Antioxidant Activity Test Of Methanol Extract Of Gaharu (Aquilaria Malaccensis Lam.) Bark With Dpph (1,1 Diphenyl-2-Picrylhydrazyl) Method

Ridwanto, Ridwanto; Trizaldi, Asep; Rani, Zulmai; Daulay, Anny Sartika; Nasution, Haris Munandar; Miswanda, Dikki

doi:10.51601/ijhp.v3i2.123

Cited by 4 publications

(4 citation statements)

References 2 publications

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“…The tannin test was carried out by adding 1% FeCl3. The formation of a black-green color after the addition of 1% FeCl3 indicates the presence of condensed tannins and forms complex compounds with 1% FeCl3 (Ridwanto et al, 2023). The color change did not occur with the addition of FeCl3 because there were no hydroxyl groups present in the tannin compound.…”

Section: Discussionmentioning

confidence: 99%

Determination Of Total Flavonoid Content Of Yellow Wood (Arcangelisia Flava (L.) Merr) Extract And Antibacterial Activity Against Staphylococcus aureus

Yuza,

Ridwanto,

Rani

2023

AMS

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Yellow wood (Arcangelisia flava) is a medicinal plant that has received little attention. Merr and (L.). Yellow wood has antibacterial, antioxidant, anti-hyperlipidemic, and anti-cancer properties. Furthermore, yellow wood is known to contain a range of flavonoid compounds, such as hydroxylarcangelicin, which has broad antibacterial activity. The purpose of this research is to investigate the total flavonoid content of yellowwood extract as well as its antibacterial activity against Staphylococcus aureus bacteria. The manufacturing of methanol extract, characterization of simplisia, phytochemical screening, and determination of the total flavonoid levels of the yellow wood methanol extract by a visible spectroscopic approach were all part of this stage of research. Next, use chloramphenicol as a positive control and dimethyl sulfoxide (DMSO) as a negative control to test antibacterial activity against Staphylococcus aureus. The results of this study can be concluded to show that the total flavonoid levels in the methanol extract of yellow wood at a metanol concentration of 80% were 228,314 ± 5,4171 mg QE/g. At a 90% concentration of 245.993 ± 6.7626 mg QE/g and a 100% concentration of 265.953 3.0853 mg QE/g. Keywords: Yellow wood; Flavonoids; Spektrofotometri Visible; Stphylococcus aureus;

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Section: Discussionmentioning

confidence: 99%

Determination Of Total Flavonoid Content Of Yellow Wood (Arcangelisia Flava (L.) Merr) Extract And Antibacterial Activity Against Staphylococcus aureus

Yuza,

Ridwanto,

Rani

2023

AMS

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“…Kemudian dikeringan di dalam suhu kamar. Proses pengeringan dilakukan sampai akar bajakah mengering dan simplisia yang sudah dikeringkan selanjutnya diserbukkan dengan menggunakan blender kemudian diayak dengan ayakan no 40 sehingga didapatkan halus yang cocok (Syahputra et al, 2021), Serbuk simplisia dimasukkan kedalam wadah tertutup dan disimpan pada suhu kamar dan terlindung dari cahaya matahari (Ridwanto et al, 2023).…”

Section: Pengolahan Sampelunclassified

Penentuan Kadar Alkaloid Total Ektstrak Akar Bajakah (Spatholobus Littoralis Hassk) dengan Metode Spektofotometri Uv-Vis

