Antioxidant activity of Ruscus species from Serbia: Potential new sources of natural antioxidants

Jakovljević, Violeta D.; Milićević, Jasmina M.; Đelić, Gorica; Vrvić, Miroslav M.

doi:10.2298/hemind140830013j

Cited by 11 publications

(12 citation statements)

References 25 publications

(22 reference statements)

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“…In another study, ethanol, acetone and ethyl acetate extracts obtained using Soxhlet method from the aerial parts of the plant and antioxidant activities of these extracts were investigated. In this study, acetone and ethyl acetate extracts showed the best total antioxidant capacity (23.329 μg AA g -1 ) and the highest DPPH scavenging activity (IC 50 = 182.54 μg mL -1 ) respectively 16 .…”

Section: Anticholinesterase Activitymentioning

confidence: 54%

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Enzyme inhibitory and antioxidant activities of different extracts from ruscus aculeatus l.

Taşkın¹,

Güler²,

Şahin³

et al. 2020

actapharm

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The goal of this work was to evaluate in vitro antioxidant, anti-urease and anticholinesterase activities of Ruscus aculeatus L. using a variety of extracts. Antioxidant activities of different extracts from plant were evaluated using DPPH, FRAP, ABTS/ TEAC and CUPRAC methods. In addition, the anti-urease and anticholinesterase activities of the different extracts were compared by Indophenol and Ellman tests, respectively. In the present study, Soxhlet chloroform extract showed stronger antioxidant (DPPH, FRAP, CUPRAC) and anticholinesterase activity than other extracts. It was also found that the maceration ethanol extract showed the most potent anti-urease activity. The Soxhlet chloroform and maceration ethanol extracts from this species may be a natural resource candidate for the pharmaceutical and food industry due to the pharmacological effects (antioxidant, anticholinesterase and anti-urease effect).

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Section: Anticholinesterase Activitymentioning

confidence: 54%

“…This plant is used for treatment of venous insufficiency / varicosities edema such as circulatory disorders, edema, thrombophlebits, swelling and also used as diuretic. Also it is used in premenstrual syndrome, hemorrhoids, diabetic retinopathy, skin disease, against inflammation and arthritis [14][15][16] .…”

Section: Introductionmentioning

confidence: 99%

Enzyme inhibitory and antioxidant activities of different extracts from ruscus aculeatus l.

Taşkın¹,

Güler²,

Şahin³

et al. 2020

actapharm

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“…Luís et al [ 16 ] described that the methanolic extract of the aerial part showed little antioxidant activity in the DPPH assay, with an IC 50 value of 171.9 mg/L. Other studies, using also the aerial part, reported that ethyl acetate and butanol extracts were the ones that revealed the best activity for the DPPH assay, and obtained EC 50 values of 158 and 173 μg/mL, respectively [ 20 ] and, Jakovljević et al [ 12 ] obtained EC 50 values of 183 μg/mL of ethyl acetate extracts.…”

Section: Resultsmentioning

confidence: 99%

“…Few research groups have already studied this species [ 11 , 12 , 13 ]; the same authors report that the main active ingredients found in R. aculeatus are steroidal saponins (rucogenin and neoruscogenin), which are responsible for its pharmacological effects; other constituents have been isolated, including sterols, triterpenes, flavonoids, coumarins, sparteine, tyramine, and glycolic acid. Moreover, some of the traditional applications of the species seem related to particular compounds, since the highest concentration of ruscogenins is located in the rhizome [ 11 ].…”

Section: Introductionmentioning

confidence: 99%

Phenolic Compounds and Bioactive Properties of Ruscus aculeatus L. (Asparagaceae): The Pharmacological Potential of an Underexploited Subshrub

et al. 2021

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Ruscus aculeatus L. is a subshrub used in traditional medicine in different parts of the world, namely in Europe and the Iberian Peninsula. According to reported folk knowledge, the aerial parts are mainly used as diuretics and the underground organs are used for the treatment of disorders of the urinary system and as a laxative. In this work, the aerial part and the roots and rhizomes of R. aculeatus were chemically characterized with regard to the content of phenolic compounds and bioactive properties. Aqueous (infusions and decoctions) preparations and hydroethanolic extracts from the two mentioned parts of the plant were prepared. Nine phenolic compounds were detected in all the extracts. Apigenin-C-hexoside-C-pentoside isomer II was the major compound in aqueous extracts and, in the hydroethanolic extract was quercetin-O-deoxyhexoside-hexoside followed by apigenin-C-hexoside-C-pentoside isomer II. All extracts revealed antioxidant activity and potential to inhibit some of the assayed bacteria; aqueous extracts of the aerial part and infusions of roots and rhizomes did not show cytotoxic effects on a non-tumor primary cell culture. This preliminary study provides suggestions of the biological potential associated with the empirical uses and knowledge of this species, in particular its bioactivities.

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“…The ABTS•+ radical cation decolorization assay was performed spectrophotometric method. The ABTS+ scavenging activity was calculated previously described by Jakovljević (Jakovljević VD et al, 2016). Briefly, ABTS stock solution (7 mM) with 2.45 mM potassium persulfate.…”

Section: Abts Decolorization Assaymentioning

confidence: 99%

Antioxidant Activity and Total Phenol Anthocyanin and Flavonoid Content Analysis of Rasberry

Goud¹,

Sinha²

2020

International Journal of Advanced Scientific Research and Management

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This study aim to investigate phytochemical and antioxidant activity of Rubus idaeus L fruit. The total phenolics, flavonoids and anthocyanins were evaluated. The antioxidant activities were investigated using three antioxidant assays 2,2diphenyl-1-picrylhydrazyl (DPPH), Ferric Reducing (FRAP) and 2,2′-azinobis(3-ethylbenzothiazoline-6sulfonic acid) (ABTS). The rasberry fruit contain of total phenolics (37.19±0.39 mg GAE/g), flavonoids (5.32±0.13 mg RU/ g) and total anthocyanin content (32.21±0.35 mg c-3-gE/g) were recorded. The antioxidant activity in DPPH assay IC 50 value 39.00±1.32 µg/ml, ABTS assay (0.85±0.02 mg AEAC/g) and FRAP assay 52.03±4.65 mM Fe2+/g were evaluated. These results presenting perspectives usage of R.idaeus fresh fruits was considerable levels of phytochemicals and antioxidant activity.

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Antioxidant activity of Ruscus species from Serbia: Potential new sources of natural antioxidants

Cited by 11 publications

References 25 publications

Enzyme inhibitory and antioxidant activities of different extracts from ruscus aculeatus l.

Enzyme inhibitory and antioxidant activities of different extracts from ruscus aculeatus l.

Phenolic Compounds and Bioactive Properties of Ruscus aculeatus L. (Asparagaceae): The Pharmacological Potential of an Underexploited Subshrub

Antioxidant Activity and Total Phenol Anthocyanin and Flavonoid Content Analysis of Rasberry

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