Antioxidant and antimicrobial properties of some Chinese plant extracts

Duffy, Colm; Power, Ronan F.

doi:10.1016/s0924-8579(01)00326-0

Cited by 140 publications

(97 citation statements)

References 11 publications

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“…Moreover, Gram-negative bacteria have efflux pumps that reduce the cellular levels of antibiotics. 39 Among the isolated compounds, only quercetin obtained from the AcOEt fraction showed good activity for all bacteria tested. Thus, quercetin may be responsible for the observed activity of the AcOEt fraction, especially against Gram-negative bacteria.…”

Section: Resultsmentioning

confidence: 95%

Bioactive triterpenes and phenolics of leaves of Eugenia brasiliensis

Magina¹,

Dalmarco²,

Dalmarco³

et al. 2012

Quím. Nova

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Recebido em 10/10/11; aceito em 17/1/12; publicado na web em 15/5/12 A chemical investigation of Eugenia brasiliensis Lam. (Myrtaceae) leaves led to the isolation of a-amyrin and b-amyrin (in a mixture), betulin, 29-hydroxy-oleanolic acid, quercetin, catechin and gallocatechin. Herein, the identification of 29-hydroxy-oleanolic acid is reported for the first time in the Myrtaceae family. Moreover, in this study, the extract, fractions and six of the seven compounds were monitored for toxicity toward Artemia salina, antibacterial and acetylcholinesterase inhibitory activity. The crude ethanol extract of the leaves and fractions were found be active on A. salina toxicity bioassay.

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Section: Resultsmentioning

confidence: 95%

Bioactive triterpenes and phenolics of leaves of Eugenia brasiliensis

Magina¹,

Dalmarco²,

Dalmarco³

et al. 2012

Quím. Nova

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“…This can be explained because the outer membrane of Gramnegative bacteria is known to present a barrier to the penetration of numerous antibiotic molecules, and the periplasmic space contains enzymes which are able of breaking down foreign molecules introduced from outside (Schaechter et al, 1999;Duffy and Power, 2001;Sartori et al, 2003). Many Gram-negative organisms also exhibit intrinsic high-level resistance to a range of antimicrobial agents and support a role for the outer membrane and active efflux as a barrier to antibiotics (Nikaido, 1989;Köhler, 1999;Van Bambeke et al, 2003).…”

Section: Resultsmentioning

confidence: 99%

Antimicrobial Activity of Fractions and Compounds from Calophyllum brasiliense (Clusiaceae/Guttiferae)

Pretto

Cechinel‐Filho

Noldin

et al. 2004

Zeitschrift Für Naturforschung C

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Calophyllum brasiliense (Clusiaceae/Guttiferae) is a native Brazilian medicinal plant traditionally used against several diseases, including infectious pathologies. Crude methanolic extracts (CME) and two fractions, denoted non-polar (soluble in chloroform) and polar (nonsoluble in chloroform), were prepared from different parts of the plant (roots, stems, leaves, flowers and fruits) and studied. The following compounds were isolated and tested against pathogenic bacteria and yeasts by determination of the minimal inhibitory concentration (MIC): brasiliensic acid (1), gallic acid (2), epicatechin (3), protocatechuic acid (4), friedelin (5) and 1,5-dihydroxyxanthone (6). The results indicated that all the parts of the plant exhibited antimicrobial activity against Gram-positive bacteria, which are selectively inhibited by components of C. brasiliense. No activity was observed against Gram-negative bacteria and yeasts tested. Regarding the isolated compounds, substance 4 showed antimicrobial activity against all the tested microorganisms, whereas compound 6 exhibited antimicrobial activity only against Gram-positive bacteria. The results from the current study confirm and justify the popular use of this plant to treat infectious processes.

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“…The antibacterial activity of the medicinal plant extracts depends on the presence of different concentrations of secondary metabolites such as tannin, saponin, and glycosides [23] [24] [25]. Herein, the highest amount (+++) of tannin was present in the ethanolic stem extract followed by the aqueous stem extract (++) ( Table 1 outer membrane and a unique periplasmic space which is not found in grampositive bacteria and, therefore, they showed different antimicrobial activity against the tested sample extracts [28]. Stem extracts have higher antimicrobial activity than that of the leaf extracts.…”

Section: Antimicrobial Activitymentioning

confidence: 99%

Investigation of the Phytochemicals, Antioxidant, and Antimicrobial Activity of the <i>Andrographis paniculata</i> Leaf and Stem Extracts

Polash¹,

Saha²,

Hossain³

et al. 2017

ABB

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Andrographis paniculata (Kalmegh) has been considered as a medicinal shrub and used as a medicinal plant in the remote areas of Bangladesh. A. paniculata leaf and stem extracts were prepared using the polar (i.e., water, and 70% ethanol) and nonpolar (i.e., hexane) solvents. The phytochemical contents, total phenol contents (TPC), antioxidant activity, and antibacterial activity of all the extracts of A. paniculata leaf and stem were investigated. Both the gram-positive (i.e., Bacillus subtillis) and gram-negative (i.e., E. coli, and Salmonella typhi) strains of bacteria were used for the antibacterial activity assay of the sample extracts. The ethanolic stem extracts contained the maximum amount of TPC when compared to that of the leaf extracts. However, the aqueous stem extracts had the highest free radical scavenging activity in vitro. The extracts prepared from A. paniculata stem showed better antibacterial activity against all the strains of bacteria (i.e., E. coli, S. typhi, and B. subtillis) when compared to that of the leaf extracts. More specifically, the aqueous stem extract showed superior antibacterial effect against E. coli, and B. subtillis, and the zones of inhibition were 21 mm, and 29 mm in diameter, respectively. On the other hand, the ethanolic stem extract showed the maximum antibacterial activity against S. typhi and the zone of inhibition was 8.15 mm.The minimum inhibitory concentration (MIC) value and IC 50 value for all the A. paniculata extracts were ~0.05 μg/μL, and ~1 μg/μL, respectively.

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Antioxidant and antimicrobial properties of some Chinese plant extracts

Cited by 140 publications

References 11 publications

Bioactive triterpenes and phenolics of leaves of Eugenia brasiliensis

Bioactive triterpenes and phenolics of leaves of Eugenia brasiliensis

Antimicrobial Activity of Fractions and Compounds from Calophyllum brasiliense (Clusiaceae/Guttiferae)

Investigation of the Phytochemicals, Antioxidant, and Antimicrobial Activity of the <i>Andrographis paniculata</i> Leaf and Stem Extracts

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Antioxidant and antimicrobial properties of some Chinese plant extracts

Cited by 140 publications

References 11 publications

Bioactive triterpenes and phenolics of leaves of Eugenia brasiliensis

Bioactive triterpenes and phenolics of leaves of Eugenia brasiliensis

Antimicrobial Activity of Fractions and Compounds from Calophyllum brasiliense (Clusiaceae/Guttiferae)

Investigation of the Phytochemicals, Antioxidant, and Antimicrobial Activity of the &lt;i&gt;Andrographis paniculata&lt;/i&gt; Leaf and Stem Extracts

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Investigation of the Phytochemicals, Antioxidant, and Antimicrobial Activity of the <i>Andrographis paniculata</i> Leaf and Stem Extracts