Antioxidant and antihemolytic activity of lipid-soluble bioactive substances in avocado fruits

Abstract

Antioxidant and antihemolytic activity of lipid-soluble bioactive substances in avocado fruits. Abstract-Introduction. Persea americana (avocado) fruit is known to be a rich source of proteins and minerals, as well as vitamins. Although many biological activities have been reported for avocado fruit, far less attention has been paid to the biological properties of its lipid-soluble bioactive substances. The aim of this study was to evaluate the antioxidant and antihemolytic activity of lipid-soluble bioactive compounds of avocado fruit. Materials and methods. Antioxidant and antihemolytic activity of lipid-soluble bioactive compounds of avocado fruit was assessed by employing different methods. Also, the ability of avocado fruit to protect fluorescein against oxidant-induced bleaching was evaluated. Results and discussion. The tested sample showed good antioxidant and antihemolytic activities. There was no significant difference between the reducing power of lipid-soluble bioactive substances in avocado fruits and ascorbic acid (p < 0.05). The tested sample showed weak ferrous ion-chelating activity. The sample exhibited moderate hydrogen peroxide scavenging activity, but exhibited good antioxidant activity. Avocado fruit showed very good activity against 2,2′-azobis(2-amidinopropane) dihydrochloride-and hydrogen peroxide-induced hemolysis in erythrocytes. Furthermore, it showed good protective effects against peroxyl radical-induced bleaching in fluorescein. Conclusion. Lipid-soluble bioactive substances of avocado fruit showed good activity in all of the studied models. Iran Islamic Republic / Persea americana / fruits / lipid peroxidation / nitric oxide / antioxidants / antihemolysis Activités antioxydante et antihémolytique de substances bioactives liposolubles dans l'avocat. Résumé-Introduction. Les fruits de Persea americana, ou avocats, sont connus pour être riches en protéines et minéraux, ainsi qu'en vitamines. Bien que de nombreuses activités biologiques aient été signalées pour ce fruit, beaucoup moins d'attentions n'ont été accordées aux propriétés biologiques de ses substances bioactives liposolubles. L'objectif de notre étude a été d'évaluer l'activité antioxydante et antihémolytique de composés bioactifs liposolubles du fruit de l'avocat. Matériel et méthodes. L'activité antioxydante et antihémolytique des composés bioactifs liposolubles de l'avocat a été évaluée par différents moyens. En outre, la capacité des avocats à protéger la fluorescéine contre le blanchiment induit par un oxydant a été évaluée. Résultats et discussion. L'échantillon étudié a montré de bonnes activités antioxydante et antihémolytique. Il n'y a pas eu de différences significatives entre le pouvoir réducteur des substances bioactives liposolubles des fruits et celui de l'acide ascorbique (p < 0,05). L'échantillon testé a montré une faible activité de chélation des ions ferreux et une activité modérée de piégeage du péroxyde d'hydrogène, mais il a présenté une bonne activité antioxydante. Il a révélé une très bonne activité co...

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