Antioxidant and antimicrobial activities of Smilax china L. leaf extracts

Seo, Hye-Kyung; Lee, Jong-Hwa; Kim, Hyun-Su; Lee, Chang-Kwon; Lee, Seung‐Cheol

doi:10.1007/s10068-012-0229-4

Cited by 24 publications

(24 citation statements)

References 20 publications

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“…Of particular interest is the good inhibitory activity of Smilax spp, against methicillin-resistant strains of S. aureus, suggesting that this organic extract probably contains novel antibacterial compounds useful for the treatment of resistant staphylococcal infections. This suggestion could be reinforced with previous reports that describe the potent antibacterial activity of two taxonomically related species, S. china and S. glabra (Seo et al, 2012;Xu et al, 2013). One of the aforementioned studies reported two epicatechins (smiglabrone A and cinchonain Ib), two stilbenes (smiglastilbene and trans-resveratrol) and two flavanones (smilachromanone and sakuranetin) as the most bioactive molecules against S. aureus, methicillin-resistant S. aureus, and E. faecalis, all having MICs in the range of 0.08-1.05 mM (Xu et al, 2013).…”

Section: Antibacterial Activitysupporting

confidence: 81%

Screening for antibacterial and antiprotozoal activities of crude extracts derived from Mexican medicinal plants

Garcia¹,

Mata-Cardenas²,

Garza-Gonzalez³

et al. 2015

Afr. J. Trad. Compl. Alt. Med.

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Background: Crataegus mexicana, Hyptis albida, Larrea tridentata, Ocimum baislicum, Prunus serotina, and Smilax spp. are used in Mexican traditional medicine to treat respiratory and gastrointestinal diseases such as flu, cough, diarrhea, dysentery, and other parasitic or microbial infections. Therefore this study was aimed at the pharmacological prospection of these plants against eleven bacterial species and three amitochondrial protist pathogens. Material and methods:The fruits or aerial parts of C. mexicana, H. albida, L. tridentata, O. baislicum, P. serotina, and Smilax spp. were extracted with different solvents. The antibacterial properties of organic and aqueous extracts of these plants were determined by the microdilution method and the microplate alamar blue assay against Stenotrophomonas maltophilia, Escherichia coli, Acinetobacter baumannii, Pseudomonas aeruginosa, Klebsiella pneumoniae, Enterobacter cloacae, Staphylococcus aureus, methicillin-resistant S. aureus, Listeria monocytogenes, Enterococcus faecalis, and Mycobacterium tuberculosis, whereas anti-protozoal activities of extracts were evaluated by a vial micro-assay against strains of Entamoeba histolytica, Trichomonas vaginalis, and Giardia lamblia. Results: H. albida, Smilax spp, and C. mexicana showed good activity against the Gram-positive strains, S. aureus, methicillin-resistant S. aureus, and E. faecalis. Four extracts (C. mexicana, H. albida, O. basilicum, and L. tridentata) showed good activity against E. histolytica, T. vaginalis, and G. lamblia. Conclusion:The extracts of these six medicinal plants could be a source for new antibacterial and antiprotozoal drugs. For this reason they are currently under investigation to isolate and characterize their active compounds.

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Section: Antibacterial Activitysupporting

confidence: 81%

Screening for antibacterial and antiprotozoal activities of crude extracts derived from Mexican medicinal plants

Garcia¹,

Mata-Cardenas²,

Garza-Gonzalez³

et al. 2015

Afr. J. Trad. Compl. Alt. Med.

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“…However, until recently, there have been few studies about the pharmacological effects of the leaves of Smilax excelsa. In vitro antioxidant properties of leaf extracts were shown in one study on Smilax china [37] after our research [23] . Nephroptotective activity of extracts obtained from S. china rhizomes in hyperuricemic animals was demonstrated in a recent study without histopathological observation [38] .…”

Section: Discussionmentioning

confidence: 80%

Deneysel Olarak Oluşturulmuş Böbrek Hasarı Üzerine Smilax excelsa L. Kullanımının Değerlendirilmesi

