Antioxidant activity of ginger extract and identification of its active components

Mošovská, Silvia; Nováková, D.; Kaliňák, Michal

doi:10.1515/acs-2015-0020

Cited by 50 publications

(34 citation statements)

References 27 publications

(27 reference statements)

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“…Hiserodt (1998) mentioned in his research that [10]-gingerol is active inhibitor of Mycobacterium avium and M. tuberculosis. 25 Ethanolic extract of ginger is best effective against S. aureus when compared with E. feacalis.…”

Section: Antibacterialmentioning

confidence: 99%

“…DPPH radical does not react with flavonoids, which contain no OH-groups in Bring as well as with aromatic acids containing only one OH-group. 25 …”

Section: Antioxidant Activitymentioning

confidence: 99%

“…[6]-gingerol inhibits cell adhesion, invasion, motility and activities of human breast cancer cell lines. 25 …”

Section: Cytotoxic Activitymentioning

confidence: 99%

“…8 In Indonesia, Z. officinale is one of the export commodities, with the development area in 2010 reaching 6,053 ha and the requirement of ginger seed is rhizome 12.106 tons/year. In accordance with the requirements of growing ginger, seed production sites |2| can be selected on land with climate type A, B, or C, with altitude of 300-900 dpl, average temperature [25][26][27][28][29][30] o C, wet month number 7-9 months, rainfall 2,500-4,000 mm/year, with light intensity 70-100%. 14 Ginger is herbaceous rhizomatous perennial, reaching up to 90 cm in height under cultivation.…”

Section: Introductionmentioning

confidence: 99%

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A Review: Is Ginger (Zingiber officinale var. Roscoe) Potential for Future Phytomedicine?

Syafitri¹,

Levita

Mutakin

et al. 2018

IJAS

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Zingiber officinale Roscoe (red:ginger), one of the most widely consumed herbs in Asia, has been empirically used to treat various disorders in Indonesia. There are three known types of ginger: giant ginger or white ginger (Zingiber officinale var. Roscoe), small white ginger or ginger emprit (Zingiber officinale var. Amarum), and red ginger (Zingiber officinale var. Rubrum). The main components of ginger rhizome are carbohydrates, lipids, essential oils, terpenes, and phenol compounds such as gingerol (23-25%) and shogaol (18-25%). Many studies had confirmed beneficial effects of ginger against inflammation, free radicals, diabetes mellitus, bacterial infection, cancer, nausea, etc. Z. officinale var. Roscoe is considered a safe herbal with not significant adverse effects. This plant is potential to be developed for future phytomedicine, however further explorations on its clinical studies in humans is expected, especially the efficacy and safety of the risk of side effects.

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Section: Antibacterialmentioning

confidence: 99%

“…DPPH radical does not react with flavonoids, which contain no OH-groups in Bring as well as with aromatic acids containing only one OH-group. 25 …”

Section: Antioxidant Activitymentioning

confidence: 99%

“…[6]-gingerol inhibits cell adhesion, invasion, motility and activities of human breast cancer cell lines. 25 …”

Section: Cytotoxic Activitymentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

See 2 more Smart Citations

A Review: Is Ginger (Zingiber officinale var. Roscoe) Potential for Future Phytomedicine?

Syafitri¹,

Levita

Mutakin

et al. 2018

IJAS

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“…Pada penelitian menurut Wiraharja et al, ibu hamil yang mengonsumsi jahe bubuk sebanyak 1 g per hari dapat menurunkan mual dan muntah [9]. Penelitian lain juga menunjukkan bahwa mengonsumsi jahe parut sebanyak 1 sendok teh atau 250 mg kapsul jahe bubuk juga dapat menurunkan gejala mual muntah pada ibu hamil [10].…”

Section: Pendahuluanunclassified

Aktivitas Antioksidan pada Minuman Fungsional Berbasis Jahe dan Kacang-Kacangan sebagai Antiemetik

