Antioxidant and Anti-Sickling Activity of Extracts From the Stem and Roots Barks of Strychnos Innocua (Del.)

BRUKUM, MAWATE FLORANCE; KPEGBA, KAFUI; EVENAMEDE, KODJO SELOM; AGBONON, AMEGNONA; SIMALOU, OUDJANIYOBI

doi:10.22159/ijpps.2023v15i9.48625

Cited by 2 publications

(2 citation statements)

References 20 publications

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“…The quantitative GC-FID determination of the phytochemicals of Gnetum africanum aqueous root extract presented common phytochemicals such as, alkaloids, flavonoids, steroids, phenols and glycosides. These compounds are all known to be the main constituents responsible for the antioxidant activity of plants [9]. Phytochemicals in higher proportions include; sapogenin (26.2645 µg/ml), anthocyanins (17.4986 µg/ml), cyanogenic glycosides (15.3616 µg/ml), kaempferol (13.7621 µg/ml) and flavan-3-ol (13.0446 µg/ml).…”

Section: Discussionmentioning

confidence: 99%

Chemical Analysis of Gnetum africanum roots

Precious Uchenna Asonye,

Chiedozie Onyejiaka Ibegbulem,

Callistus Izunna Iheme

et al. 2024

GSC Biol. Pharm. Sci.

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The use of medicinal plants as complementary therapies has lately grown in popularity. The aim of this study was to determine the chemical composition of the aqueous root extract of Gnetum africanum using GC-MS and GC-FID analysis. Fresh roots of G. africanum Welw used in this study were collected, cut into pieces, washed and air-dried. The dried plant materials were ground into powder and kept in an airtight container. GC-MS analysis of the aqueous root extract revealed 20 bioactive compounds with the following being most abundant 2,3-Butanediol as the predominant phytochemical at 46.02%, followed by Benzene, 1,4-dichloro (3.57%) and Oxalic acid, allyl octadecyl ester (3.45%). The quantitative GC-FID determination of the phytochemicals of Gnetum africanum aqueous root extract presented common phytochemicals such as, alkaloids, flavonoids, steroids, phenols and glycosides. Phytochemicals in higher proportions include; sapogenin (26.2645 µg/ml), anthocyanins (17.4986 µg/ml), cyanogenic glycosides (15.3616 µg/ml), kaempferol (13.7621 µg/ml) and flavan-3-ol (13.0446 µg/ml). It has been discovered that the root of Gnetum africanum contains an array of phytocompounds with a variety of therapeutic properties.

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Section: Discussionmentioning

confidence: 99%

Chemical Analysis of Gnetum africanum roots

Precious Uchenna Asonye,

Chiedozie Onyejiaka Ibegbulem,

Callistus Izunna Iheme

et al. 2024

GSC Biol. Pharm. Sci.

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“…The total flavonoid content was calculated using a quercetin calibration curve and expressed in mg QE/g. [18,19,15].…”

Section: Calculating the Amounts Of All Flavonoidsmentioning

confidence: 99%

Analysis of Flavonoid Content and Antioxidant Activity of Solanum ertianthum Extract

Zebua,

Fujiko,

Dachi

et al. 2024

IOP Conf. Ser.: Earth Environ. Sci.

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Solanum erianthum is one of the herbal plants that is believed by the Indonesian people to be a medicinal plant. The flavonoid and polyphenol compounds contained therein have antioxidant activity, but this has not been proven empirically. Solanum erianthum extract is produced using the maceration method. The determination of total flavonoid levels in Solanum erianthum was measured using a method based on complex formation, namely the aluminum trichloride (AlCl3) method. The antioxidant activity of Solanum erianthum was measured using the DPPH (1,1-diphenyl-2-2picrihydrazyl) method because of its stability in the form of free radicals and because it is simple to carry out. The results obtained after determining the total flavonoid content in Solanum erianthum extract with various concentrations using the aluminum trioxide method were 1,430 mg QE/g, 2,282 mg QE/g, 3,180 mg QE/g, 3,567 mg QE/g, 4,291 mg QE/g. Solanum erianthum extract demonstrated antioxidant activity in the DPPH test, with an IC50 value of 66.493 g/ml. This falls into the “strong” category. This research shows that the phytochemical screening content of Solanum erianthum extract contains alkaloids, flavonoids, tannins, saponins, and tritepenoids. The total flavonoid content in Solanum erianthum extract at concentrations of 6 µg/ml, 8 µg/ml, 10 µg/ml, 12 µg/ml, and 14 µg/ml is as follows: 1,430mg QE/g, 2,282mg QE/g, 3,180mg QE/g, 3,567mg QE/g, and 4,291mg QE/g, as well as the antioxidant activity of Solanum erianthum extract with an average yield of 69,493 ppm.

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Antioxidant and Anti-Sickling Activity of Extracts From the Stem and Roots Barks of Strychnos Innocua (Del.)

Cited by 2 publications

References 20 publications

Chemical Analysis of Gnetum africanum roots

Chemical Analysis of Gnetum africanum roots

Analysis of Flavonoid Content and Antioxidant Activity of Solanum ertianthum Extract

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