ascertained for the homologous mammalian lactoferrin. These additional functions, in many cases not directly related to iron binding, are also displayed by the peptides derived from partial hydrolysis of ovotransferrin, suggesting a direct relationship between egg consumption and human health.

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“…Functional peptides are not active within the sequence of the parent protein molecule and can be released by in vivo or in vitro processes [8]. The main procedure for obtaining bioactive peptides from food products is enzymatic hydrolysis of proteins orchestrated with the use of various enzymes of microbial, plant or animal origin [9], although chemical hydrolysis [10] or processing technologies such as heat or high-intensity pulsed electric field treatments can also be applied [11,12].…”

Section: Introductionmentioning

confidence: 99%

Chicken Egg Proteins and Derived Peptides with Antioxidant Properties

Benedé

Molina

2020

Foods

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In addition to their high nutritional value, some chicken egg proteins and derivatives such as protein hydrolysates, peptides and amino acids show antioxidant properties which make them prominent candidates for the development of functional foods, drawing attention to both the food and biopharmaceutical industries. This review summarizes current knowledge on antioxidant activity of chicken egg proteins and their derived peptides. Some egg proteins such as ovalbumin, ovotransferrin and lysozyme from egg white or phosvitin from yolk have shown antioxidant properties, although derived peptides have higher bioactive potential. The main process for obtaining egg bioactive peptides is enzymatic hydrolysis of its proteins using enzymes and/or processing technologies such as heating, sonication or high-intensity-pulsed electric field. Different in vitro assays such as determination of reducing power, DPPH and ABTS radical-scavenging activity tests or oxygen radical absorbance capacity assay have been used to evaluate the diverse antioxidant mechanisms of proteins and peptides. Similarly, different cell lines and animal models including zebrafish, mice and rats have also been used. In summary, this review collects all the knowledge described so far regarding egg proteins and derived peptides with antioxidant functions.

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Antioxidant effects of ovotransferrin and its hydrolysates

Cited by 40 publications

References 48 publications

The Utility of Ovotransferrin and Ovotransferrin‐Derived Peptides as Possible Candidates in the Clinical Treatment of Cardiovascular Diseases

The Utility of Ovotransferrin and Ovotransferrin‐Derived Peptides as Possible Candidates in the Clinical Treatment of Cardiovascular Diseases

The Nutraceutical Properties of Ovotransferrin and Its Potential Utilization as a Functional Food

Chicken Egg Proteins and Derived Peptides with Antioxidant Properties

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