Antioxidant and antimicrobial activities of green tea extract loaded into nanostructured lipid carriers

Manea, Adrian; Vasile, Bogdan Ștefan; Meghea, Aurelia

doi:10.1016/j.crci.2013.07.015

Cited by 90 publications

(39 citation statements)

References 31 publications

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“…The antioxidant activity of NLCs-green tea extract was enhanced in comparison with that of pure green tea extract. NLC produced by Tween20 had less Z-avg than Tween80 [ 105 ].…”

Section: Nanoparticlesmentioning

confidence: 97%

Nano-encapsulation of a Natural Polyphenol, Green Tea Catechins: Way to Preserve Its Antioxidative Potential

Dang

Gupta

Bansal

et al. 2014

Free Radicals in Human Health and Disease

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Emanating from extensive research carried out all over the globe, green tea has been acknowledged for plethora of pharmacological activities like anti-infl ammatory, antimicrobial, antitumor, antiaging, and many more. This wide array of health effects have been attributed to green tea catechins (GTCs). These GTCs correspond to the class of antioxidants which scavenge the precarious free radicals in the body and, thus, prevent the progression of various diseases. However, poor bioavailability, short halflife, stability issues, and short shelf life hamper its use as a therapeutic agent. To address these limitations, various encapsulation techniques have been explored by the scientists. The encapsulation techniques employed for green tea and its catechins range from microparticles, microcapsules, nanoparticles, and lipid nanocapsules to self assembly approaches like liposomes, micelles, and microemulsions. Encapsulation not only helps in enhancing the aqueous solubility and stability of the GTCs but also provides for controlled and sustained release thus protecting their biological/ pharmacological activity in systemic circulation. At the same time, sustained release is likely to enhance bioavailability and thus can reduce the likelihood of repeated use. The aim of this chapter is to discuss the role of green tea as an antioxidant and various nano-encapsulation strategies to enhance the effi cacy of related products. It also provides an insight into some of the commercial and patented green tea-based products.

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“…The antioxidant activity of NLCs-green tea extract was enhanced in comparison with that of pure green tea extract. NLC produced by Tween20 had less Z-avg than Tween80 [ 105 ].…”

Section: Nanoparticlesmentioning

confidence: 97%

Nano-encapsulation of a Natural Polyphenol, Green Tea Catechins: Way to Preserve Its Antioxidative Potential

Dang

Gupta

Bansal

et al. 2014

Free Radicals in Human Health and Disease

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“…Ginkgolides A, B, C and bilobalide from a marketed extract had association efficiency around 80%. In this way, a controlled release of the four components was observed both in vivo and in vitro, showing a cumulative release of 60% after 24 h. Concerning commercial green tea extract, both hypocholesterolemic and antibactericidal (Manea et al, 2014) were tested using nanoemulsion and nanostructured lipid carriers, respectively . For its hypercholesteremic activity, only LDL receptor expression was higher for the nanosystems in comparison to free extract.…”

Section: Other Extractsmentioning

confidence: 99%

On the use of nanotechnology-based strategies for association of complex matrices from plant extracts

Zorzi

Carvalho

Poser

et al. 2015

Revista Brasileira de Farmacognosia

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Please cite this article in press as: Zorzi, G., et al. On the use of nanotechnology-based strategies for association of complexes matrices from plant extracts. Revista Brasileira de Farmacognosia (2015), http://dx.BJP 159 1-11 Revista Brasileira de Farmacognosia xxx (2015) xxx-xxx w w w . s b f g n o s i a . o r g . b r / r e v i s t a a b s t r a c tDepending on the method of extraction, plant extracts can contain an enormous variety of active molecules, such as phenolic compounds, essential oils, alkaloids, among others. In many cases, from a pharmacological point of view, it is interesting to work with crude extract or fractions instead of a single isolated compound. This could be due to multi-targeting effect of the extract, lack of knowledge of the active compounds, synergistic effect of the extract compounds, among others. In any case, in order to achieve a final product some issues must be overcome, including poor stability, solvent toxicity, and low solubility of the bioactive compound. Recently many nanotechnology-based strategies have been proposed as an alternative to solve these problems, especially liposomes, nanoemulsions and nanoparticles. In this sense, the present work aims to review the main nanotechnological approaches used for association of different plant extracts and the main achievements form using these technologies.

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“…Among antifungal drugs, the most important classes of antifungal compounds are polyenes, azole and echinocandins derivatives [13]. Many natural products, such as green tea [14], thyme [15,16], basil oil or other herbs proved to be effective in the treatment of topical fungal infections [17,18].…”

Section: Introductionmentioning

confidence: 99%

Influence of basil oil extract on the antioxidant and antifungal activities of nanostructured carriers loaded with nystatin

Badea

Bors

Lăcătuşu

et al. 2015

Comptes Rendus Chimie

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Antioxidant and antimicrobial activities of green tea extract loaded into nanostructured lipid carriers

Cited by 90 publications

References 31 publications

Nano-encapsulation of a Natural Polyphenol, Green Tea Catechins: Way to Preserve Its Antioxidative Potential

Nano-encapsulation of a Natural Polyphenol, Green Tea Catechins: Way to Preserve Its Antioxidative Potential

On the use of nanotechnology-based strategies for association of complex matrices from plant extracts

Influence of basil oil extract on the antioxidant and antifungal activities of nanostructured carriers loaded with nystatin

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