Antioxidant biomarkers and food intake in elderly women

Boaventura, Brunna Cristina Bremer; Pietro, Patrícia Faria Di; Assis, Maria Alice Altenburg de; Ambrosi, Claudia; Nesello, Luciane Angela Nottar; Silva, F. O. da; Vasconcelos, Francisco de Assis Guedes de; Moreira, José Cláudio Fonseca; Fausto, Maria Arlene

doi:10.1007/s12603-011-0069-6

Cited by 5 publications

(3 citation statements)

References 21 publications

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“…It caused peroxiding balance and experienced antioxidant disorders. The possibility of the release of nitrite oxide (NO) and a decrease in the body's micronutrient levels make the cells more sensitive to oxidative stress and lower SOD level (Afonso et al, 2013;Boaventura et al, 2012) The study showed that there was a correlation between MDA and SOD levels. The higher the MDA level, the lower the SOD level of the Wistar rats, and vice versa.…”

Section: Discussionmentioning

confidence: 99%

Effect of Lissachatina fulica chitosan on the antioxidant and lipid profile of hypercholesterolemic male Wistar rats

Umarudin¹,

Widyarti²,

Warsito³

et al. 2022

J Pharm Pharmacogn Res

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Context: The increase in reactive oxygen species production in hypercholesterolemia can degrade polyunsaturated fatty acids and form malondialdehyde (MDA). There is a need for a natural alternative treatment, such as Lissachatina fulica chitosan. Aims: To analyze the potential of Lissachatina fulica chitosan in increasing the superoxide dismutase (SOD) level, reducing lipid profile, and MDA level of male Wistar rats with hypercholesterolemia model. Methods: The male Wistar rats were divided into six groups (n = 4): P0 (normal control); P1-P5 fed a high-fat diet for four weeks. P1 were treated with fed with a high-fat diet; P2 were treated with ezetimibe of 0.18 mg/200 g BW; P3, P4, and P5 Groups; fed with a high-fat diet and Lissachatina fulica chitosan of 100 mg, 200 mg, and 300 mg/200g BW, respectively. The lipid profile was conducted in rat blood samples by using the CHOP-PAP method, the MDA analysis using the TBARS test, and SOD assay analysis using a kit. Results: The results reveal that the treatment Lissachatina fulica chitosan (300 mg/200 g BW) was significantly effective (p<0.05) to decrease in total cholesterol level (96.7 ± 1.9 mg/dL), triglyceride (75.6 ± 1.6 mg/dL), LDL (29.8 ± 2.5 mg/dL), and MDA (1.2 ± 0.1 nmol/mL) as well as a significant increase (p<0.05) in HDL level (75.0 ± 1.7 mg/dL) and SOD (74.6 ± 2.1 unit/mL). Conclusions: Lissachatina fulica chitosan can reduce total cholesterol, triglyceride, LDL, and MDA, and increase HDL and SOD levels.

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Section: Discussionmentioning

confidence: 99%

Effect of Lissachatina fulica chitosan on the antioxidant and lipid profile of hypercholesterolemic male Wistar rats

Umarudin¹,

Widyarti²,

Warsito³

et al. 2022

J Pharm Pharmacogn Res

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show abstract

“…In addition, the number of different antioxidant foods consumed daily was positively correlated with serum TAS only in women. 19 Thiols are known to be efficient antioxidants due to their ability to react with free radicals, protecting cells against oxidative damage. 18 These findings highlight the relation between the daily consumption of easily accessible fruits and vegetables, whole grains and other common food items and an improvement in the antioxidant status of elderly women.…”

Section: Antioxidants and Agingmentioning

confidence: 99%

Oxidative Stress and Antioxidants in Elderly Women

Boaventura

Pietro

2014

Aging

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“…Thiols, which are present in trace amount in natural samples found their extensive use in cosmetic products, vulcanization processes, preparation of pesticides, drugs for the treatment of hypothyroidism, as biomarkers and as antioxidants in food materials, etc. [11][12][13][14]. Beside these significant roles, biothiols also depict crucial role in many biological processes such that alterations in their level can lead to various diseases like liver damage, oedema, Alzheimer's disease, cardiovascular disease, osteoporosis, cancer and AIDS [15][16][17].…”

Section: Introductionmentioning

confidence: 99%