Harti

Kurniasari

Dasilva

et al. 2018

IJHN

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AbstrakAntioksidan merupakan salah satu zat gizi yang dapat menurunkan mual dan muntah. Antioksidan ini dapat ditemukan pada bahan makanan seperti jahe, kacang kedelai, dan kacang hijau. Bahan makanan tersebut dapat dikonsumsi dalam bentuk minuman fungsional. Penelitian ini bertujuan untuk mengetahui aktivitas antioksidan pada minuman fungsional berbasis jahe dan kacangkacangan yang dapat membantu mengatasi mual dan muntah. Desain dari penelitian ini adalah eksploratif deskriptif. Sampel pada penelitian ini yaitu 16 formula yang didapatkan dengan metode d-optimal Mixture Design pada software Design Expert 7 ® . Software design expert ini mampu menentukan proporsi sari jahe, sari kacang hijau, dan sari kacang kedelai. Aktivitas antiosidan diukur menggunakan metode DPPH yang disajikan dalam bentuk nilai aktivitas antioksidan IC50. IC50 didefinisikan sebagai konsentrasi antioksidan yang dapat menangkap 50% radikal bebas DPPH. Hasil penelitian ini menunjukkan bahwa nilai aktivitas antioksidan IC50 formula 1 hingga 16 adalah 109,20; 104,08; 102,66; 147,88; 99,42; 129,89; 132,53; 115,87; 136,94; 109,78; 139,78; 99,33; 102,26; 135,46; 116,07; 120,45 mg/ml. Semakin kecil nilai IC50 menunjukkan bahwa aktivitas antioksidannya semakin baik. Terdapat perbedaan aktivititas antioksidan yang signifikan dari 16 formula (p = 0,0048). Kesimpulan dari penelitian ini yaitu terdapat aktivitas antioksdan pada formula minuman fungsional berbahan dasar jahe dan kacang-kacangan sebesar 99,33 mg/ml hingga147,88 mg/ml. 109.20; 104.08; 102.66; 147.88; 99.42; 129.89; 132.53; 115.87; 136.94; 109.78; 139.78; 99.33; 102.26; 135.46; 116.07; 120.45

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Preparation, characterization, and bioactivity of Zingiber officinale Roscoe powder‐based Pickering emulsions

et al. 2022

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BACKGROUND: Biocompatible Pickering emulsions (PE) stabilized by tailor-made antioxidant-loaded particles have been known for some time now, but antioxidant-rich natural plant particle-based emulsions are much less well known. This study aimed to investigate the physico-chemical properties of commercial Zingiber officinale powders obtained from biological and conventional agricultural practice and ginger powder-based PE.RESULTS: The physico-chemical and biological properties of Zingiber officinale powders (GDPs) obtained from conventional (GDPC1 and GDPC2) and biological agricultural (GDPBIO) practices, and the properties of derived PE (PE_GDPs) were examined. All GDPs showed weak aggregation in aqueous media and a sufficiently hydrophobic surface to stabilize oil-in-water (O/W) PE against coalescence for at least 1 month. Zingiber officinale powders (2% w/w) derived from biological agricultural practices (GDPBIO) demonstrated the best emulsifying properties. The Zingiber officinale powders and PE_GDPs were also characterized by their phytochemical profiles. All the investigated samples exhibited ferric reducing ability power greater than the positive control, butylated hydroxytoluene (BHT), with values ranging from 91.21 to 102.63 ∼mol L −1 Fe (II) g −1 for GDPC2 and 05PE_GDPC1 (O/W=1:1), respectively. In ⊎-carotene bleaching test the following trend GDPC1 > GDPBIO > GDPC2 was observed. A 05PE_GDPBIO sample with the oil volume fraction equal to 50% was stable to oxidation and exhibited a promising ⊍-amylase inhibitory activity.CONCLUSION: The results suggest that ginger powder should be used as a starting point to design biocompatible PEs for different applications in the functional food, nutraceutical, and pharmaceutical industries. In fact, powder and based PE are characterized by a promising antioxidant activity, carbohydrate hydrolyzing enzyme and lipase inhibitory properties. Further in vivo studies are necessary to confirm these findings.

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Antioxidant activity of ginger extract and identification of its active components

Cited by 50 publications

References 27 publications

A Review: Is Ginger (Zingiber officinale var. Roscoe) Potential for Future Phytomedicine?

A Review: Is Ginger (Zingiber officinale var. Roscoe) Potential for Future Phytomedicine?

Aktivitas Antioksidan pada Minuman Fungsional Berbasis Jahe dan Kacang-Kacangan sebagai Antiemetik

Preparation, characterization, and bioactivity of Zingiber officinale Roscoe powder‐based Pickering emulsions

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