Antioxidant/Anti-Inflammatory Activities and Chemical Composition of Extracts from the Mushroom Trametes Versicolor

Abstract

Abstract:The mushroom, Trametes versicolor is commonly used as a traditional Chinese medicine and is known to exhibit various biological activities. However, its antioxidant activity has remained unknown. In the present study, various extracts obtained from the Trametes versicolor mushroom were examined for antioxidant and anti-inflammatory activities. Among the extracts obtained with Soxhlet extraction, the extract from acetone exhibited the highest antioxidant activity (50.9%), followed by the extracts from methanol (33.9%), n-hexane (29.5%), and chloroform (15.2%) at the level of 500 µg/mL. This acetone fraction displayed a dose-dependent anti-inflammatory activity or lipoxygenase inhibitory activity by 76.4% at 500 µg/mL, 55.6% at 200 µg/mL, and 37.0% at 100 µg/mL. Among a total of 76 compounds identified in this acetone extract, hexadecanoic acid was the largest component (18.11 mg/kg), followed by 5-hydroxy-2-pentanone (17.33 mg/kg), lactic acid (3.25 mg/kg), and acetic acid (3.21 mg/kg). The following possible principles of antioxidant activity were identified: furfural (1.48 mg/kg), γ-butyrolactone (0.51 mg/kg), furfuryl alcohol (0.49 mg/kg), 2-methoxy-4-vinylphenol (0.49 mg/kg), and 2,6-dimetoxy-4-vinylphenol (0.33 mg/kg), and benzaldehyde (0.15 mg/kg).

Role of Degradation Products of Chlorogenic Acid in the Antioxidant Activity of Roasted Coffee

“…18 The DPPH assay was conducted according to a previously reported method. 19 Briefly, a mixture containing a test sample (500 μL/mL) and 300 mM DPPH (500 μL) was incubated at room temperature for 30 min, and then the absorbance at 517 nm was measured using a Hewlett-Packard 8452A diode array spectrophotometer (Hewlett-Packard Co., Palo Alto, CA, USA). Butylated hydroxytoluene Journal of Agricultural and Food Chemistry (BHT; 100 μg/mL) was used as a standard antioxidant to validate the assay.…”

Antioxidative, antifungal, cytotoxic and antineurodegenerative activity of selected Trametes species from Serbia

“…Kamiyama et al [41] reported that, depending on solvent, extract of T . versicolor fruiting bodies can neutralise up to 50% DPPH•, and Johnsy and Kaviyarasana [40] that methanolic extract of T .…”

Bimetallic Pd-Au/SiO2 Catalysts for Reduction of Furfural in Water

“…The possibility of using THFA as a fuel results from its relatively high octane number (ON = 83) as well as its physical and chemical similarity to kerosene. Moreover, the products of THFA etherification can be used as diesel fuel additives, reducing emissions of solid particles [3,19,28,[31][32][33][34].Another interesting product of furfural reduction is a pair of tautomers: 5-hydroxy-2-pentanone and 2-methyloxolan-2-ol. These compounds occur naturally in the environment, for example in the Trametes versicolor mushrooms, and probably have antioxidant/anti-inflammatory activities [33].…”

“…The possibility of using THFA as a fuel results from its relatively high octane number (ON = 83) as well as its physical and chemical similarity to kerosene. Moreover, the products of THFA etherification can be used as diesel fuel additives, reducing emissions of solid particles [3,19,28,[31][32][33][34].…”

“…Another interesting product of furfural reduction is a pair of tautomers: 5-hydroxy-2-pentanone and 2-methyloxolan-2-ol. These compounds occur naturally in the environment, for example in the Trametes versicolor mushrooms, and probably have antioxidant/anti-inflammatory activities [33]. These expensive intermediates are used in the synthesis of amino acids, fragrances, pharmaceuticals, Catalysts 2020, 10, 444 3 of 23…”