Antioxidant Activity, Total Phenolic and Flavonoid Contents of Essential Oils of Three Cyperus Species (Cyperaceae)

Lawal, Oladipupo A.; Ojekale, Anthony B.; Oladimeji, Olugbenga S.; Osinaike, Titilola S.; Sanni, Adetayo A.; Simelane, Mthokozisi B. C.; Mosa, Rebamang A.; Opoku, Rita

doi:10.9734/bjpr/2015/18631

Cited by 8 publications

(7 citation statements)

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“…Compounds with antioxidant potentials are becoming increasingly prominent in the combat of these diseases. DPPH and ABTS are artificial free radicals with a similar mechanism of actions as lipophilic radicals that initiate chain reactions through lipid autoxidation (Lawal et al, 2015). Hence, are used to evaluate the scavenging efficacies of crude extracts (Majzoub & Agarwal, 2017;Ojo et al, 2019).…”

Section: Discussionmentioning

confidence: 99%

“…These nitrogen reactive species enhance lipid peroxidation and nitration that elevate malondialdehyde and hydroperoxide production. These cytotoxic products induce cellular structural changes that eventually lead to oxidative stress and cell deaths (Lawal et al, 2015;Oboh et al, 2015). The observed poor nitric oxide scavenging activities of the plants' extracts (Figure No.…”

Section: Discussionmentioning

confidence: 99%

“…Free radicals also known as reactive species (reactive oxygen species and nitric oxide), are chemically reactive molecules that can be by-products of biological reactions such as activation of neutrophils, mitochondria oxidative phosphorylation and autoxidation of dopamine (Pendyala et al, 2008;Halliwell, 2011;Lawal et al, 2015;Reena et al, 2018). Under physiological conditions, free radicals enhance signaling molecules and destruction of antigens or foreign invaders consequently, boosting immunity and promoting good health (Bhakuni et al, 2005;Halliwell, 2011).…”

Section: Introductionmentioning

confidence: 99%

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In vitro and in vivo antioxidant potentials of the methanolic crude extract from Inula glomerata Oliv. & Hiern (Asteraceae) and Salacia kraussii (Harv.) Harv (Celastraceae)

Ojo¹,

Osunsanmi²,

Cele³

et al. 2021

BLACPMA

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Reactive oxygen species are implicated in multiple pathological conditions including erectile dysfunction. This study evaluated the in vitro and in vivo antioxidant potential of the methanolic extracts of Inula glomerata and Salacia kraussii. The plant materials were pulverized and extracted with methanol. The phytochemical analysis, ability of the crude extracts to scavenge free radicals (ABTS, DPPH, NO.) in vitro as well as the total phenolic and flavonoid contents was investigated. In vivo, antioxidant potentials of the crude extracts (50/250 mg/kg body weight) were determined in an erectile dysfunction rat model. The phytochemical analysis revealed that both plants contain flavonoids, tannins, terpenoids, and alkaloids. The crude extracts at varying degree of efficiency, scavenged ABTS and DPPH radicals. The crude extracts at low concentrations (50 mg/kg b.w) significantly (p<0.05) diminished the level of malondialdehyde, augmented catalase activities and elevated glutathione levels. However, SOD activities were significantly boosted in a dose-dependent manner by the crude extracts. Therefore, I. glomerata and S. kraussii possess antioxidant properties, hence, can serve as a therapeutic modality in the treatment of oxidative stress-induced erectile dysfunction.

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Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

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In vitro and in vivo antioxidant potentials of the methanolic crude extract from Inula glomerata Oliv. & Hiern (Asteraceae) and Salacia kraussii (Harv.) Harv (Celastraceae)

Ojo¹,

Osunsanmi²,

Cele³

et al. 2021

BLACPMA

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“…8 The essential oil from Cyperus rotundus has been extensively studied for its antioxidant, bio-molecular protection, and antimicrobial properties and have practical applications in the pharmaceuticals and cosmetics industries. 9,10 Cyperus species plants possess diverse secondary metabolites belonging to flavonoid, alkaloid and terpenoid categories. Rhizome extracts of some Cyperus plants were previously reported to have many health-beneficial properties.…”

Section: Introductionmentioning

confidence: 99%

“…Rhizome extracts of some Cyperus plants were previously reported to have many health-beneficial properties. [9][10][11] Cyperus articulatus was not studied much for its biological or pharmacological importance as compared to other Cyperus species. Traditionally the use of Cyperus articulatus rhizome to treat malaria, epilepsy and dysentery by inhabitants of different countries was reported.…”

Section: Introductionmentioning

confidence: 99%

Phytochemical and Pharmacological Exploration of Cyperus articulatus as a Potential Source of Nutraceuticals and Drug Ingredients

Swain¹,

Santhoshkannada²,

Prabakaran³

et al. 2021

IJPER

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Introduction: Cyperus articulatus rhizome has been used in folk medicine by different inhabitants belonging to tropical and subtropical regions. But its metabolite profile and potential pharmacological and food applications were hardly explored. Evaluation of biological activities of Cyperus articulatus metabolites was the objective of the present study. Materials and Methods: In vitro biological studies concerning radical scavenging, reducing activity, food (meat and β-carotene) protection, biomolecule (DNA and Protein) protection and Acetylcholinesterase inhibitory activity were carried out for the rhizome extracts. Chemical constituents of the bioactive rhizome extract were analyzed through HRLC-MS/MS. Results: The rhizome acetone extract showed the highest antioxidant activity and protected DNA and protein from degradation at the lowest concentrations compared to all the six different solvent extracts tested. It significantly inhibited β-carotene bleaching, controlled the TBARS values during meat oxidation and significantly inhibited the Acetylcholinesterase enzyme. The major compounds detected in HRLC-MS/MS were dihydroquercetin, mycophenolic acid, embelin, quercetrin, meptazinol, koparin-2-methyl ether, venpocentine along with other phenolics and polyhydroxy compounds. Conclusion:The study explored Cyperus articulatus rhizome as a pharmacologically important source for nutraceuticals and drug ingredients and suggested further safety and efficacy studies of the detected metabolites.

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Bioactive Compounds and Biological Activities of Jointed Flat Sedge (Cyperus articulatus L.)

Swain

2023

Reference Series in Phytochemistry

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Antioxidant Activity, Total Phenolic and Flavonoid Contents of Essential Oils of Three Cyperus Species (Cyperaceae)

Cited by 8 publications

References 0 publications

In vitro and in vivo antioxidant potentials of the methanolic crude extract from Inula glomerata Oliv. & Hiern (Asteraceae) and Salacia kraussii (Harv.) Harv (Celastraceae)

In vitro and in vivo antioxidant potentials of the methanolic crude extract from Inula glomerata Oliv. & Hiern (Asteraceae) and Salacia kraussii (Harv.) Harv (Celastraceae)

Phytochemical and Pharmacological Exploration of Cyperus articulatus as a Potential Source of Nutraceuticals and Drug Ingredients

Bioactive Compounds and Biological Activities of Jointed Flat Sedge (Cyperus articulatus L.)

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