Antioxidant and Anti-inflammatory Effects of Bletilla striata Reichenbach fil. Fractions as Cosmetic

Abstract

The antioxidant and anti-inflammatory effects of active ingredients in cosmetics are very important.The effects are closely related to the prevention of skin aging. Among medicinal plants, Bletilla striata Reichenbach fil. has well-known pharmacological activity. Extracted samples were prepared using sequential fractionation of ethyl acetate, butanol, and water. The antioxidant effect of the fractions was confirmed by DPPH and ABTS+ radical scavenging. Among the various fractions of B. striata Reichenbach fil., ethyl acetate was associated with a reduction in nitric oxide production, which was induced by LPS (lipopolysaccharide) treatment in a dose-dependent manner. In addition, the production of iNOS (inducible nitric oxide synthase) and COX-2 (cyclooxygenase-2), which are upstream regulators of nitric oxide production, was also inhibited. Thus, the ethyl acetate fraction of B. striata Reichenbach fil. appears to be a potential active ingredient for use in cosmetics.

Effect of Various Temperatures on Bletillae Rhizoma Polysaccharide Extraction and Physicochemical Properties

“…The backbone of polysaccharides from bletillae rhizome (RBP) is mainly composed of (1→2)-linked α-D-mannopyranose and (1→4)-linked β-D-glucopyranose residues [8]. RBPs have attracted attention due to their biological activity, such as antioxidant properties [9,10], wound healing [11], and promotion of endothelial cell proliferation and vascular endothelial growth factor expression in vitro [12].…”