Antioxidant and antimicrobial efficacy of a biflavonoid, amentoflavone from Nandina domestica in vitro and in minced chicken meat and apple juice food models

Bajpai, Vivek K.; Park, InWha; Lee, JungIn; Shukla̽, Shruti; Nile, Shivraj Hariram; Chun, Hyang Sook; Khan, Imran; Oh, Sejong; Lee, Hoomin; Huh, Yun Suk; Na, MinKyun; Han, Young‐Kyu

doi:10.1016/j.foodchem.2018.07.159

Cited by 50 publications

(36 citation statements)

References 28 publications

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“…As aforementioned, herbal extracts and EOs from plants can be considered as potential alternatives to artificial preservatives to improve the shelf life and the safety of food products such as meat and poultry and RTE meat products (49). EOs, which also known as volatile or ethereal oils, are naturally aromatic components found in many plants.…”

Section: Eos Composition and Mechanisms Of Their Antimicrobial Activitymentioning

confidence: 99%

“…EOs, which also known as volatile or ethereal oils, are naturally aromatic components found in many plants. They can be obtained from various parts of plants including buds, flowers, seeds, leaves, roots, peels, fruits, barks, and woods through only physical extraction and isolation such as pressing and distillation (3,49).…”

Section: Eos Composition and Mechanisms Of Their Antimicrobial Activitymentioning

confidence: 99%

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Potential Application of Essential Oils for Mitigation of Listeria monocytogenes in Meat and Poultry Products

2020

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One of the most important challenges in the food industry is to provide healthy and safe food. Therefore, it is not possible to achieve this without different processes and the use of various additives. In order to improve safety and extend the shelf life of food products, various synthetic preservatives have been widely utilized by the food industry to prevent growth of spoilage and pathogenic microorganisms. On the other hand, consumers' preference to consume food products with natural additives induced food industries to use natural-based preservatives in their production. It has been observed that herbal extracts and their essential oils could be potentially considered as a replacement for chemical antimicrobials. Antimicrobial properties of plant essential oils are derived from some main bioactive components such as phenolic acids, terpenes, aldehydes, and flavonoids that are present in essential oils. Various mechanisms such as changing the fatty acid profile and structure of cell membranes and increasing the cell permeability as well as affecting membrane proteins and inhibition of functional properties of the cell wall are effective in antimicrobial activity of essential oils. Therefore, our objective is to revise the effect of various essential oils and their bioactive components against Listeria monocytogenes in meat and poultry products.

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Section: Eos Composition and Mechanisms Of Their Antimicrobial Activitymentioning

confidence: 99%

Section: Eos Composition and Mechanisms Of Their Antimicrobial Activitymentioning

confidence: 99%

Potential Application of Essential Oils for Mitigation of Listeria monocytogenes in Meat and Poultry Products

2020

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“…Amentoflavone is a biflavonoid present in leaves of Ginkgo biloba L., Garcinia brasiliensis L., and Nandina domestica L. [66][67][68]. This biflavonoid has a high antioxidant capacity (19.21-75.52%), demonstrated in scavenging tests of DPPH, ABTS, superoxide, and hydroxyl radicals [67].…”

Section: Occurrence and Antioxidant Properties Of Anticoronavirus Commentioning

confidence: 99%

“…Amentoflavone is a biflavonoid present in leaves of Ginkgo biloba L., Garcinia brasiliensis L., and Nandina domestica L. [ 66 – 68 ]. This biflavonoid has a high antioxidant capacity (19.21–75.52%), demonstrated in scavenging tests of DPPH, ABTS, superoxide, and hydroxyl radicals [ 67 ]. Moreover, amentoflavone prevents acute lung injury induced by sepsis in rats by decreasing thiobarbituric acid reactive substance (TBARS) levels and by increasing levels of SOD and GSH [ 69 ].…”

Section: Occurrence and Antioxidant Properties Of Anticoronavirus mentioning

confidence: 99%

Natural Antioxidants: A Review of Studies on Human and Animal Coronavirus

Diniz¹,

Filho

Fielding

et al. 2020

Oxidative Medicine and Cellular Longevity

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The outbreaks of viruses with wide spread and mortality in the world population have motivated the research for new therapeutic approaches. There are several viruses that cause a biochemical imbalance in the infected cell resulting in oxidative stress. These effects may be associated with the development of pathologies and worsening of symptoms. Therefore, this review is aimed at discussing natural compounds with both antioxidant and antiviral activities, specifically against coronavirus infection, in an attempt to contribute to global researches for discovering effective therapeutic agents in the treatment of coronavirus infection and its severe clinical complications. The contribution of the possible action of these compounds on metabolic modulation associated with antiviral properties, in addition to other mechanisms of action, is presented.

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“…The DPPH and ABTS radical scavenging activity of AMF at three concentrations (10, 50 and 100 µM) in the absence or presence of the UDPGA system were evaluated using a previously method. [26,27] Quercetin treatment was used as the positive group. The percentage of inhibitory effect was calculated using the following formula: radical scavenging activity (% inhibition) = (Abs control − Abs sample )/Abs control 9 100.…”

Section: Scavenging Of Dpph and Abtsmentioning

confidence: 99%

Glucuronidation and its effect on the bioactivity of amentoflavone, a biflavonoid from Ginkgo biloba leaves

Gan

You

et al. 2020

Journal of Pharmacy and Pharmacology

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Objectives Ginkgo biloba leaves contain amentoflavone (AMF), a dietary flavonoid that possesses antioxidant and anticancer activity. Flavonoids are extensively subjected to glucuronidation. This study aimed to determine the metabolic profile of AMF and the effect of glucuronidation on AMF bioactivity. Methods A pharmacokinetic study was conducted to determine the plasma concentrations of AMF and its metabolites. The metabolic profile of AMF was elucidated using different species of microsomes. The antioxidant activity of AMF metabolites was determined using DPPH/ABTS radical and nitric oxide assays. The anticancer activity of AMF metabolites was evaluated in U87MG/U251 cells. Key findings Pharmacokinetic studies indicated that the oral bioavailability of AMF was 0.06 ± 0.04%, and the area under the curve of the glucuronidated AMF metabolites (410.938 ± 62.219 ng/ml h) was significantly higher than that of AMF (194.509 ± 16.915 ng/ml h). UGT1A1 and UGT1A3 greatly metabolized AMF. No significant difference was observed in the antioxidant activity between AMF and its metabolites. The anticancer activity of AMF metabolites significantly decreased. Conclusions A low AMF bioavailability was due to extensive glucuronidation, which was mediated by UGT1A1 and UGT1A3. Glucuronidated AMF metabolites had the same antioxidant but had a lower anticancer activity than that of AMF.

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Antioxidant and antimicrobial efficacy of a biflavonoid, amentoflavone from Nandina domestica in vitro and in minced chicken meat and apple juice food models

Cited by 50 publications

References 28 publications

Potential Application of Essential Oils for Mitigation of Listeria monocytogenes in Meat and Poultry Products

Potential Application of Essential Oils for Mitigation of Listeria monocytogenes in Meat and Poultry Products

Natural Antioxidants: A Review of Studies on Human and Animal Coronavirus

Glucuronidation and its effect on the bioactivity of amentoflavone, a biflavonoid from Ginkgo biloba leaves

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