“…Although most research on the rosemary herb has contemplated its biologically active essential oil, in the past decade R. officinalis aqueous extracts as well as their corresponding water-soluble isolated compounds have been extensively investigated. In addition to expanding knowledge about known medicinal properties of rosemary extracts, which includes antiproliferative and anti-cancer (Petiwala & Johnson, 2015;Shrestha, Song, Kim, Lee, & Cho, 2016;Tai, Cheung, Wu, & Hasman, 2012), anti-inflammatory (Gonçalves et al, 2018;Lucarini et al, 2013), analgesic (Lucarini et al, 2013), neurodegenerative (Rasoul, Maryam, Taghi, & Taghi, 2016), anti-infective (Andrade et al, 2018) and antioxidant (Wollinger et al, 2016;Gonçalves et al, 2018) effects, other biological activities have been reported. A rosemary water-soluble extract, for instance, showed a great potential as antimatrix metalloproteinase-1 agent in human dermal fibroblasts and reconstructed skin, thus figuring a promising ingredient for the prevention of skin photo damage (Martin et al, 2008).…”