Hanifah,

Daulay,

Rahman

et al. 2024

jharma

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The Bajakah tampala tree (Spatholobus littoral hassk) is a native plant from the interior of the forests in Kalimantan, especially Central Kalimantan. This plant is a plant that stretches or grows and grows abundantly in the interior of the forest. The Bajakah plant is known to the people of Kalimantan as a medicinal plant and can cure various diseases, including diarrhea, rheumatism, and cancer. The aim of this research was to determine the alkaloid content of bajakah root extract in various concentrations. The research method was carried out experimentally, with the independent variable being an ethanol extract of bajakah roots with concentrations of 50, 70, and 96%. Meanwhile, the dependent variables are the characteristics of simplicia, the secondary metabolite content of Bajakah root ethanol extract, and the determination of the total alkaloid content of Bajakah root extract. Bajakah root simplicia extract is made with 96, 70, and 50% ethanol solvents. The parameters used in this study include water content, total ash content, acid insoluble ash content, water soluble extract content, ethanol soluble extract content, and secondary metabolite content, including alkaloids, tannins, flavonoids, saponins, steroids, and terpenoids, by conducting phytochemical screening. , making a standard caffeine solution, determining the maximum wavelength of caffeine, measuring the caffeine calibration curve, and determining the total alkaloid content of Bajakah root extract. The results of the phytochemical screening showed that Bajakah root was positive for containing alkaloid compounds, saponins, tannins, flavonoids, steroids, and terpenoids. And the results obtained from Bajakah root plants obtained from Central Kalimantan were a 96% ethanol concentration of 1.66797 ± 0.7088 mg/gram, a 70% ethanol concentration of 1.6679 ± 0.1124 mg/gram, and a 50% ethanol concentration of 0.46981 ± 1.0656 mg/gram

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“…Excessive production of free radicals and a lack of antioxidants have an impact on the pathogenesis of several diseases in humans due to oxidative stress in cells 2 . The most appropriate step to reduce oxidative stress is to reduce exposure to free radicals and optimize the body's defenses by increasing antioxidant intake 1 .…”

Section: Introductionmentioning

confidence: 99%

Antioxidant Activity of Fresh Decinte, Fresh Sari, and Fresh Ethanol Extract of Soursop (Annona muricata L.) Leaves Using DPPH Method

Fransiska

Daulay

Ridwanto

et al. 2023

Pharmaceutical and Clinical Journal of Nusantara

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Antioxidants are compounds that are able to ward off or reduce free radicals in the body so that they can prevent several diseases. Soursop leaves (Annona muricata L.) are used as a traditional herbal medicine to prevent or treat cancer, as well as a natural antioxidant, which is usually used by people by boiling it. The purpose of this study was to look at the phytochemical screening by comparing fresh boiled water, fresh juice, and a fresh extract of soursop leaves, as well as test the antioxidant activity with the addition of DPPH (1,1-diphenyl-2-picrylhydrazyl) and measured using a UV-Vis spectrophotometer at 516 nm. The results of the soursop leaf phytochemical screening showed that there were groups of chemical compounds such as flavonoids, glycosides, tannins, and saponins. The results of testing the antioxidant activity by looking at the maximum wavelength of DPPH, using a UV-Vis spectrophotometer, obtained IC50 values for fresh juice of 770.067 µg/mL, fresh decoction of 1,022.8422 µg/mL, and ethanol extract of 299.733 µg/mL. Based on the results of the study, it was shown that the ethanol extract had stronger antioxidant activity than a fresh decoction and the fresh juice of soursop leaves.

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Antioxidant Activity Test Of Methanol Extract Of Gaharu (Aquilaria Malaccensis Lam.) Bark With Dpph (1,1 Diphenyl-2-Picrylhydrazyl) Method

Cited by 4 publications

References 2 publications

Determination Of Total Flavonoid Content Of Yellow Wood (Arcangelisia Flava (L.) Merr) Extract And Antibacterial Activity Against Staphylococcus aureus

Determination Of Total Flavonoid Content Of Yellow Wood (Arcangelisia Flava (L.) Merr) Extract And Antibacterial Activity Against Staphylococcus aureus

Penentuan Kadar Alkaloid Total Ektstrak Akar Bajakah (Spatholobus Littoralis Hassk) dengan Metode Spektofotometri Uv-Vis

Antioxidant Activity of Fresh Decinte, Fresh Sari, and Fresh Ethanol Extract of Soursop (Annona muricata L.) Leaves Using DPPH Method

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