Antioxidant and anti-inflammatory properties of novel peptides from Moringa oleifera Lam. leaves

Avilés‐Gaxiola, Sara; León‐Félix, Josefina; Jiménez-Nevárez, Yazmín B.; Angulo-Escalante, Miguel A.; Ramos‐Payán, Rosalío; Colado-Velázquez, Juventino Iii; Heredia, J. Basilio

doi:10.1016/j.sajb.2021.05.033

Cited by 25 publications

(9 citation statements)

References 44 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Complaints about headaches may be linked to the high number and variety of bioactive compounds present in moringa seeds, although there is no evidence in the literature to support this side effect. Few studies on humans have analyzed the health benefits of moringa, but it seems to be well tolerated and to produce no side effects [ 50 , 51 ].…”

Section: Discussionmentioning

confidence: 99%

Moringa as a household water purification method – community perception and pilot study in Guinea-Bissau

et al. 2022

View full text Add to dashboard Cite

Background Public perceptions of water-related issues are still under-researched topics. The current paper intends to explore a local community’s perceptions regarding household water purification (HWP) strategies, namely before and after trying a new method: moringa seeds powder (moringa-teabag). Methods In September 2020, six focus group discussions (N = 65) assessing perceptions about the usefulness of Moringa oleifera Lam (Moringaceae) as a HWP method (before moringa-based HWP trials), and questionnaires (N = 104) evaluating successes and identifying difficulties (after one week of moringa-based HWP trials). Participants were all women aged over 18 years, living in Ondame, Biombo region, Guinea-Bissau. Data were analyzed using qualitative and quantitative approaches. Results The focus group discussions revealed that people are aware of the fact that water can transmit diseases. Although certain persons showed concern about shallow well water safety, people generally underestimate the risk, as they trust tubewell water. Not everyone had an understanding of what water contamination is, or the concept of medical importance. Some respondents declared they use traditional methods such as boiling and bleach to treat water before drinking. However, those who reported no kind of treatment indicated reasons such as lack of time, cost, and bleach’s taste and smell. In the questionnaire, more than half of the participants (68%) reported treating water before consumption. Nevertheless, these results are not consistent with our field notes. Participants demonstrated a strong belief in the capacity of moringa-teabags to purify water and even consider them better or much better (81%) than other methods. Participants asked for more information on moringa-teabag for household water purification. Conclusion More information on water treatment and water safety would help to raise public awareness about waterborne diseases. These findings could be used to promote greater adherence to moringa-based HWP as an alternative to household water treatment.

show abstract

Section: Discussionmentioning

confidence: 99%

Moringa as a household water purification method – community perception and pilot study in Guinea-Bissau

et al. 2022

View full text Add to dashboard Cite

show abstract

“…The optical density was measured to detect nitrite (NO 2 − ) at 570 nm wavelength by Griess method. To remove the effect of the sample on the cell toxicity, MTS was added to the remaining medium to detect the cell viability [ 43 ]. Anti-inflammatory activity was calculated according to the following Equation (5).…”

Section: Methodsmentioning

confidence: 99%

Evaluation of the Biological Activity of Glucosinolates and Their Enzymolysis Products Obtained from Lepidium meyenii Walp. (Maca)

Yan

Wei

Chen

2022

IJMS

View full text Add to dashboard Cite

Glucosinolates (GLS) were extracted and purified from Lepidium meyenii (Maca) root. Purified GLS were analyzed without desulfation by UPLC–ESI–MS. Glucosinolates were decomposed into benzyl isothiocyanate (BITC) by thioglucosidase. DPPH radical scavenging activity, ABTS radical scavenging activity, and reducing power were used to evaluate antioxidant activity of Maca crude extract (MCE), total GLS, and BITC. Maca crude extract showed the highest antioxidant activity among them, and BITC showed no antioxidant activity at concentrations less than 10 mg/mL. Cytotoxicity on five human cancer cell lines and the inhibition rate of NO production were used to evaluate the activity of anti-cancer and anti-inflammatory of total GLS and BITC. The inhibition rate of NO production of 50 μg/mL BITC can reach 99.26% and the cell viability of 100 μg/mL BITC on five tumor cell lines is less than 3%. The results show that BITC may be used as a promising anti-cancer and anti-inflammatory drug.

show abstract

“…To date, fungal cell factories for efficient and sustainable production of proteins and peptides endowed with technological and healthy properties represent a current challenge [ 86 ]. Likewise, edible fungi, M. oleifera seed or leaves protein hydrolysates and related purified peptides showed several beneficial effects, including antioxidant and anti-inflammatory [ 255 ], hypoglycemic [ 231 ], antimicrobial [ 232 ], antihypertensive [ 229 ] properties (see Table 3 ). Partially purified peptides fractions suitable for the regulation of hyperuricemia were also obtained from tryptic hydrolysate of M. oleifera leaves.…”

Section: Bioactive Properties Of Non-meat Proteinsmentioning

confidence: 99%

Alternative Protein Sources and Novel Foods: Benefits, Food Applications and Safety Issues

et al. 2023

View full text Add to dashboard Cite

The increasing size of the human population and the shortage of highly valuable proteinaceous ingredients has prompted the international community to scout for new, sustainable, and natural protein resources from invertebrates (e.g., insects) and underutilized legume crops, unexploited terrestrial and aquatic weeds, and fungi. Insect proteins are known for their nutritional value, being rich in proteins with a good balance of essential amino acids and being a valuable source of essential fatty acids and trace elements. Unconventional legume crops were found rich in nutritional, phytochemical, and therapeutic properties, showing excellent abilities to survive extreme environmental conditions. This review evaluates the recent state of underutilized legume crops, aquatic weeds, fungi, and insects intended as alternative protein sources, from ingredient production to their incorporation in food products, including their food formulations and the functional characteristics of alternative plant-based proteins and edible insect proteins as novel foods. Emphasis is also placed on safety issues due to the presence of anti-nutritional factors and allergenic proteins in insects and/or underutilized legumes. The functional and biological activities of protein hydrolysates from different protein sources are reviewed, along with bioactive peptides displaying antihypertensive, antioxidant, antidiabetic, and/or antimicrobial activity. Due to the healthy properties of these foods for the high abundance of bioactive peptides and phytochemicals, more consumers are expected to turn to vegetarianism or veganism in the future, and the increasing demand for such products will be a challenge for the future.

show abstract

Antioxidant and anti-inflammatory properties of novel peptides from Moringa oleifera Lam. leaves

Cited by 25 publications

References 44 publications

Moringa as a household water purification method – community perception and pilot study in Guinea-Bissau

Moringa as a household water purification method – community perception and pilot study in Guinea-Bissau

Evaluation of the Biological Activity of Glucosinolates and Their Enzymolysis Products Obtained from Lepidium meyenii Walp. (Maca)

Alternative Protein Sources and Novel Foods: Benefits, Food Applications and Safety Issues

Contact Info

Product

Resources

About