Antioxidant activity of grape products and characterization of components by electrospray ionization mass spectrometry

Oliveira, Diogo Noin de; Sartor, Sabrina de Bona; Damário, Natália; Gollucke, Andréa Pitelli Boiago; Catharino, Rodrigo Ramos

doi:10.1007/s11694-013-9160-5

Cited by 2 publications

(3 citation statements)

References 40 publications

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“…Compound 7 [38]. To the best of our knowledge, caffeoyl tartaric acid and caffeoyl glucose were previously reported primarily in fruit samples such as grape, however, it was the first time that they were reported in seaweeds [39]. [40].…”

Section: Hydroxycinnamic Acids and Other Phenolic Acid Derivativesmentioning

confidence: 99%

LC-ESI-QTOF-MS/MS Characterization of Seaweed Phenolics and Their Antioxidant Potential

et al. 2020

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Seaweed is an important food widely consumed in Asian countries. Seaweed has a diverse array of bioactive compounds, including dietary fiber, carbohydrate, protein, fatty acid, minerals and polyphenols, which contribute to the health benefits and commercial value of seaweed. Nevertheless, detailed information on polyphenol content in seaweeds is still limited. Therefore, the present work aimed to investigate the phenolic compounds present in eight seaweeds [Chlorophyta (green), Ulva sp., Caulerpa sp. and Codium sp.; Rhodophyta (red), Dasya sp., Grateloupia sp. and Centroceras sp.; Ochrophyta (brown), Ecklonia sp., Sargassum sp.], using liquid chromatography electrospray ionization quadrupole time-of-flight mass spectrometry (LC-ESI-QTOF-MS/MS). The total phenolic content (TPC), total flavonoid content (TFC) and total tannin content (TTC) were determined. The antioxidant potential of seaweed was assessed using a 2,2-diphenyl-1-picrylhydrazyl (DPPH) free radical scavenging assay, a 2,2′-azino-bis-3-ethylbenzothiazoline-6-sulfonic acid (ABTS) free radical scavenging assay and a ferric reducing antioxidant power (FRAP) assay. Brown seaweed species showed the highest total polyphenol content, which correlated with the highest antioxidant potential. The LC-ESI-QTOF-MS/MS tentatively identified a total of 54 phenolic compounds present in the eight seaweeds. The largest number of phenolic compounds were present in Centroceras sp. followed by Ecklonia sp. and Caulerpa sp. Using high-performance liquid chromatography-photodiode array (HPLC-PDA) quantification, the most abundant phenolic compound was p-hydroxybenzoic acid, present in Ulva sp. at 846.083 ± 0.02 μg/g fresh weight. The results obtained indicate the importance of seaweed as a promising source of polyphenols with antioxidant properties, consistent with the health potential of seaweed in food, pharmaceutical and nutraceutical applications.

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Section: Hydroxycinnamic Acids and Other Phenolic Acid Derivativesmentioning

confidence: 99%

LC-ESI-QTOF-MS/MS Characterization of Seaweed Phenolics and Their Antioxidant Potential

et al. 2020

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“…Some studies have recently employed modern analytical approaches for EVOO analyses, such as chromatography, spectroscopic techniques and mass spectrometry, for quantification of phenolic compounds and EVOO's adulteration monitoring . Among these tools, electrospray ionization mass spectrometry (ESI‐MS) has been greatly utilized for monitoring of food adulteration, classification and quality control …”

Section: Introductionmentioning

confidence: 99%

“…[21][22][23][24] Among these tools, electrospray ionization mass spectrometry (ESI-MS) has been greatly utilized for monitoring of food adulteration, classification and quality control. [25][26][27] Despite great knowledge on the composition and benefits of EVOO, only recently the absorption of its compounds has been further investigated and discussed, especially at intracellular level; [28] the incorporation at mitochondrial level, however, still remains unknown. [29,30] In the present work, we proposed the use of ESI-MS to elucidate chemical markers that are related to NASH, as well as to characterize the compounds of three different diets (standard, high-fat and high-fat supplemented with EVOO) on whole liver extracts and on Percoll-purified mitochondria.…”

Section: Introductionmentioning

confidence: 99%

Identification of compounds from high‐fat and extra virgin olive oil‐supplemented diets in whole mouse liver extracts and isolated mitochondria using mass spectrometry

et al. 2015

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Nonalcoholic steatohepatitis (NASH) is a fatty liver disorder that could be improved with extra virgin olive oil (EVOO) supplementation in diet. We propose the monitoring, in whole mouse liver extracts and in isolated mitochondria, of the absorption of compounds from three different diets: standard (CT), high-fat (HFD) and high-fat supplemented with EVOO (HFSO). Male mice were submitted to one of the following three diets: CT or HFD for 16 weeks or HFD for 8 weeks followed by additional 8 weeks with HFSO. Following this period, liver was extracted for histological evaluation, mitochondria isolation and mass spectrometry analyses. Diets, liver extracts and Percoll-purified mitochondria were analyzed using ESI-MS and the lipidomics approach. Morphological, histological and spectrometric results indicated a decrease in NASH severity with EVOO supplementation in comparison with animals maintained with HFD. Spectrometric data also demonstrated that some compounds presented on the diets are absorbed by the mitochondria. EVOO was shown to be a potential therapeutic alternative in food for NASH. Our results are in accordance with the proposition that the major factor that influences different responses to diets is their composition - and not only calories - especially when it comes to studies on obesity.

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Antioxidant activity of grape products and characterization of components by electrospray ionization mass spectrometry

Cited by 2 publications

References 40 publications

LC-ESI-QTOF-MS/MS Characterization of Seaweed Phenolics and Their Antioxidant Potential

LC-ESI-QTOF-MS/MS Characterization of Seaweed Phenolics and Their Antioxidant Potential

Identification of compounds from high‐fat and extra virgin olive oil‐supplemented diets in whole mouse liver extracts and isolated mitochondria using mass spectrometry

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