Antioxidant and anti-inflammatory activities of methanol extract and its fractions from the brown seaweed Spatoglossum schroederi

Júnior, Sérvio Quesado; Carneiro, Victor Hugo Azevedo; Fontenelle, Thais Pontes Carvalho; Chaves, Luciano de Sousa; Mesquita, Jacilane Ximenes; Brito, Tarcísio Vieira de; Prudêncio, Rafael S; Oliveira, Jefferson Soares de; Medeiros, Jand Venes R.; Aragão, Karoline S.; Ribeiro, Ronaldo de Albuquerque; Barbosa, André Luiz dos Reis; Freitas, Ana Lúcia Ponte

doi:10.1007/s10811-014-0497-x

Cited by 11 publications

(8 citation statements)

References 46 publications

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“…The methanolic extract of the brown seaweed Spatoglossum schroederi rich in flavonoids significantly inhibited the paw edema induced by carrageenan or dextran in mice. Results indicated that the anti-inflammatory properties were related to the inhibition of the release of inflammatory mediators and neutrophil infiltration; increasing the release of IL-10 [272]. Similar results were reported for the methanolic extracts of the brown seaweeds Padina tetrastomatica, Dictyota menstrualis, and Sargassum wightii ; the red seaweed Gracilaria edulis ; and the green seaweed Caulerpa racemosa [273,274].…”

Section: Seaweeds Bioactive Effects: From Pre-clinical To Clinicalmentioning

confidence: 64%

Current Trends on Seaweeds: Looking at Chemical Composition, Phytopharmacology, and Cosmetic Applications

et al. 2019

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Seaweeds have received huge interest in recent years given their promising potentialities. Their antioxidant, anti-inflammatory, antitumor, hypolipemic, and anticoagulant effects are among the most renowned and studied bioactivities so far, and these effects have been increasingly associated with their content and richness in both primary and secondary metabolites. Although primary metabolites have a pivotal importance such as their content in polysaccharides (fucoidans, agars, carragenans, ulvans, alginates, and laminarin), recent data have shown that the content in some secondary metabolites largely determines the effective bioactive potential of seaweeds. Among these secondary metabolites, phenolic compounds feature prominently. The present review provides the most remarkable insights into seaweed research, specifically addressing its chemical composition, phytopharmacology, and cosmetic applications.

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Section: Seaweeds Bioactive Effects: From Pre-clinical To Clinicalmentioning

confidence: 64%

Current Trends on Seaweeds: Looking at Chemical Composition, Phytopharmacology, and Cosmetic Applications

et al. 2019

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“…Table 1, Table 2, Table 3 and Table 4 summarize the results of studies on phenolic potential of different brown algae species of different geographical origin: Algeria [39], Australia [28,40,41,42], Brazil [43], China [44,45], Denmark [46], France [47,48,49,50], Iceland [51], India [12,37], Iran [52], Ireland [53,54,55,56,57,58], Japan [59,60,61,62], Korea [63], Lebanon [64], Malaysia [65,66,67], New Zealand [42], Portugal [50], South Korea [68], Spain [69,70,71,72,73], Thailand [74,75], and Tunisia [4,76,77]. The investigated species belong to different orders: Desmarestiales (1 species), Dictyotales (12 species), Ectocarpales (1 species), Fucales (42 species), Laminariales (14 species), Sphacelariales (3 species), and Tilopteridales (1 species).…”

Section: Brown Algae Phenolicsmentioning

confidence: 99%

“…The use of acidified solvents in the study of Kadam et al [58] resulted in lower content of phenolics in comparison to the pure water that can be attributed to the fact that acidic solvents at high temperatures (70 °C) may be detrimental to phenolic compounds althought it could be expected that low pH medium in combination with high temperature could result in hydrolysis of the complex phenolic structures into more simple ones. Júnior et al [43], Wang et al [51] and Tierney et al [56] reported that the use of ACE as extraction solvent gave the highest total yield of extracted phenolics probably due to inhibiting interactions between tannins and proteins during extraction or even by breaking hydrogen bonds between tannin-protein complexes [27]. In the study conducted by Airanthi et al [61], the phenolic contents of Eisenia bicyclis , Kjellmaniella crassifolia, and Alaria crassifolia extracts obtained using different solvents have been reported and the obtained result on the basis of dry seaweed matter as well as per gram of extract.…”

