Antioxidant activity of effluents during the purification of hydroxytyrosol and 3,4-dihydroxyphenyl glycol from olive oil waste

Rodríguez, Guillermo; Rodríguez, Rafael Moreno; Fernández‐Bolaños, Juan; Guillén, Rafael; Jiménez, Ana

doi:10.1007/s00217-006-0366-1

Cited by 59 publications

(42 citation statements)

References 29 publications

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“…A solution containing at least 75% HT present in the olive by-products was obtained. Removal of the solvents afforded a fraction of HT with 95% purity plus significant fractions up to 99.6% purity (previously called Hytolive ® 1 [108]). …”

Section: Purification Of Hydroxytyrosolmentioning

confidence: 99%

“…These compounds also showed equivalent values of ferric reducing power (0.102 quercitin equivalent for 1 mM HT) than that measured for 1 mM of vitamin E (0.107 quercitin equivalent), but higher than 1 mM vitamin C (0.061 quercitin equivalent). In the assays that involve lipid oxidation, inhibition of primary oxidation products, and inhibition of secondary oxidation products (TBARS, thiobarbituric acid-reactive substances) HT showed an intermediate activity between the more active vitamin E and the less active vitamin C [108].…”

Section: Purification Of Hydroxytyrosolmentioning

confidence: 99%

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Hydroxytyrosol and Derivatives: Isolation, Synthesis, and Biological Properties

Fernandez‐Bolanos¹,

López²,

Fernández‐Bolaños³

et al. 2008

COC

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Hydroxytyrosol is a phenol found predominantly in the olive tree (Olea europea). It shows a broad spectrum of beneficial effects such as cancer chemoprevention by inducing apoptosis, cardioprotection and anti-atherogenic activity, skin photoprotection and anti-inflammatory activity. These biological properties are based on scavenging of reactive oxygen species by hydroxytyrosol, being more active than antioxidant vitamins and synthetic antioxidants. Its biological activities and beneficial effects on human health has stimulated the development of new methods of extraction and purification from olive mill wastewater, from table olive processing, or from leaves. Different procedures for the chemical and enzymatic synthesis of hydroxytyrosol have been developed from tyrosol, from 3,4-dihydroxyphenylacetic acid and its methyl ester, and from oleuropein.Some hydroxytyrosol acyl derivatives have been prepared by chemical and chemoenzimatic methods in order to increase both stability and solubility in lipophilic preparations. Mechanistic experiments on hydroxytyrosol oxidation and isolation of species formed by oxidation are also reported.

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Section: Purification Of Hydroxytyrosolmentioning

confidence: 99%

Section: Purification Of Hydroxytyrosolmentioning

confidence: 99%

Hydroxytyrosol and Derivatives: Isolation, Synthesis, and Biological Properties

Fernandez‐Bolanos¹,

López²,

Fernández‐Bolaños³

et al. 2008

COC

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show abstract

“…2 It exerts a broad spectrum of biological activities based on its antioxidant properties such as cancer chemoprevention, cardioprotection, anti-inflammatory properties or skin photoprotection. 1,3,4 Hydroxytyrosol (HT) acts as a more potent radical scavenger than other natural or less popular synthetic antioxidants, probably due to the low value of the OeH bond dissociation enthalpy.…”

Section: Introductionmentioning

confidence: 99%

Complexation of hydroxytyrosol with β-cyclodextrins. An efficient photoprotection

et al. 2010

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“…The inhibition capacity of secondary oxidation was evaluated by a modification of the thiobarbituric acid reactive species method (Rodríguez et al . ) on the extracted muffin fat. Sixty microliter of fat and 5 μL of ABAP were added to an Eppendorf tube (1.5 mL capacity) and made up to 0.1 mL with distilled water (in quadruplicate).…”

Section: Methodsmentioning

confidence: 99%