Antioxidant Activity of European Mistletoe (Viscum album)

Vicaş, Simona Ioana; Rugină, Dumitriţa; Socaciu, Carmen

doi:10.5772/26845

Cited by 5 publications

(1 citation statement)

References 32 publications

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“…Another study utilizing HPLC to analyze the phenolic compounds composition of Viscum album leaf and stem extracts from northwest Romania parasitic on five different host trees, Acer campestre (VAA), Mallus domestica (VAM), Fraxinus excelsior (VAF), Populus nigra (VAP) and Robinia pseudoacacia (VAR) identified 17 compounds and these include a pentacyclic triterpene (betulinic acid), 12 phenolic acids (gallic acid, protocatechuic acid, gentisic acid, chlorogenic acid, p -OH benzoic acid, caffeic acid, syringic acid, salicilyc acid, p -coumaric acid, ferulic acid, sinapic acid, and trans- cinnamic acid) and four polyphenols (naringenin, quercetin, kaempherol and rosmarinic acid) [126]. In addition, quantitative HPLC analysis also showed that the leaves of Viscum album contain higher concentration of bioactive compounds compared to stems [126].…”

Section: Ethnomedicinal Usesmentioning

confidence: 99%

Parasitic Mistletoes of the Genera Scurrula and Viscum: From Bench to Bedside

et al. 2016

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Abstract:The mistletoes, stem hemiparasites of Asia and Europe, have been used as medicinal herbs for many years and possess sophisticated systems to obtain nutrients from their host plants. Although knowledge about ethnomedicinal uses of mistletoes is prevalent in Asia, systematic scientific study of these plants is still lacking, unlike its European counterparts. This review aims to evaluate the literature on Scurrula and Viscum mistletoes. Both mistletoes were found to have anticancer, antimicrobial, antioxidant and antihypertensive properties. Plants from the genus Scurrula were found to inhibit cancer growth due to presence of phytoconstituents such as quercetin and fatty acid chains. Similar to plants from the genus Viscum, Scurrula also possesses TNFα activity to strengthen the immune system to combat cancer. In line with its anticancer activity, both mistletoes are rich in antioxidants that confer protection against cancer as well as neurodegeneration. Extracts from plants of both genera showed evidence of vasodilation and thus, antihypertensive effects. Other therapeutic effects such as weight loss, postpartum and gastrointestinal healing from different plants of the genus Scurrula are documented. As the therapeutic effects of plants from Scurrula are still in exploration stage, there is currently no known clinical trial on these plants. However, there are few on-going clinical trials for Viscum album that demonstrate the functionalities of these mistletoes. Future work required for exploring the benefits of these plants and ways to develop both parasitic plants as a source of pharmacological drug are explained in this article.

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Section: Ethnomedicinal Usesmentioning

confidence: 99%

Parasitic Mistletoes of the Genera Scurrula and Viscum: From Bench to Bedside

et al. 2016

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Flavonoids: isolation, characterization, and health benefits

Ekalu¹,

Habila

2020

Beni-Suef Univ J Basic Appl Sci

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Background The unique and vast pharmacological activities of flavonoids have made them of research interest. This led to the use of various techniques to isolate and characterize them, intending to determine their potential health benefits. Main text The medicinal values of plant-based flavonoids that this literature review tends to summarize the pharmacological activities of these secondary metabolites from 22 selected plant families. The pharmacological shreds of evidence reported in the literature have proven that flavonoids have shown anti-cancer, anti-microbial, anti-oxidant, anti-inflammatory, anti-fungal, anti-ulcer, and anti-edematogenic activities. Out of these, 30% showed to have anti-oxidant activity, key in protecting the body against free radicals. Besides, 18% of the references showed anti-microbial and anti-cancer activities. Further literature reports indicated that flavonoids from these families exhibited anti-inflammatory and anti-edematogenic (9%), anti-viral and anti-ulcer (5%), anti-fungal, anti-nociceptive, and anti-histamine (2%). Conclusion The pharmacological activities of flavonoids from the various sources reviewed in this study show that the secondary metabolites could provide a scaffold for the development of potent anti-cancer drugs in the future.

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Changes in Antioxidant Enzyme Activities of European Mistletoe (Viscum album L. subsp. Album) Leaves as a Response to Environmental Stress Caused by Pollution of the Atmosphere by Nitrogen Dioxide

Patykowski¹,

Kołodziejek²

2016

Pol. J. Environ. Stud.

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In the present study we investigated the seasonal pattern of activity of antioxidant enzymes such as superoxide dismutase (SOD) catalase (CAT) ascorbate peroxidase (APX), guaiacol peroxidase (POD) and syringaldazine peroxidase (SPOD) as well as the total protein concentration in the European mistletoe (Viscum album L. subsp. album). We studied mistletoe leaves that grew on the selected tree species in different parts the city of Lodz, exposed to a greater or lesser extent to the nitrogen dioxide. Sampling campaigns were conducted during the growing season 2013 in early May (at the beginning of the growing season) and in November (at the end of the growing season). We showed considerable seasonal variations of antioxidant enzymatic activity and total protein concentrations for all the samples studied. The test parameters varied depending on the host plants exposition to pollution with nitrogen dioxide. The changes in enzymatic activity did not depend on the host plants. In mistletoe leaves greater changes of SOD activity and total protein concentration were observed in autumn. There is correlation between the level of nitrogen dioxide in atmosphere and activities the enzymes. SOD activity was signifi cantly higher in autumn when the host plants were defoliated. Increased CAT activity was observed in late spring. We demonstrated the positive correlation between changes in enzyme activities and the progress of growing season. Increased activities of POD, CAT and APX to a limited extent depended on the place of growing and exposition to air pollution. In late spring activity of the enzymes did not signifi cant grow because of the protective umbrella from host plant leaves preventing the access of nitrogen dioxide to mistletoe. The higher SOD activity in mistletoe is a consequence of oxidative stress causes by nitrogen dioxides evidently observed in the city center. The test parameters, mainly the activity of SOD, can be used in the future as markers of the

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Antioxidant Activity of European Mistletoe (Viscum album)

Cited by 5 publications

References 32 publications

Parasitic Mistletoes of the Genera Scurrula and Viscum: From Bench to Bedside

Parasitic Mistletoes of the Genera Scurrula and Viscum: From Bench to Bedside

Flavonoids: isolation, characterization, and health benefits

Changes in Antioxidant Enzyme Activities of European Mistletoe (Viscum album L. subsp. Album) Leaves as a Response to Environmental Stress Caused by Pollution of the Atmosphere by Nitrogen Dioxide

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