Antioxidant Components as Potential Neuroprotective Agents in Sesame (<i>Sesamum indicum</i>L.)

Park, Si-Hyung; Ryu, Su-Noh; Bu, Youngmin; Kim, Ho-Cheol; Simon, James E.; Kim, Kwan-Su

doi:10.1080/87559120903564464

Cited by 40 publications

(24 citation statements)

References 129 publications

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“…In contrast, a gradual increase of the SMG level was observed throughout the entire time course of reaction. These results suggested that sesaminol could be successfully prepared by the enzymatic hydrolysis of STG with β-glucosidase and cellulase, which was consistent with the previous studies [1,[20][21][22].…”

Section: Determination and Identification Of Sesaminol Triglucoside Hsupporting

confidence: 92%

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Preparation of Sesaminol from Sesaminol Triglucoside by β‐Glucosidase and Cellulase Hydrolysis

Peng

Meng

et al. 2016

J Americ Oil Chem Soc

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Sesaminol triglucoside (i.e., 2,6‐O‐di(β‐d‐glucopyranosyl)‐β‐d‐glucopyranosyl sesaminol, STG) is a physiologically active substance obtained abundantly from defatted sesame cake. Since, the industrial preparation of sesaminol from STG has not been reported previously, the aim of this research was to prepare sesaminol by hydrolysis of STG using β‐glucosidase and cellulase. Under the optimal conditions of total enzyme dosage 100 μL (8,000.72 U), the ratio of β‐glucosidase and cellulase 20:80 (v/v) (0.72:8,000, U/U), reaction time 24 h, substrate concentration 6 mg/mL, reaction temperature 50 °C, and reaction system pH 4.8, the yield of sesaminol was 48.9 %. Further, sesaminol and other hydrolysis products (sesaminol diglucoside and sesaminol monoglucoside) were successfully determined by high performance liquid chromatography and electrospray ionization/mass spectrometry.

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Section: Determination and Identification Of Sesaminol Triglucoside Hsupporting

confidence: 92%

“…Sesame seed (Sesamum indicum L.) has always been an oilseed of great importance worldwide, and it is rich in various bioactive furofuran lignans, particularly sesamin, sesamol, sesamolinol and sesaminol glucosides [1], which play many essential roles in human health due to…”

Section: Introductionmentioning

confidence: 99%

Preparation of Sesaminol from Sesaminol Triglucoside by β‐Glucosidase and Cellulase Hydrolysis

Peng

Meng

et al. 2016

J Americ Oil Chem Soc

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“…The mechanism and pathway of sesaminol and sesamol formation from sesamolin have not been well elucidated 25. According to previous reports 8, 26, the entire reaction process in the reaction system here might be described by following the pathways (Fig.…”

Section: Resultsmentioning

confidence: 86%

A novel conversion of sesamolin to sesaminol by acidic cation exchange resin

Huang

Song

Zhang

et al. 2012

Euro J Lipid Sci & Tech

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Sesame (Sesamum indicum L.) seed and its oil contain abundant lignans, including sesamin, sesamolin, sesamol, sesaminol, and their glycosides. In the present study, a novel reaction pathway, using an anhydrous solvent system, cation exchange resin catalyst, and HPLC for detection, was employed for the conversion of sesamolin into sesaminol. Under optimal conditions of 5 mL toluene, 908C, initial sesamolin concentration of 6 mM, and catalyst dosage of 16.66 g/mmol of sesamolin, a 75.0% yield of sesaminol was achieved. The reaction mechanism was inferred to be that of a Friedel-Crafts reaction, with the catalyst showing remarkable catalytic activity and producing only slightly decreased yield after reuse in five subsequent batches. Owing to excellent reusability, low cost, and ready availability, this catalyst provides a very satisfactory option for converting sesamolin to sesaminol.Practical applications: Sesaminol is a potential natural antioxidant for use as a food additive and in medicinal applications, but it is a naturally occurring trace compound, and could be transformed from sesamolin under proper, specific conditions. The cation exchange resin 732 provides a satisfactory option for catalyzing the conversion of sesamolin into sesaminol. This suggests encouraging prospects for practical or industrial applications utilizing its notable catalytic performance, reusability, low cost, and easy availability.

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“…Under different heating conditions, it can be transformed to sesamol and other products . The transformations of lignans during the oil production process are shown in Fig. .…”

Section: Important Antioxidant Components In Sesame Seed Oilmentioning

confidence: 99%

The relationship of antioxidant components and antioxidant activity of sesame seed oil

et al. 2015

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Although sesame seed oil contains high levels of unsaturated fatty acids and even a small amount of free fatty acids in its unrefined flavored form, it shows markedly greater stability than other dietary vegetable oils. The good stability of sesame seed oil against autoxidation has been ascribed not only to its inherent lignans and tocopherols but also to browning reaction products generated when sesame seeds are roasted. Also, there is a strong synergistic effect among these components. The lignans in sesame seed oil can be categorized into two types, i.e. inherent lignans (sesamin, sesamolin) and lignans mainly formed during the oil production process (sesamol, sesamolinol, etc.). The most abundant tocopherol in sesame seed oil is γ-tocopherol. This article reviews the antioxidant activities of lignans and tocopherols as well as the browning reaction and its products in sesame seed and/or its oil. It is concluded that the composition and structure of browning reaction products and their impacts on sesame ingredients need to be further studied to better explain the remaining mysteries of sesame oil.

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Antioxidant Components as Potential Neuroprotective Agents in Sesame (Sesamum indicumL.)

Cited by 40 publications

References 129 publications

Preparation of Sesaminol from Sesaminol Triglucoside by β‐Glucosidase and Cellulase Hydrolysis

Preparation of Sesaminol from Sesaminol Triglucoside by β‐Glucosidase and Cellulase Hydrolysis

A novel conversion of sesamolin to sesaminol by acidic cation exchange resin

The relationship of antioxidant components and antioxidant activity of sesame seed oil

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