Antioxidant Activity of Nocardiopsis sp., a Marine Actinobacterium, Isolated from the Gulf of Mannar Biosphere Reserve, India

Poongodi, Subramaniam; Karuppiah, Valliappan; Sivakumar, K.; Kannan, L.

doi:10.1007/s40009-013-0193-4

Cited by 11 publications

(4 citation statements)

References 16 publications

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“…The IC 50 for DPPH radical scavenging activity of a paper mulberry compound was previously determined to be 6.7 μg mL −1 and that of branch extractions of Distylium racemosum Sieb. et Zucc was determined to be 5.6 μg mL −1 , whereas leaf extracts from different Hibiscus sabdariffa plants were determined to have IC 50 values in the range of 37.33‐320 μg mL −1 (based on leaf dry weight) . The IC 50 value of Nocardiopsis sp.…”

Section: Resultsmentioning

confidence: 99%

Development of actinobacterial resources for functional cosmetics

Dahal

Shim

Kim

2017

J of Cosmetic Dermatology

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Section: Resultsmentioning

confidence: 99%

Development of actinobacterial resources for functional cosmetics

Dahal

Shim

Kim

2017

J of Cosmetic Dermatology

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“…ROS are a group of secondary products that comprise extremely oxidative stress-inducing molecules and the stable “diffusible” non-radical oxidants including H 2 O 2 ( Hayyan et al., 2016 ). Previously, it was reported that the marine actinomycetes derived from corals showed excellent antioxidant activity by scavenging the oxygen radical molecules and was used for the treatment of metabolic disorders ( Poongodi et al., 2014 ; Sugiyama and Hirota, 2014 ). In this present study, the in vitro antioxidant studies confirmed that NHP could scavenge the cancer-causing molecules and act as a potential anticancer drug.…”

Section: Discussionmentioning

confidence: 99%

Structural Characterization, Antimicrobial, Antibiofilm, Antioxidant, Anticancer and Acute Toxicity Properties of N-(2-hydroxyphenyl)-2-phenazinamine From Nocardiopsis exhalans (KP149558)

Ramalingam

Rajendran

Archunan

et al. 2022

Front. Cell. Infect. Microbiol.

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The present study aimed to isolate and identify potential drugs from marine actinomycete Nocardiopsis exhalans and screen them for biomedical applications. The cell-free culture of N. exhalans was extracted with ethyl acetate and the solvent extract showed six fractions in thin-layer chromatography. The fractions were subjected to column chromatography for purification and evaluated for activity against human clinical pathogens. Fraction 4 showed significant activity and was identified as N-(2-hydroxyphenyl)-2-phenazinamine (NHP) using spectral analyses. Further, NHP showed excellent biofilm inhibitory activity against human clinical pathogens Escherichia coli, Pseudomonas aeruginosa, and Staphylococcus aureus. The in vitro antioxidant activity confirmed that NHP is scavenging the oxidative stress-enhancing molecules. The anti-proliferative activity of NHP against human breast cancer cells showed significant activity at 300 µg/ml and less cytotoxic activity against normal cells. Additionally, the toxicity assessment against zebrafish revealed that NHP does not cause any toxicity in the important organs. The results highlight N. exhalans as a promising candidate for the development of antibiotics with potential therapeutic applications.

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“…Following the suggested protocols, an avocado juice methanolic extract was evaluated for in-vitro antioxidant activity [21,28,29]. In brief, 10 mL of methanol (80%) was added to 15 g of the avocado fruit formulation and homogenized.…”

Section: Antioxidant Activitymentioning

confidence: 99%

Scientifically Formulated Avocado Fruit Juice: Phytochemical Analysis, Assessment of Its Antioxidant Potential and Consumer Perception

et al. 2021

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The study’s purpose was to find and create a nourishing fruit juice made from avocado to suit nutritional and health demands. In this regard, the avocado juice was formulated using a statistical technique, and its biochemical and phytochemical characteristics were evaluated. Statistically formulated fruit juice was evaluated for its sensory characteristics, proximate composition, nutrients and vitamins, total phenols and flavonoids, and for its antioxidant ability, in addition to a shelf-life test. The optimal amount of all ingredients included in the mathematical model for the preparation of the juice was 150 g of Persea americana (Avocado) fruit pulp, 12.5 g of honey and 100 mL of water. In fact, the composition of avocado juice was found to have higher phenolic (910.36 ± 0.215 mg EAG g−1/mL) and flavonoid (56.32 ± 1.26 mg QE g−1/ mL) amounts. DPPH, ABTS and FRAP antioxidant assays tended to be high compared with a standard. The shelf-life analysis indicated that the processed avocado juice (V7) had a long shelf life. In view of all these merits, a statistically formulated recipe for avocado fruit juice was recommended for the formulation of the most preferred health drink.

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Antioxidant Activity of Nocardiopsis sp., a Marine Actinobacterium, Isolated from the Gulf of Mannar Biosphere Reserve, India

Cited by 11 publications

References 16 publications

Development of actinobacterial resources for functional cosmetics

Development of actinobacterial resources for functional cosmetics

Structural Characterization, Antimicrobial, Antibiofilm, Antioxidant, Anticancer and Acute Toxicity Properties of N-(2-hydroxyphenyl)-2-phenazinamine From Nocardiopsis exhalans (KP149558)

Scientifically Formulated Avocado Fruit Juice: Phytochemical Analysis, Assessment of Its Antioxidant Potential and Consumer Perception

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