Antioxidant effect of propolis against exposure to chromium inCyprinus carpio

Abstract

The aim of the present study was to investigate the ameliorative properties of propolis against the toxic effects of chromium (VI) by examining oxidative damage markers such as lipid peroxidation and the antioxidant defence system components in carp (Cyprinus carpio). The fish were exposed to sublethal concentrations of chromium. Propolis was simultaneously administered to chromium-exposed fish. Treatment was continued for 28 days, and at the end of this period, blood and tissue (liver, kidney, spleen, and gill) samples were collected. Levels of malondialdehyde (MDA) and reduced glutathione (GSH) as well as superoxide dismutase (SOD), catalase (CAT), and glutathione peroxidase (GSH-Px) activities were determined in blood and tissues for measurement of oxidant-antioxidant status. The levels of MDA, as an index of lipid peroxidation, increased in blood and tissues. Antioxidant enzyme activities in blood and tissues were modified in chromium groups compared to controls. Simultaneous administration of propolis ameliorated these parameters. The present results suggest that administration of propolis might alleviate chromium-induced oxidative stress.

Ameliorative effect of propolis and nanopropolis supplementation against oxidative stress induced by Microcystis aeruginosa in Oreochromis niloticus

“…On the other hand, Tilapia fed the diet containing propolis nanoparticles and propolis combined with M. aeruginosa cells supplementation showed significant increment in the studied antioxidant activity levels and decrement in MDA level, respectively compared to (group 4) fish fed on diet mixed with M. aeruginosa cells only. These results are in cope with, (Yonar et al, 2014) who reported that simultaneous treatment with propolis decreased the severity of the oxidative stress induced by chromium in different tissues of common carp. (Zegura et al, 2011).…”

Simvastatin attenuates chromium-induced nephrotoxicity in rats

“…We also found that the exposure of rats to Na (2) Cr(2)O(7) for 8 consecutive days provoked renal damages with a significant increase in kidney MDA. Accordingly, Yonar et al reported that the levels of MDA, as an index of lipid peroxidation, increased as well as reduced GSH levels in Cyprinus carpio kidney treated with chromium (19). …”

Toxic Effects of Chronic Chlorpyrifos Exposure on Jejunum of Adult Male Albino Rats and the Possible Ameliorative Role of Propolis

“…Also, Yonar et al (2014) considered CPF exposure to as a stressor substance. In addition, Mazzon et al (2002) found that stress disrupts intestinal homeostasis and increase the intestinal permeability in rats.…”

“…Also, Attia et al (2012) stated that CPF treatment for 70 days cause significant reduction in antioxidant enzyme activities and elevation in lipid peroxidation level. In addition, Yonar et al (2014) stated that Lipid peroxidation is the initial step of cellular membrane damage.…”