Özsoy¹,

Okyar²,

Arda-Pirincci³

et al. 2013

Kafkas Univ Vet Fak Derg

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SummaryThe protective effect of an aqueous extract of the shoots and leaves of Smilax excelsa L. against acute carbon tetrachloride (CCl 4 )-induced toxicity and the changes in antioxidative defense activities in kidney of rats were investigated. Female Wistar rats were supplied with S. excelsa shoots and leaves aqueous extract once a day for 9 days (orally at a dose of 100, 200 and 400 mg/kg of body weight) prior to renal injury induction through intraperitoneal injection with a single dose of CCl 4 (1 ml/kg body wt, in a 20 % v/v olive oil solution) on the 10th day. 24 h after CCl 4 intoxication serum and tissue biochemical and hispathological analyses were undertaken after sacrification under anesthesia. Administration of the extract reversed the antioxidant parameters which were impaired in CCl 4 group, in a dose dependent manner and at a dose of 400 mg/kg of body weight the levels of almost all the parameters were almost back to normal Control group. Nevertheless, the extract did not completely improve the CCl 4 -induced degenerative changes observed microscopically in kidney tissue. The results of this study suggest that S. excelsa could protect the kidney tissue against CCl 4 -induced nephrotoxicity in rats, probably by increasing antioxidative defense activities. Keywords: Smilax excelsa, Renal damage, Carbon tetrachloride, Antioxidant effect, Nephrotoxicity Deneysel Olarak Oluşturulmuş Böbrek Hasarı ÜzerineSmilax excelsa L. Kullanımının Değerlendirilmesi ÖzetBu çalışmada Smilax excelsa L. 'nın genç sürgün ve yapraklarının sulu ekstresinin sıçanlarda karbon tetraklorür (CCl 4 ) ile deneysel olarak oluşturulmuş böbrek hasarına olan etkisi ve antioksidan savunma sistemindeki değişiklikleri incelendi. Wistar albino dişi sıçanlara, 9 gün süre ile, S. excelsa extresinin 100, 200 ve 400 mg/kg dozunda oral olarak uygulanmasının ardından, 10. gününde CCl 4 'ün %20'lik zeytin yağındaki solüsyonunun 1ml/kg intraperitoneal verilmesiyle böbrek harabiyeti oluşturuldu. CCl 4 uygulanmasından 24 saat sonra, sıçanlar anestezi altında öldürüldü, ardından serum ve böbrek dokusunda biyokimyasal ve histopatolojik analizler yapıldı. CCl 4 grubunda bozulan tüm değerlerin, ekstrenin verilmesiyle doza bağlı olarak düzeldiği ve 400 mg/kg dozunda aşağı yukarı normal Kontrol grubu değerlerine ulaştığı gözlemlendi. Buna karşın, ekstre CCl 4 ile oluşturulan, böbrek dokusunda mikroskobik olarak gözlenen dejeneratif değişiklikleri tam olarak iyileştirmedi. Bu çalışmanın sonucunda, S. excelsa'nın sıçanlarda böbrek dokusunu CCl 4 ile oluşturulan hasardan koruduğu ve bu etkisini organizmanın antioksidan savunma sistemlerini arttırarak gösterdiği ileri sürülebilir.

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“…The TPC of the extracts was determined following the method of Seo et al, (2012). 1 mL of the diluted extract was mixed with 1 mL of 2% Na2 CO3 and 1 mL of 50% Folin-Ciocalteu reagent, and centrifuged at 13,400×g for 5 min.…”

Section: Total Phenolic Contents (Tpc)mentioning

confidence: 99%

“…The DPPH radical scavenging activity of the extracts was determined according to the method of Seo et al, (2012). The extracts diluted with DMSO, and then 0.1 mL of each extract was mixed with 0.9 mL of 0.041 mM DPPH in ethanol for 30 min.…”

Section: Dpph Radical Scavenging Activitymentioning

confidence: 99%

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Pourashouri¹,

Shábanpour²,

Abad³

et al. 2016

Turk. J. Fish. Aquat. Sci.

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The objective of this study was to investigate the effectiveness of plant extracts on the oxidative stability of n-3 rich fish oil emulsion. The antioxidant efficiency, water extracts of wild pistachio, rosemary and green tea, were evaluated in 10 % fish oil-in-water emulsions. The fish oil emulsion was oxidatively unstable as measured by fatty acid profile, peroxide and pAnisidine values and sensory analysis. Pre-emulsification of the fish oil with fish gelatin in water offered some protection towards oxidation, but addition of the extracts (200, 500 and 700 ppm) significantly reduced oxidative changes. Higher concentration of the extracts showed an antioxidant tendency in 10% fish oil-in-water emulsion. Moreover, the results of the experiment demonstrated the potential of wild pistachio leaf extract as a useful antioxidant.

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Antioxidant and antimicrobial activities of Smilax china L. leaf extracts

Cited by 24 publications

References 20 publications

Screening for antibacterial and antiprotozoal activities of crude extracts derived from Mexican medicinal plants

Screening for antibacterial and antiprotozoal activities of crude extracts derived from Mexican medicinal plants

Deneysel Olarak Oluşturulmuş Böbrek Hasarı Üzerine Smilax excelsa L. Kullanımının Değerlendirilmesi

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