Antioxidant and α-glucosidase inhibitory activities of eight neglected fruit extracts and UHPLC-MS/MS profile of the active extracts

Yunus, Siti Norhamimah Mohamed; Abas, Faridah; Jaafar, Ahmad Haniff; Azizan, Awanis; Zolkeflee, Nur Khaleeda Zulaikha; Ghafar, Siti Zulaikha Abd

doi:10.1007/s10068-020-00856-x

Cited by 8 publications

(2 citation statements)

References 32 publications

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“…The inhibition of these enzymes is one of the mechanisms that reduces postprandial hyperglycemia in diabetic patients [ 50 ]. Ethanolic extracts from S. dulcis leaves [ 51 ] and fruit [ 52 ] presented anti-α-glucosidase activity with IC 50 of 45.52 µg/mL and 4.73 µg/mL, respectively.…”

Section: Pharmacological Activitymentioning

confidence: 99%

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Spondias sp: Shedding Light on Its Vast Pharmaceutical Potential

et al. 2023

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Many plants are used by the population through popular knowledge passed from generation to generation for the treatment of various diseases. However, there is not always any scientific content supporting these uses, which is very important for safety. One of these plants is the fruit of the Spondias genus, which during its processing generates various residues that are discarded, but which also have pharmacological properties. The focus of this review is to survey the pharmacological activities that Spondias genus shows, as well as which part of the plant is used, since there is a lot of richness in its by-products, such as leaf, bark, resin, seed, and peel, which are discarded and could be reused. The main activities of this genus are antioxidant, anti-inflammatory, antidiabetic, antifungal, and antiviral, among others. These properties indicate that this genus could be used in the treatment of several diseases, but there are still not many products available on the market that use this genus as an active ingredient.

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Section: Pharmacological Activitymentioning

confidence: 99%

“…Ethanolic extracts of S. dulcis leaves and fruits presented IC 50 for DPPH scavenging assay of 14.22 µg/mL and 27.14 µg/mL, respectively [ 51 , 52 ]. Moreover, methanolic extracts were more effective antioxidants, with an IC 50 of 5.37 ug/mL for the leaves and IC 50 of 1.91 µg/mL for the fruit [ 49 ].…”

Section: Pharmacological Activitymentioning

confidence: 99%