Antioxidant capacity and HPLC determination of phenolic in different organs of Calligonum polygonoides subspecies comosum

Potent antioxidant and anticancer activities of the methanolic extract of Calligonum comosum (L’Her) fruit hairs against human hepatocarcinoma cells

“…Specifically, desert plants are surrounded by different biotic and abiotic stresses, which forces them to modulate their regulatory metabolic pathways to achieve better adaptation responses against severe climatic and water shortage conditions ( Jahan et al, 2018 ). These highly orchestrated adaptative metabolic strategies lead to the enrichment of plant parts with unique bioactive phytochemicals that belong to several chemical groups including phenolics, flavonoids, alkaloids and terpenoids ( Ahmed et al, 2020 ). Extracts of different plant organs including Calligonum comosum are enriched in their contents of these phytochemicals that exhibit diverse therapeutic properties against various malignant cancer types ( Aboul-Soud et al, 2020 , Ashour et al, 2016 , Aboul-Soud et al, 2016 , Alehaideb et al, 2020 ).…”

“…This potent antioxidant capacity could be explained by the rich contents of phenolic and flavonoid compounds present in fruit hairs. Recently, the in vitro antioxidant potency as well as total flavonoid and total phenolic contents of different C. comosum organs, namely barks, leaves and fruits, have been reported ( Ahmed et al, 2020 , Cheruth et al, 2016 ). Leaves and bark have been shown to exhibit the highest radical scavenging potencies (ascorbic acid equivalent), total phenolic content (gallic acid equivalent), as well as total flavonoid content (rutin equivalent).…”

“…Leaves and bark have been shown to exhibit the highest radical scavenging potencies (ascorbic acid equivalent), total phenolic content (gallic acid equivalent), as well as total flavonoid content (rutin equivalent). Moreover, while flowers and fruits have the highest contents of flavonols, other organs ( i.e ., bark, leaves, and stems), have been found to have the highest concentrations of taxifolin and catechin ( Ahmed et al, 2020 ).…”

“…Arta or Abal is its traditional Arabic name in the Gulf region. The plant has been reported to display several valuable medicinal properties including antioxidant, anti-inflammatory, anti-ulcer, anticancer, antifungal and antihelmentic, estrogenic, hypoglycemic and cardioprotective activities ( Ahmed et al, 2020 ). Its aerial parts ( i.e , leaves, flowers and stems) have traditionally several ethno-medicinal applications including chewing to relief toothache and treat gastric ulcers.…”

“…Different plant parts have been demonstrated to possess potent biological activities ( Ahmed et al, 2020 ). However, the knowledge on the bioactivity of its characteristic fruit hairs is lacking.…”