Section: Brown Algae Phenolicsmentioning

confidence: 99%

“…The extraction temperature also varies; from room temperature (RT) usually applied in conventional extractions [39,42,43,61] to significantly high temperatures applied in novel extraction techniques [47,53,62]. The application of high temperatures (above 60 °C) in the extraction procedure mays be questionable for two reasons: i) the susceptibility of phenolic compounds to thermal degradation [24,45], ii) causing hydrolysis of complex phlorotannin compounds into simplex compounds that can generally increase the total phenolic content.…”

Section: Brown Algae Phenolicsmentioning

confidence: 99%

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Phenolic Content of Brown Algae (Pheophyceae) Species: Extraction, Identification, and Quantification

et al. 2019

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Over the last few decades, isolations and chemical characterizations of secondary metabolites with proved biological activities have been of interest for numerous research groups across the world. Phenolics, as one of the largest and most widely distributed group of phytochemicals, have gained special attention due to their pharmacological activity and array of health-promoting benefits. Reports on phenolic potentials of marine algae, especially brown algae (Pheophyceae) that are characterized by the presence of phlorotannins, are still scarce. The aim of this review paper is to provide an overview of current knowledge about phenolic potential of different brown algae species (74 species from 7 different orders). Studies on brown algae phenolics usually involve few species, thus the focus of this review is to provide information about the phenolic potential of reported algae species and to get an insight into some issues related to the applied extraction procedures and determination/quantification methods to facilitate the comparison of results from different studies. The information provided through this review should be useful for the design and interpretation of studies investigating the brown algae as a source of valuable phytochemicals.

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“…Investigation extracts of four species of brown algae Ecklonia radiata, Hormosira banksii, Phyllospora comosa and Myriogloea sciurus shown that nonpolar lipid-rich dichloromethane extracts of these algae had greatest anti-inflammatory activity (via inhibition of nitric oxide), compared with intermediate polarity ethyl acetate extracts and with the lowest activity observed in the polar butanol extracts [23]. Methanol extract and its hexane and chloroform fractions of brown seaweed Spatoglossum schroederi showed anti-inflammatory effect, which may be related to the presence of flavonoids [24]. Phlorotannins [18] [21] [25]- [27], fucosterol [21], pheophorbide and pheophytin a [22] and carotenoid fucoxanthin [28]- [29] inhibited the production of inflammatory mediators also.…”

Section: Introductionmentioning

confidence: 99%

Application of Glyceroglycolipids, Photosynthetic Pigments and Extracts of Brown Algae for Suppression ROS

Gerasimenko¹,

Menchinskaya²,

Esipov³

et al. 2016

OJMS

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Lipid-rich extracts were obtained from brown algae Saccharina cichorioides, Costaria costata, Chorda filum, Eularia fistulosa, Dictyopteris divaricata, Dictyosiphon chordaria, Silvetia babingtonii, and Fucus evanescens that were collected in Peter the Great Gulf of the Sea of Japan. The ability of algal extracts and glyceroglycolipids (GLs) monogalactosyldiacylglycerols (MGDG), digalactosyldiacylglycerols (DGDG), and sulfoquinovosyldiacylglycerols (SQDG) and carotenoid fucoxanthin to suppression of reactive oxygen species (ROS) in lipopolysaccharide (LPS)-stimulated RAW 264.7 macrophage cells, studied.The results showed that algae extracts could suppress ROS. However, extracts of D. divaricata, D. chordaria, C. filum, S. babingtonii, and F. evanescens had a higher degree of suppression of ROS. Extracts of S. cichorioides and D. divaricata showed the dependence of their activity from the month of collecting these algae. The GLs and fucoxanthin were isolated from extracts of using column chromatography with silica gel and their ROS-inhibitory activity was investigated too. The fatty acids (FAs) composition of lipids was determined by GC and GC/MS. It has been found that MGDG and DGDG stronger than SGDG inhibited the ROS and the degree of their activity depended on the species of algae, the month of collection, the amount of PUFA, the ratio of n − 3 and n − 6 PUFA in GLs. Fucoxanthin has shown a high degree of suppression of ROS. This preliminary study has shown the prospect of a deeper study of the suppression of ROS with the help of lipids from algae the Sea of Japan.

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Antioxidant and anti-inflammatory activities of methanol extract and its fractions from the brown seaweed Spatoglossum schroederi

Cited by 11 publications

References 46 publications

Current Trends on Seaweeds: Looking at Chemical Composition, Phytopharmacology, and Cosmetic Applications

Current Trends on Seaweeds: Looking at Chemical Composition, Phytopharmacology, and Cosmetic Applications

Phenolic Content of Brown Algae (Pheophyceae) Species: Extraction, Identification, and Quantification

Application of Glyceroglycolipids, Photosynthetic Pigments and Extracts of Brown Algae for Suppression ROS

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