Antioxidant and emulsifying activity of N-(long-chain-acyl)histidine and N-(long-chain-acyl)carnosine

Abstract

The antioxidant activity of N-(long-chain-acyl)histidine-containing compounds was investigated. In a homogeneous solution of methyl linoleate with a radical initiator, these compounds suppressed the production of methyl linoleate hydroperoxides. When the oxidation of phosphatidylcoline liposomes was induced by ferrous ion and ascorbic acid, N-(long-chain-acyl)histidine and TV-(long-chain-acyl)camosine could suppress the oxidation more efficiently than histidine and carnosine. The emulsifying activities of these compounds were found to be higher than those of conventional surfactants, that is, casein, Tween 80, and Triton X-100.

Purification and characterization of antioxidative peptides from protein hydrolysate of lecithin‐free egg yolk

“…The antioxidative activity of histidine-containing peptides has been reported (25,26). This activity may be attributed to the chelating and lipid radical-trapping ability of the imidazole ring.…”

Amino acid composition, molecular weight distribution and antioxidant activity of protein hydrolysates of soy sauce lees

“…It could be one of the mechanisms leading to the increase of DPPH radical scavenging activity. The antioxidant amino acids contributed much to the antioxidant activity of protein hydrolysates (Murase, Nagao, & Terao, 1993;Rajapakse, Mendis, Jung, Je, & Kim, 2005). The proportion of antioxidant amino acids to total amino acids was in a decreasing order, S1 > S2 > S3 > S4 = S5 = S6.…”

Characterization of an antioxidant peptide from katsuobushi (dried bonito) protein hydrolysates

“…Furthermore, it has been shown that hydrophobic amino acids in addition to one or more residues of histidine, proline, methionine, cysteine, tyrosine, tryptophan, and phenylalanine can enhance the activities of antioxidant peptides. [32,33]. Moreover, evidence suggests that functional peptides are dependent on amino acid sequence and structure [33].…”

“…[32,33]. Moreover, evidence suggests that functional peptides are dependent on amino acid sequence and structure [33]. Li et al reported that the antioxidant activity of histidine-containing peptides was attributed to the proton-donating ability of the histidine imidazole group [28].…”